Page last updated: 2024-08-23

selegiline and propargylamine

selegiline has been researched along with propargylamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's8 (72.73)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Barber, QR; Bergh, JJ; Joubert, J; Malan, SF; Petzer, JP; Zindo, FT1
Boulton, AA; Davis, BA; Fang, J; Yu, PH1
Carrillo, MC; Kitani, K; Maruyama, W; Naoi, M; Yamamoto, T; Youdim, M1
Carrillo, MC; Ivy, GO; Kanai, S; Kitani, K; Maruyama, W; Minami, C1
Carrillo, MC; Ivy, GO; Kanai, S; Kitani, K; Minami, C; Yamamoto, T1
Chalmers-Redman, R; Tatton, N; Tatton, W1
Jenner, P1
Olanow, CW1
Kálmán, M; Pálfi, M; Szökó, E1
Akao, Y; Maruyama, W; Naoi, M; Shamoto-Nagai, M; Yamaoka, Y; Yi, H1
Legoabe, LJ; Meiring, L; Petzer, A; Petzer, JP1

Reviews

4 review(s) available for selegiline and propargylamine

ArticleYear
Pharmacological interventions in aging and age-associated disorders: potentials of propargylamines for human use.
    Annals of the New York Academy of Sciences, 2002, Volume: 959

    Topics: Aging; Animals; Catalase; Free Radical Scavengers; Humans; Life Expectancy; Neuroprotective Agents; Pargyline; Propylamines; Selegiline; Superoxide Dismutase

2002
Neuroprotection by deprenyl and other propargylamines: glyceraldehyde-3-phosphate dehydrogenase rather than monoamine oxidase B.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:5

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Glyceraldehyde-3-Phosphate Dehydrogenases; HSP70 Heat-Shock Proteins; Humans; Monoamine Oxidase; Neurons; Neuroprotective Agents; Pargyline; Parkinson Disease; Propylamines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Selegiline; Superoxide Dismutase

2003
Preclinical evidence for neuroprotection with monoamine oxidase-B inhibitors in Parkinson's disease.
    Neurology, 2004, Oct-12, Volume: 63, Issue:7 Suppl 2

    Topics: Amphetamines; Animals; Antiparkinson Agents; Apoptosis; Clinical Trials as Topic; Drug Evaluation, Preclinical; Haplorhini; Humans; Inactivation, Metabolic; Indans; Mice; Mice, Transgenic; Models, Neurological; Monoamine Oxidase Inhibitors; Neurons; Neuroprotective Agents; Oxepins; Oxidative Stress; Pargyline; Parkinson Disease; Propylamines; Selegiline

2004
[Molecular mechanisms of the neuroprotective effect of (-)-deprenyl].
    Orvosi hetilap, 2006, Jul-09, Volume: 147, Issue:27

    Topics: Animals; Antioxidants; Antiparkinson Agents; Apoptosis; Dopamine; Drug Synergism; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Mitochondria; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Pargyline; Phosphotransferases; Poly(ADP-ribose) Polymerases; Propylamines; Selegiline

2006

Other Studies

7 other study(ies) available for selegiline and propargylamine

ArticleYear
Polycyclic propargylamine and acetylene derivatives as multifunctional neuroprotective agents.
    European journal of medicinal chemistry, 2014, Jun-10, Volume: 80

    Topics: Acetylene; Apoptosis; Calcium Channel Blockers; Calcium Channels, L-Type; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Pargyline; Propylamines; Protein Conformation; Receptors, N-Methyl-D-Aspartate

2014
Neuroprotective effects of some monoamine oxidase-B inhibitors against DSP-4-induced noradrenaline depletion in the mouse hippocampus.
    Journal of neurochemistry, 1994, Volume: 63, Issue:5

    Topics: Animals; Benzylamines; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Male; Mice; Monoamine Oxidase Inhibitors; Neurons; Neurotransmitter Uptake Inhibitors; Norepinephrine; Pargyline; Phenelzine; Propylamines; Selegiline; Time Factors

1994
Mechanism underlying anti-apoptotic activity of a (-)deprenyl-related propargylamine, rasagiline.
    Mechanisms of ageing and development, 2000, Jul-31, Volume: 116, Issue:2-3

    Topics: Animals; Apoptosis; Humans; Indans; Molecular Structure; Molsidomine; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Pargyline; Propylamines; Rats; Rats, Inbred F344; Selegiline; Tumor Cells, Cultured

2000
Common properties for propargylamines of enhancing superoxide dismutase and catalase activities in the dopaminergic system in the rat: implications for the life prolonging effect of (-)deprenyl.
    Journal of neural transmission. Supplementum, 2000, Issue:60

    Topics: Age Factors; Animals; Brain; Catalase; Dogs; Dopamine; Dose-Response Relationship, Drug; Longevity; Mice; Mice, Inbred Strains; Pargyline; Propylamines; Rats; Rats, Inbred Strains; Selegiline; Sex Factors; Superoxide Dismutase

2000
Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease.
    Neurology, 2006, May-23, Volume: 66, Issue:10 Suppl 4

    Topics: Clinical Trials as Topic; Evidence-Based Medicine; Humans; Indans; Neuroprotective Agents; Pargyline; Parkinson Disease; Practice Guidelines as Topic; Practice Patterns, Physicians'; Propylamines; Selegiline; Treatment Outcome

2006
Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers.
    Journal of neural transmission. Supplementum, 2007, Issue:72

    Topics: Alkynes; Cell Death; Cell Line, Tumor; Energy Metabolism; Genetic Markers; Glial Cell Line-Derived Neurotrophic Factor; Humans; Indans; Membrane Potentials; Mitochondria; Neuroblastoma; Neuroprotective Agents; NF-kappa B; Oligonucleotide Array Sequence Analysis; Pargyline; Parkinson Disease; Propylamines; Proto-Oncogene Proteins c-bcl-2; Selegiline

2007
The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase.
    Bioorganic & medicinal chemistry letters, 2022, 07-01, Volume: 67

    Topics: Humans; Indans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Parkinson Disease; Propylamines; Selegiline; Tetrahydronaphthalenes; Tyramine

2022