Page last updated: 2024-08-23

selegiline and morphine

selegiline has been researched along with morphine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's3 (17.65)18.2507
2000's8 (47.06)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arnaldos, JD; Cremades, A; Milanés, MV; Vargas, ML1
Cerza, RF1
Demuth, M; Götz, ME; Koutsilieri, E; Riederer, P; Sauer, U; Sopper, S; ter Meulen, V1
Ghosh, S; Grasing, K1
Grasing, K; He, S; Li, N1
Grasing, K; He, S2
Chauhan, A; Chen, KC; Conant, K; Cutler, R; Gairola, C; Gartner, S; Haughey, N; Hauser, KF; Jie, C; Liu, Y; Mattson, MP; McArthur, JC; Nath, A; Pardo, C; Peng, X; Reid, R; Sacktor, N; Turchan-Cholewo, J1
Charkhpour, M; Ghaderi, M; Habibi-asl, B; Hassanzadeh, K; Parvizpour, A; Shakhsi, M1

Reviews

1 review(s) available for selegiline and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for selegiline and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effect of selective monoamine oxidase inhibitors on the morphine-induced hypothermia in restrained rats.
    General pharmacology, 1987, Volume: 18, Issue:2

    Topics: Animals; Body Temperature; Clorgyline; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Phenethylamines; Rats; Rats, Inbred Strains; Selegiline

1987
Beta-selective monoamine oxidase inhibitors and cardiac anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Aortic Valve; Coronary Artery Bypass; Drug Interactions; Etomidate; Female; Heart Valve Prosthesis; Humans; Hydromorphone; Hypnotics and Sedatives; Lorazepam; Monoamine Oxidase Inhibitors; Morphine; Selegiline

1995
Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.
    Journal of neurovirology, 1997, Volume: 3, Issue:5

    Topics: AIDS Dementia Complex; Carrier Proteins; Cell Survival; Cells, Cultured; Cocaine; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glutathione; HIV-1; Humans; Macrophages; Membrane Glycoproteins; Membrane Transport Proteins; Morphine; Narcotics; Nerve Tissue Proteins; Oxidative Stress; Selegiline; Substance-Related Disorders; Tumor Cells, Cultured; Up-Regulation

1997
Selegiline prevents long-term changes in dopamine efflux and stress immobility during the second and third weeks of abstinence following opiate withdrawal.
    Neuropharmacology, 1998, Volume: 37, Issue:8

    Topics: Animals; Dopamine; Male; Morphine; Rats; Rats, Wistar; Restraint, Physical; Selegiline; Stress, Physiological; Substance Withdrawal Syndrome

1998
Selegiline modifies the extinction of responding following morphine self-administration, but does not alter cue-induced reinstatement, reacquisition of morphine reinforcement, or precipitated withdrawal.
    Pharmacological research, 2005, Volume: 51, Issue:1

    Topics: Animals; Cues; Extinction, Psychological; Male; Morphine; Rats; Rats, Wistar; Reinforcement, Psychology; Selegiline; Self Administration; Substance Withdrawal Syndrome

2005
Effects of high-dose selegiline on morphine reinforcement and precipitated withdrawal in dependent rats.
    Behavioural pharmacology, 2005, Volume: 16, Issue:1

    Topics: Acoustic Stimulation; Analgesics, Opioid; Animals; Conditioning, Operant; Cues; Dopamine; Eating; Male; Monoamine Oxidase Inhibitors; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Photic Stimulation; Rats; Rats, Wistar; Reinforcement Schedule; Reinforcement, Psychology; Selegiline; Self Administration; Substance Withdrawal Syndrome

2005
Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.
    Neurobiology of disease, 2006, Volume: 23, Issue:1

    Topics: Adult; AIDS Dementia Complex; Antioxidants; Apolipoprotein E4; Apolipoproteins E; Cells, Cultured; Coculture Techniques; Diosgenin; Gene Expression; Gene Products, tat; Genetic Predisposition to Disease; HIV; HIV Envelope Protein gp120; HIV Infections; Humans; Male; Membrane Potentials; Mitochondria; Morphine; Narcotics; Neurons; Neuroprotective Agents; Neurotoxins; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Polymerase Chain Reaction; Reactive Oxygen Species; Selegiline; tat Gene Products, Human Immunodeficiency Virus; Viral Proteins

2006
L-methamphetamine and selective MAO inhibitors decrease morphine-reinforced and non-reinforced behavior in rats; Insights towards selegiline's mechanism of action.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 85, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Clorgyline; Conditioning, Operant; Extinction, Psychological; Indans; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Morphine; Morphine Dependence; Rats; Rats, Wistar; Reinforcement, Psychology; Selegiline; Self Administration; Substance Withdrawal Syndrome

2006
Repeated central administration of selegiline attenuated morphine physical dependence in rat.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:3

    Topics: Animals; Infusions, Intraventricular; Male; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Sprague-Dawley; Rats, Wistar; Selegiline; Substance Withdrawal Syndrome; Substance-Related Disorders

2013