Page last updated: 2024-08-23

selegiline and nomifensine

selegiline has been researched along with nomifensine in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (34.78)	18.7374
1990's	8 (34.78)	18.2507
2000's	5 (21.74)	29.6817
2010's	2 (8.70)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kaakkola, S; Wurtman, RJ	1
Männistö, PT; Törnwall, M	1
Duchemin, AM; Gudehithlu, KP; Hadjiconstantinou, M; Neff, NH; Tejwani, GA	1
Arbuthnott, GW; Butcher, SP; Fairbrother, IS; Kelly, JS	1
Arai, Y; Kinemuchi, H; Kisara, K; Matsumura, T; Sakuma, I; Satoh, N; Tadano, T	1
Bizière, K; Kan, JP; Roncucci, R; Wermuth, CG; Worms, P	1
Cole, JO	1
Mihatsch, W; Przuntek, H; Russ, H	1
Leenders, KL	1
Larsson, BS; Lindquist, NG; Lydén-Sokolowski, A	1
Agnoli, A; Baldassarre, M; D'Urso, R; Del Roscio, S; Falaschi, P; Frajese, G; Mearelli, S; Rocco, A; Ruggieri, S	1
Azzaro, AJ; Schoepp, DD	1
Holdup, D; Liptrot, J; Phillipson, O	1
Bernardi, G; Bonci, A; Mercuri, NB; Scarponi, M; Siniscalchi, A	1
Cano, J; Machado, A; Rodríguez-Gómez, JA; Romero-Ramos, M; Venero, JL	1
Ali, SF; Freyaldenhoven, TE; Schmued, LC	1
Baranowski, TC; Blavo, DO; Cato, C; Doan, TN; McKinley, ET; Rubinstein, AL	1
Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Navarro, A; Santiago, M; Tomás-Camardiel, M; Villarán, RF	1

Reviews

1 review(s) available for selegiline and nomifensine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for selegiline and nomifensine

Article	Year
Where are those new antidepressants we were promised? Archives of general psychiatry, 1988, Volume: 45, Issue:2 Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Humans; Legislation, Drug; Mianserin; Nomifensine; Propiophenones; Selegiline; United States; United States Food and Drug Administration	1988

Other Studies

21 other study(ies) available for selegiline and nomifensine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study. Brain research, 1992, Aug-07, Volume: 587, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nitriles; Nitrophenols; Nomifensine; Rats; Rats, Inbred Strains; Selegiline; Tolcapone	1992
Acute toxicity of three new selective COMT inhibitors in mice with special emphasis on interactions with drugs increasing catecholaminergic neurotransmission. Pharmacology & toxicology, 1991, Volume: 69, Issue:1 Topics: Amphetamine; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Clorgyline; Convulsants; Desipramine; Drug Interactions; Lethal Dose 50; Levodopa; Male; Mice; Motor Activity; Nitriles; Nomifensine; Pentanones; Selegiline; Synaptic Transmission; Yohimbine	1991
Preproenkephalin mRNA and methionine-enkephalin increase in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment. Journal of neurochemistry, 1991, Volume: 56, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; G(M1) Ganglioside; Immunologic Techniques; Male; Mice; Mice, Inbred Strains; Nomifensine; Protein Precursors; RNA, Messenger; Selegiline	1991
Effects of selective monoamine oxidase inhibitors on the in vivo release and metabolism of dopamine in the rat striatum. Journal of neurochemistry, 1990, Volume: 55, Issue:3 Topics: Amphetamine; Animals; Catecholamines; Clorgyline; Corpus Striatum; Dopamine; Monoamine Oxidase Inhibitors; Nomifensine; Pargyline; Potassium; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Veratrine	1990
Behavioral and biochemical changes following acute administration of MPTP and MPP+. Life sciences, 1987, Mar-30, Volume: 40, Issue:13 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Nomifensine; Pyridines; Pyridinium Compounds; Selegiline; Serotonin	1987
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Body Temperature; Catalepsy; Clorgyline; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Nomifensine; Oxotremorine; Pargyline; Piperidines; Pyridazines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stereotyped Behavior	1987
Intracerebroventricular administration of 1-methyl-4-phenylpyridinium ion in mice: effects of simultaneously administered nomifensine, deprenyl, and 1-t-butyl-4,4-diphenylpiperidine. Journal of neural transmission, 1988, Volume: 71, Issue:3 Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain; Catecholamines; Caudate Nucleus; Dose-Response Relationship, Drug; Drug Interactions; Female; Injections, Intraventricular; Male; Monoamine Oxidase Inhibitors; Movement Disorders; Nomifensine; Phenethylamines; Piperidines; Pyridinium Compounds; Selegiline; Serotonin	1988
Parkinson's disease and PET tracer studies. Journal of neural transmission. Supplementum, 1988, Volume: 27 Topics: Animals; Carbon Radioisotopes; Cerebrovascular Circulation; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Energy Metabolism; Fluorine Radioisotopes; Humans; Ligands; Nomifensine; Parkinson Disease; Receptors, Dopamine; Selegiline; Spiperone; Tomography, Emission-Computed	1988
Disposition of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice before and after monoamine oxidase and catecholamine reuptake inhibition. Pharmacology & toxicology, 1988, Volume: 63, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenal Glands; Animals; Autoradiography; Brain; Catecholamines; Clorgyline; Female; Image Processing, Computer-Assisted; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Nomifensine; Pargyline; Pyridines; Scintillation Counting; Selegiline; Tissue Distribution	1988
Presynaptic neuron and postsynaptic dopamine receptor function in long term treatment of Parkinson's disease: a neuroendocrine study. Progress in clinical and biological research, 1980, Volume: 39 Topics: Aged; Apomorphine; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Levodopa; Male; Middle Aged; Nomifensine; Parkinson Disease; Prolactin; Receptors, Dopamine; Selegiline; Tremor	1980
Role of type A and type B monoamine oxidase in the metabolism of released [3H]dopamine from rat striatal slices. Biochemical pharmacology, 1982, Sep-15, Volume: 31, Issue:18 Topics: Animals; Clorgyline; Corpus Striatum; Dopamine; Male; Monoamine Oxidase; Nomifensine; Potassium; Rats; Rats, Inbred Strains; Selegiline	1982
1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol inhibits tyrosine hydroxylase activity in rat striatal synaptosomes. Journal of neural transmission. General section, 1994, Volume: 96, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biopterins; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Dopamine; Isoquinolines; Monoamine Oxidase; NAD; Nerve Tissue Proteins; Nomifensine; Parkinson Disease; Rats; Selegiline; Sulpiride; Synaptosomes; Tyrosine 3-Monooxygenase	1994
Monoamine oxidase inhibition causes a long-term prolongation of the dopamine-induced responses in rat midbrain dopaminergic cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Apr-01, Volume: 17, Issue:7 Topics: Amphetamine; Animals; Clorgyline; Cocaine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Isoenzymes; Membrane Potentials; Mesencephalon; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Nomifensine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Selegiline; Sulpiride	1997
Chronic inhibition of the high-affinity dopamine uptake system increases oxidative damage to proteins in the aged rat substantia nigra. Free radical biology & medicine, 1997, Volume: 23, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Blotting, Western; Dopamine; Dopamine Uptake Inhibitors; Free Radicals; Male; Nomifensine; Oxidative Stress; Proteins; Rats; Rats, Wistar; Selegiline; Substantia Nigra; Tyrosine 3-Monooxygenase	1997
Systemic administration of MPTP induces thalamic neuronal degeneration in mice. Brain research, 1997, Jun-06, Volume: 759, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dizocilpine Maleate; Dopamine Agents; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Neurons; Neuroprotective Agents; Nomifensine; Selegiline; Substantia Nigra; Temperature; Thalamus	1997
Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons. Brain research. Molecular brain research, 2005, Nov-30, Volume: 141, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gene Targeting; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; MPTP Poisoning; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nomifensine; Oligodeoxyribonucleotides, Antisense; Selegiline; Species Specificity; Swimming; Tyrosine 3-Monooxygenase; Zebrafish	2005
Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production. Neurotoxicology, 2008, Volume: 29, Issue:2 Topics: alpha-Methyltyrosine; Animals; Apoptosis; Astrocytes; Cell Respiration; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Microglia; Mitochondria; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neurons; Nitro Compounds; Nomifensine; Oxygen Consumption; Propionates; Rats; Rats, Wistar; Reactive Oxygen Species; Reserpine; Selegiline; Succinate Dehydrogenase; Superoxides; Synaptosomes; Tyrosine 3-Monooxygenase; Up-Regulation	2008