Compounds > selegiline

Page last updated: 2024-08-23

selegiline and nortriptyline

selegiline has been researched along with nortriptyline in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (11.11)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (61.11)	29.6817
2010's	5 (27.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM	1
Topliss, JG; Yoshida, F	1
Dansette, PM; Fontana, E; Poli, SM	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Gozalbes, R; Pineda-Lucena, A	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Asnis, GM; Endicott, J; Halbreich, U; Nathan, RS; Novacenko, H; Ostrow, L; Sachar, EJ	1
Hillier, CE; Hinds, NP; Wiles, CM	1
Kusumoto, H; Minami, A; Shimazu, S; Yoneda, F	1

Reviews

2 review(s) available for selegiline and nortriptyline

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

16 other study(ies) available for selegiline and nortriptyline

Article	Year
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents. Journal of medicinal chemistry, 1988, Volume: 31, Issue:6 Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles	1988
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery. Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19 Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats	2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
The dexamethasone suppression test in depressive illness: clinical correlates. Psychoneuroendocrinology, 1982, Volume: 7, Issue:4 Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxepin; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Male; Mianserin; Middle Aged; Nortriptyline; Phenelzine; Psychiatric Status Rating Scales; Selegiline	1982
Possible serotonin syndrome arising from an interaction between nortriptyline and selegiline in a lady with parkinsonism. Journal of neurology, 2000, Volume: 247, Issue:10 Topics: Antidepressive Agents, Tricyclic; Antiparkinson Agents; Depressive Disorder; Drug Interactions; Female; Humans; Middle Aged; Nortriptyline; Parkinson Disease; Selegiline; Serotonin Syndrome	2000
Antidepressant-like effects of selegiline in the forced swim test. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:5 Topics: Animals; Antidepressive Agents; Male; Mice; Mice, Inbred Strains; Monoamine Oxidase Inhibitors; Motor Activity; Nortriptyline; Selegiline; Swimming	2005