selegiline has been researched along with nicotine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Alexoff, D; Cilento, R; Fowler, JS; Logan, J; MacGregor, R; Pappas, N; Schlyer, D; Shea, C; Volkow, ND; Wang, GJ; Warner, D; Wolf, AP; Zezulkova, I | 1 |
| Cavalletti, M; Corsini, GU; Fascetti, F; Fornai, F; Tedeschi, D; Vaglini, F | 1 |
| Alexoff, D; Cilento, R; Fowler, JS; Logan, J; MacGregor, R; Pappas, N; Volkow, ND; Wang, GJ; Warner, D; Wolf, AP; Zezulkova, I | 1 |
| Fowler, JS; Garza, V; Gatley, SJ; King, P; Logan, J; MacGregor, R; Pappas, N; Shea, C; Volkow, ND | 1 |
| Chen, A; Cumming, P; Dagher, A; Deep, P; Gjedde, A; Kapczinski, F; Reutens, D; Wong, DF; Yokoi, F | 1 |
| Fowler, JS; Franceschi, D; Garza, V; Logan, J; MacGregor, RR; Pappas, N; Shea, C; Volkow, ND; Wang, GJ | 1 |
| Biberman, R; Gerber, Y; Katzir, I; Neumann, R | 1 |
| Chait, A; de Beaurepaire, R; Molimard, R; Rat, P; Touiki, K | 1 |
| Agnihotri, N; Mothersill, C; Poon, RC; Seymour, C | 1 |
| Belluzzi, JD; Franke, RM; Leslie, FM | 1 |
| Siu, EC; Tyndale, RF | 1 |
| Bergfors, A; Gillberg, PG; Marutle, A; Nennesmo, I; Ni, R; Nordberg, A; Voytenko, L; Yu, W | 1 |
| Barclay, E; Goyarzu, P; Magallanes, N; Malin, DH; Mathews, H; Mills, WR; Moon, WD; Negrete, AP; Stephens, B; Vela, AJ | 1 |
1 review(s) available for selegiline and nicotine
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
1 trial(s) available for selegiline and nicotine
| Article | Year |
|---|---|
A randomized controlled trial of oral selegiline plus nicotine skin patch compared with placebo plus nicotine skin patch for smoking cessation.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nicotine; Selegiline; Smoking Cessation | 2003 |
22 other study(ies) available for selegiline and nicotine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Inhibition of monoamine oxidase B in the brains of smokers.
Topics: Adult; Aged; Aged, 80 and over; Brain; Dopamine; Female; Glucose; Humans; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Selegiline; Smoking; Tomography, Emission-Computed | 1996 |
Striatal MPP+ levels do not necessarily correlate with striatal dopamine levels after MPTP treatment in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetaldehyde; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Ditiocarb; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nicotine; Piperazines; Selegiline; Serotonin | 1996 |
Neuropharmacological actions of cigarette smoke: brain monoamine oxidase B (MAO B) inhibition.
Topics: Adult; Basal Ganglia; Brain; Carbon Radioisotopes; Deuterium; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Selegiline; Smoke; Smoking; Tomography, Emission-Computed | 1998 |
An acute dose of nicotine does not inhibit MAO B in baboon brain in vivo.
Topics: Animals; Brain; Carbon Radioisotopes; Female; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Papio; Selegiline; Tomography, Emission-Computed | 1998 |
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
Topics: Benzazepines; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine; Dihydroxyphenylalanine; Dopamine Antagonists; Drug Interactions; Fluorine Radioisotopes; Humans; Nicotine; Raclopride; Radiopharmaceuticals; Selegiline; Tomography, Emission-Computed | 1999 |
Smoking a single cigarette does not produce a measurable reduction in brain MAO B in non-smokers.
Topics: Adult; Brain; Carbon Radioisotopes; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Selegiline; Smoking; Tomography, Emission-Computed | 1999 |
Harmane inhibits serotonergic dorsal raphe neurons in the rat.
Topics: Action Potentials; Analysis of Variance; Animals; Carbolines; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Harmine; Male; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Oxazoles; Phenethylamines; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists | 2005 |
Bystander effects of ionizing radiation can be modulated by signaling amines.
Topics: Animals; Apoptosis; Bystander Effect; Calcium; Cell Line; Gamma Rays; Glycine; Humans; Levodopa; Mice; Mice, Inbred C57BL; Nicotine; Oncorhynchus mykiss; Receptors, Serotonin, 5-HT3; Selegiline; Serotonin; Signal Transduction; Skin; Urinary Bladder | 2007 |
Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Clorgyline; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Factor Analysis, Statistical; Female; Infusion Pumps, Implantable; Injections, Intraperitoneal; Monoamine Oxidase Inhibitors; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selegiline; Sensory Thresholds; Time Factors; Vasoconstrictor Agents | 2007 |
Selegiline is a mechanism-based inactivator of CYP2A6 inhibiting nicotine metabolism in humans and mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Humans; Male; Metabolic Clearance Rate; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Selegiline | 2008 |
³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Astrocytes; Autoradiography; Benzothiazoles; Bungarotoxins; Cerebral Cortex; Female; Hippocampus; Humans; Immunohistochemistry; Isoquinolines; Isotope Labeling; Male; Nicotine; Parasympathetic Nervous System; Radionuclide Imaging; Receptors, Nicotinic; Selegiline; Synaptic Transmission; Thiazoles | 2013 |
Inhibition of monoamine oxidase isoforms modulates nicotine withdrawal syndrome in the rat.
Topics: Animals; Brain; Clorgyline; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Rats; Rats, Sprague-Dawley; Selegiline; Smoking Cessation; Substance Withdrawal Syndrome | 2013 |