Page last updated: 2024-08-26

selenazofurin and tiazofurin

selenazofurin has been researched along with tiazofurin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199012 (57.14)18.7374
1990's4 (19.05)18.2507
2000's5 (23.81)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Robins, RK; Srivastava, PC1
Cappellacci, L; De Montis, A; Franchetti, P; Goldstein, BM; Grifantini, M; Gurudutt, VV; Jayaram, HN; Jones, WD; La Colla, P; Loi, AG; Perra, G; Schneider, BP; Sheikha, GA; Sint, T1
Cottam, HB; Fujitaki, JM; Matsumoto, SS; Ojo-Amaize, E; Parandoosh, Z; Revankar, GR; Robins, RK; Rubalcava, B; Smee, DF; Willis, RC1
Belei, M; Parandoosh, Z; Robins, RK; Rubalcava, B1
Ahluwalia, GS; Cooney, DA; Dion, RL; Gebeyehu, G; Jayaram, HN; Johns, DG; Kelley, JA; Marquez, VE; Van Cott, A; Wilson, YA1
Lee, HJ; Nguyen, BT; Pawlak, K; Robins, RK; Sadée, W1
Blair, OC; Sartorelli, AC; Sokoloski, JA1
Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y1
Berger, NA; Berger, SJ; Catino, DM; Petzold, SJ; Robins, RK1
Berry, DA; Besserer, JA; Boritzki, TJ; Cook, PD; Fry, DW; Jackson, RC; Leopold, WR1
Ahluwalia, GS; Cooney, DA; Dion, RL; Gebeyehu, G; Jayaram, HN; Johns, DG; Kelley, JA; Marquez, VE; Robins, RK1
Robins, RK; Streeter, DG1
Canonico, PG; Huggins, JW; Robins, RK1
Cooney, DA; Gharehbaghi, K; Hao, Z; Jayaram, HN; Krohn, K; Paull, KD; Sreenath, A; Szekeres, T1
Cooney, DA; Grusch, M; Jayaram, HN; Krupitza, G1
Franchetti, P; Grifantini, M1
Goldstein, BM; Jayaram, HN; Lesiak-Watanabe, K; Pankiewicz, KW; Watanabe, KA1
Gharehbaghi, K; Grünberger, W; Jayaram, HN1
Hasmann, M; Nuessler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I1
Bray, M; Endy, TP; Paragas, J; Whitehouse, CA1
Arterburn, JB; Bartolucci, A; Chung, DH; Jonsson, CB; Parker, WB; Sun, Y1

Reviews

2 review(s) available for selenazofurin and tiazofurin

ArticleYear
Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.
    Current medicinal chemistry, 1999, Volume: 6, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; cdc25 Phosphatases; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Guanosine Triphosphate; HL-60 Cells; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Neoplasms; Nucleosides; Organoselenium Compounds; Ovarian Neoplasms; Protein Tyrosine Phosphatases; Ribavirin; Ribonucleosides; RNA, Messenger; Time Factors; Tumor Cells, Cultured

1999
Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents.
    Current medicinal chemistry, 1999, Volume: 6, Issue:7

    Topics: Antineoplastic Agents; Antiviral Agents; Humans; IMP Dehydrogenase; Inhibitory Concentration 50; K562 Cells; Mycophenolic Acid; Nucleosides; Organoselenium Compounds; Oxazoles; Ribavirin; Ribonucleosides; Ribose; Tumor Cells, Cultured

1999

Other Studies

19 other study(ies) available for selenazofurin and tiazofurin

ArticleYear
Synthesis and antitumor activity of 2-beta-D-ribofuranosylselenazole-4- carboxamide and related derivatives.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Lung Neoplasms; Mice; Ribonucleosides; Selenium

1983
Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Division; Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Inosine Monophosphate; Leukemia; Lymphoma; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Structure; Neoplasms; Organoselenium Compounds; Ribavirin; Ribonucleosides; Tumor Cells, Cultured

1997
Nucleoside and nucleotide modulation of genetic expression--a new approach to chemotherapy.
    Advances in enzyme regulation, 1989, Volume: 29

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Down-Regulation; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Humans; Nucleosides; Nucleotides; Organoselenium Compounds; Phosphorylation; Ribavirin; Ribonucleosides; Selenium; Signal Transduction; Tumor Cells, Cultured

1989
Tiazofurin and selenazofurin induce depression of cGMP and phosphatidylinositol pathway in L1210 leukemia cells.
    Biochemical and biophysical research communications, 1989, Oct-31, Volume: 164, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Caenorhabditis elegans Proteins; Carrier Proteins; Cyclic GMP; Diglycerides; Guanosine Triphosphate; Inosine Monophosphate; Leukemia L1210; Mice; Organoselenium Compounds; Phorbol 12,13-Dibutyrate; Phosphates; Phosphatidylinositols; Protein Kinase C; Receptors, Drug; Ribavirin; Ribonucleosides; Selenium

1989
Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:1

    Topics: Animals; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia P388; Mice; NAD; Organoselenium Compounds; Ribavirin; Ribonucleosides; Selenium

1985
Biochemical differences among four inosinate dehydrogenase inhibitors, mycophenolic acid, ribavirin, tiazofurin, and selenazofurin, studied in mouse lymphoma cell culture.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 1

    Topics: Adenosine Triphosphate; Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanine; Guanylate Kinases; Hypoxanthine Phosphoribosyltransferase; IMP Dehydrogenase; Ketone Oxidoreductases; Lymphoma; Mice; Mycophenolic Acid; Nucleoside-Diphosphate Kinase; Nucleoside-Phosphate Kinase; Organoselenium Compounds; Ribavirin; Ribonucleosides; RNA, Neoplasm; Selenium; Tritium; Uridine

1985
Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Cell Cycle; Cell Differentiation; Cell Line; Dolichol Monophosphate Mannose; Glycoproteins; Guanosine; Guanosine Triphosphate; Hematopoiesis; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia, Myeloid, Acute; Mycophenolic Acid; Organoselenium Compounds; Phagocytosis; Ribavirin; Ribonucleosides; Selenium

1986
Synergistic cytotoxic effect of tiazofurin and ribavirin in hepatoma cells.
    Biochemical and biophysical research communications, 1988, May-31, Volume: 153, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Drug Synergism; Guanosine Monophosphate; IMP Dehydrogenase; Liver Neoplasms, Experimental; Organoselenium Compounds; Purines; Rats; Ribavirin; Ribonucleosides; Selenium

1988
Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin. A new strategy for cancer chemotherapy.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:2

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Leukemia L1210; Mice; NAD; Nucleoside Diphosphate Sugars; Organoselenium Compounds; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Ribavirin; Ribonucleosides; Selenium

1985
Biochemical and antitumor activity of tiazofurin and its selenium analog (2-beta-D-ribofuranosyl-4-selenazolecarboxamide).
    Biochemical pharmacology, 1985, Apr-01, Volume: 34, Issue:7

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Humans; Mice; Neoplasms; Nucleic Acids; Organoselenium Compounds; Ribavirin; Ribonucleosides; Ribonucleotides; Selenium

1985
Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.
    Biochemical pharmacology, 1983, Sep-01, Volume: 32, Issue:17

    Topics: Animals; Gas Chromatography-Mass Spectrometry; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia P388; Leukemia, Experimental; Mice; NAD; Organoselenium Compounds; Ribavirin; Ribonucleosides; Selenium

1983
Comparative in vitro studies of Tiazofurin and a selenazole analog.
    Biochemical and biophysical research communications, 1983, Sep-15, Volume: 115, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Survival; IMP Dehydrogenase; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Nucleoside-Diphosphate Kinase; Organoselenium Compounds; Ribavirin; Ribonucleosides; Selenium

1983
Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:4

    Topics: Antiviral Agents; Arenaviridae; Bunyaviridae; Drug Combinations; Drug Synergism; IMP Dehydrogenase; Organoselenium Compounds; Ribavirin; Ribonucleosides; Selenium; Togaviridae

1984
Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin.
    Biochemical pharmacology, 1994, Oct-07, Volume: 48, Issue:7

    Topics: Antineoplastic Agents; Cell Survival; Glutamate Dehydrogenase; Humans; IMP Dehydrogenase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Nucleosides; Organoselenium Compounds; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured

1994
The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside.
    Current medicinal chemistry, 2002, Volume: 9, Issue:7

    Topics: Antineoplastic Agents; Cell Survival; Humans; IMP Dehydrogenase; NAD; Niacinamide; Organoselenium Compounds; Pyridinium Compounds; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured

2002
Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase.
    Current medicinal chemistry, 2002, Volume: 9, Issue:7

    Topics: Antineoplastic Agents; Cell Survival; Central Nervous System Neoplasms; Humans; IMP Dehydrogenase; Isoenzymes; Nucleosides; Organoselenium Compounds; Ribavirin; Ribonucleosides; Sarcoma; Tumor Cells, Cultured

2002
Cytoprotective features of selenazofurin in hematopoietic cells.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:8

    Topics: Antineoplastic Agents; Cell Death; Cell Line; Cell Survival; Chlorambucil; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Monocytic, Acute; Methylnitronitrosoguanidine; Organoselenium Compounds; Ribavirin; Ribonucleosides

2002
A simple assay for determining antiviral activity against Crimean-Congo hemorrhagic fever virus.
    Antiviral research, 2004, Volume: 62, Issue:1

    Topics: Animals; Antiviral Agents; Azauridine; Cell Line; Chlorocebus aethiops; Coloring Agents; Cricetinae; Fibroblasts; Hemorrhagic Fever Virus, Crimean-Congo; Humans; Microbial Sensitivity Tests; Neutral Red; Organoselenium Compounds; Ribavirin; Ribonucleosides; Staining and Labeling; Vero Cells; Viral Plaque Assay; Virus Replication

2004
Ribavirin reveals a lethal threshold of allowable mutation frequency for Hantaan virus.
    Journal of virology, 2007, Volume: 81, Issue:21

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Gene Frequency; Genome, Viral; Guanosine Triphosphate; Hantaan virus; Mutation; Mycophenolic Acid; Organoselenium Compounds; Ribavirin; Ribonucleosides; RNA, Viral; Vero Cells

2007