Page last updated: 2024-08-23

selegiline and oxidopamine

selegiline has been researched along with oxidopamine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19907 (26.92)18.7374
1990's10 (38.46)18.2507
2000's6 (23.08)29.6817
2010's3 (11.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, YT; Cipriani, PG; Gunsalus, K; Kang, M; Khersonsky, SM; Kyung Kim, Y; Lee, JY; Min, J; Niessen, S; Piano, F; Walsh, DP; Yates, JR1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Gramsbergen, JB; Korf, J; Sebens, JB1
Greenshaw, AJ; Juorio, AV; Nguyen, TV2
Fozard, JR; Palfreyman, MG; Robin, M; Zreika, M2
Knoll, J1
Cabbat, FS; Duvoisin, RC; Heikkila, RE; Manzino, L1
Bankiewicz, KS; Finberg, JP; Goldstein, DS; Kopin, IJ; Wang, J1
Adams, CE; Boyson, SJ; Hoffer, BJ; Hoffman, AF; Hudson, JL1
Abercrombie, ED; Wachtel, SR1
Ebadi, M; Pfeiffer, RF; Shiraga, H1
Blumgart, LH; McCrodden, JM; Shaw, SG; Stuart, ET; Tipton, KF; Wheatley, AM; Zhao, D1
Yu, PH; Zuo, D1
Haapalinna, A; Heinonen, E; Hervonen, A; Salonen, T; Suhonen, J1
Felten, DL; Felten, SY; ThyagaRajan, S1
Gentsch, C; Spooren, WP; Waldmeier, P1
Chesnut, MD; Dwoskin, LP; Geddes, JW; Jakel, RJ; Maragos, WF1
Hengerer, B; Spooren, WP; Waldmeier, PC1
Casas, M; Pérez, V; Prat, G; Rubi, A; Unzeta, M1
Maruyama, W; Naoi, M1
Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Tomás-Camardiel, M1
Carlsson, T; Chiu, WH; Depboylu, C; Höglinger, GU; Oertel, WH; Ries, V1
Alken, RG; Feltmann, K; Konradsson-Geuken, Å; Malmlöf, T; Schilström, B; Schneider, F; Svensson, TH1
Hoshino, N; Ishikawa, T; Muraoka, S; Nishimura, T; Okano, M; Satoyoshi, H; Takahata, K; Tsunekawa, H1

Other Studies

26 other study(ies) available for selegiline and oxidopamine

ArticleYear
Forward chemical genetic approach identifies new role for GAPDH in insulin signaling.
    Nature chemical biology, 2007, Volume: 3, Issue:1

    Topics: Adipocytes; Animals; Caenorhabditis elegans; Cell Line; Cells, Cultured; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Insulin; Molecular Structure; Phosphatidylinositols; Signal Transduction

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
In vivo labelling and axonal transport of monoamine oxidase in the rat basal ganglia using radioactive pargyline.
    Journal of neural transmission, 1986, Volume: 66, Issue:1

    Topics: Animals; Axonal Transport; Basal Ganglia; Clorgyline; Corpus Striatum; Female; Hydroxydopamines; Kainic Acid; Male; Monoamine Oxidase; Oxidopamine; Pargyline; Premedication; Rats; Rats, Inbred Strains; Selegiline; Substantia Nigra

1986
Lesion-induced reductions in trace amine accumulation: dependence on MAO inhibitor pretreatment.
    Brain research bulletin, 1989, Volume: 22, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Selegiline; Substantia Nigra; Tryptamines

1989
Selective inhibition of monoamine oxidase type B by MDL 72145 increases the central effects of L-dopa without modifying its cardiovascular effects.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: Allylamine; Amines; Animals; Blood Pressure; Brain; Decerebrate State; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Hydroxydopamines; Levodopa; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Rats; Rats, Inbred Strains; Selegiline

1986
Depletion of striatal beta-phenylethylamine following dopamine but not 5-HT denervation.
    Brain research bulletin, 1986, Volume: 17, Issue:4

    Topics: Animals; Biogenic Amines; Corpus Striatum; Denervation; Dopamine; Hydroxydopamines; Hypothalamus; Male; Oxidopamine; Phenethylamines; Raphe Nuclei; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Substantia Nigra

1986
The pharmacology of (-)deprenyl.
    Journal of neural transmission. Supplementum, 1986, Volume: 22

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcholine; Aging; Animals; Catecholamines; Corpus Striatum; Dopamine; Humans; Hydroxydopamines; In Vitro Techniques; Monoamine Oxidase; Oxidopamine; Phenethylamines; Pyridines; Selegiline

1986
The functional consequences of inhibition of monoamine oxidase type B: comparison of the pharmacological properties of L-deprenyl and MDL 72145.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:2-3

    Topics: Allylamine; Amines; Animals; Body Temperature; Brain; Electric Stimulation; Hemodynamics; Hydroxydopamines; Male; Mice; Monoamine Oxidase Inhibitors; Motor Activity; Norepinephrine; Oxidopamine; Phenethylamines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Spinal Cord; Sympathectomy, Chemical; Sympathetic Nervous System; Tyramine

1985
Potentiation by deprenil of 1-dopa induced circling in nigral-lesioned rats.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:1

    Topics: Animals; Clorgyline; Dopamine; Humans; Hydroxydopamines; Isomerism; Levodopa; Male; Oxidopamine; Phenethylamines; Rats; Rats, Inbred Strains; Selegiline; Stereotyped Behavior; Substantia Nigra

1981
Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Indans; Levodopa; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline; Substantia Nigra

1995
Chronic treatment with levodopa and/or selegiline does not affect behavioral recovery induced by fetal ventral mesencephalic grafts in unilaterally 6-hydroxydopamine-lesioned rats.
    Experimental neurology, 1994, Volume: 130, Issue:2

    Topics: Animals; Behavior, Animal; Fetal Tissue Transplantation; Levodopa; Male; Mesencephalon; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Selegiline; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase

1994
L-3,4-dihydroxyphenylalanine-induced dopamine release in the striatum of intact and 6-hydroxydopamine-treated rats: differential effects of monoamine oxidase A and B inhibitors.
    Journal of neurochemistry, 1994, Volume: 63, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Levodopa; Male; Monoamine Oxidase Inhibitors; Nerve Endings; Oxidopamine; Picolinic Acids; Rats; Rats, Sprague-Dawley; Selegiline

1994
The effects of 6-hydroxydopamine and oxidative stress on the level of brain metallothionein.
    Neurochemistry international, 1993, Volume: 23, Issue:6

    Topics: Animals; Brain; Dopamine; Drug Combinations; Humans; Male; Metallothionein; Oxidopamine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Selegiline; Sulfates; Tissue Distribution; Tumor Cells, Cultured; Zinc Compounds; Zinc Sulfate

1993
Effect of orthotopic liver transplantation and chemical denervation of the liver on the activities of hepatic monoamine oxidase and catechol-O-methyltransferase.
    Transplantation, 1993, Volume: 56, Issue:1

    Topics: Animals; Catechol O-Methyltransferase; Clorgyline; Isoenzymes; Liver; Liver Transplantation; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Lew; Reference Values; Selegiline; Substrate Specificity; Sympathectomy, Chemical

1993
Increase of survival of dopaminergic neuroblastoma in co-cultures with C-6 glioma by R-(-)-deprenyl.
    Progress in brain research, 1995, Volume: 106

    Topics: Brain Neoplasms; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Glioma; Humans; Neuroblastoma; Oxidopamine; Selegiline; Tumor Cells, Cultured

1995
Monoamine oxidase B inhibitor selegiline protects young and aged rat peripheral sympathetic neurons against 6-hydroxydopamine-induced neurotoxicity.
    Acta neuropathologica, 1996, Volume: 91, Issue:5

    Topics: Aging; Animals; Immunohistochemistry; Male; Microscopy, Fluorescence; Monoamine Oxidase Inhibitors; Oxidopamine; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Selegiline; Superior Cervical Ganglion; Tyrosine 3-Monooxygenase

1996
Restoration of sympathetic noradrenergic nerve fibers in the spleen by low doses of L-deprenyl treatment in young sympathectomized and old Fischer 344 rats.
    Journal of neuroimmunology, 1998, Volume: 81, Issue:1-2

    Topics: Adrenergic Fibers; Aging; Animals; Immunity, Cellular; Male; Monoamine Oxidase Inhibitors; Nerve Regeneration; Nerve Tissue Proteins; Neuropeptide Y; Norepinephrine; Oxidopamine; Rats; Rats, Inbred F344; Selegiline; Spleen; Sympathectomy, Chemical; Tyrosine 3-Monooxygenase

1998
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:9-10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline

1999
Does dopamine contribute to striatal damage caused by impaired mitochondrial function?
    Annals of the New York Academy of Sciences, 1999, Volume: 893

    Topics: Animals; Apomorphine; Biological Transport; Clorgyline; Corpus Striatum; Dopamine; Malonates; Medial Forebrain Bundle; Mitochondria; Monoamine Oxidase Inhibitors; Nitro Compounds; Oxidopamine; Propionates; Rats; Selegiline; Substantia Nigra

1999
CGP 3466 protects dopaminergic neurons in lesion models of Parkinson's disease.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Brain; Cell Culture Techniques; Cell Death; Disease Models, Animal; Dopamine; Female; Liver; Mesencephalon; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Oxepins; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Selegiline; Substantia Nigra; Tritium; Tyrosine 3-Monooxygenase

2000
The novel type B MAO inhibitor PF9601N enhances the duration of L-DOPA-induced contralateral turning in 6-hydroxydopamine lesioned rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:4

    Topics: Adrenergic Agents; Animals; Clorgyline; Corpus Striatum; Dopamine Agents; Dopamine Uptake Inhibitors; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidopamine; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Selegiline; Substantia Nigra

2000
Future of neuroprotection in Parkinson's disease.
    Parkinsonism & related disorders, 2001, Volume: 8, Issue:2

    Topics: Apoptosis; Humans; Molsidomine; Neuroprotective Agents; Neurotoxins; Nitric Oxide Donors; Oxidopamine; Parkinson Disease; Propylamines; Salsoline Alkaloids; Selegiline; Tetrahydroisoquinolines; Tumor Cells, Cultured

2001
Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.
    Brain research. Molecular brain research, 2005, Nov-18, Volume: 141, Issue:1

    Topics: Animals; Antiparkinson Agents; Biomarkers; Calbindins; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Situ Hybridization; Isoenzymes; Neurons; Oxidopamine; Parvalbumins; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D2; S100 Calcium Binding Protein G; Selegiline; Sympatholytics; Tyrosine 3-Monooxygenase

2005
Selegiline normalizes, while l-DOPA sustains the increased number of dopamine neurons in the olfactory bulb in a 6-OHDA mouse model of Parkinson's disease.
    Neuropharmacology, 2014, Volume: 79

    Topics: Animals; Antiparkinson Agents; Cell Count; Cell Survival; Dopamine Agents; Dopaminergic Neurons; Hippocampus; Levodopa; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Olfactory Bulb; Oxidopamine; Parkinsonian Disorders; Selegiline

2014
Deuterium-substituted L-DOPA displays increased behavioral potency and dopamine output in an animal model of Parkinson's disease: comparison with the effects produced by L-DOPA and an MAO-B inhibitor.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:2

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Brain; Deuterium; Disease Models, Animal; Dopamine; Forelimb; Levodopa; Male; Microdialysis; Monoamine Oxidase Inhibitors; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Selegiline; Tyrosine 3-Monooxygenase

2015
Selegiline increases on time without exacerbation of dyskinesia in 6-hydroxydopamine-lesioned rats displaying l-Dopa-induced wearing-off and abnormal involuntary movements.
    Behavioural brain research, 2018, 07-16, Volume: 347

    Topics: Animals; Antiparkinson Agents; Benserazide; Cytoskeletal Proteins; Disease Models, Animal; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Enkephalins; Levodopa; Male; Movement; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats, Sprague-Dawley; RNA, Messenger; Selegiline; Time Factors

2018