Page last updated: 2024-08-23

selegiline and moclobemide

selegiline has been researched along with moclobemide in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (9.21)	18.7374
1990's	12 (15.79)	18.2507
2000's	20 (26.32)	29.6817
2010's	34 (44.74)	24.3611
2020's	3 (3.95)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Agostinelli, E; Artico, M; Befani, O; De Martino, G; La Regina, G; Palumbo, M; Silvestri, R; Turini, P	1
Agostinelli, E; Artico, M; Befani, O; Cirilli, R; Costi, R; Di Santo, R; Ferretti, R; Gallinella, B; La Torre, F; Meninno, T; Palmegiani, P; Roux, A; Turini, P	1
Agostinelli, E; Artico, M; Befani, O; La Regina, G; Lavecchia, A; Novellino, E; Silvestri, R; Turini, P	1
Alcaro, S; Befani, O; Bolasco, A; Chimenti, F; Chimenti, P; Fioravanti, R; Manna, F; Ortuso, F; Secci, D; Turini, P	1
Alcaro, S; Bolasco, A; Cardia, MC; Chimenti, F; Chimenti, P; Fioravanti, R; Manna, F; Ortuso, F; Rossi, F; Secci, D; Turini, P	1
Lombardo, F; Obach, RS; Waters, NJ	1
Alcaro, S; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Ferretti, R; Granese, A; La Torre, F; Maccioni, E; Orallo, F; Ortuso, F; Secci, D; Yáñez, M	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Agostinelli, E; Befani, O; Gatti, V; La Regina, G; Lavecchia, A; Novellino, E; Silvestri, R; Turini, P	1
Ercan, A; Jayaprakash, V; Sinha, BN; Ucar, G	1
Erol, K; Gökhan-Kelekçi, N; Kendi, E; Koyunoğlu, S; Ozgen, O; Uçar, G; Yabanoğlu, S; Yelekçi, K; Yeşilada, A	1
Alcaro, S; Bizzarri, B; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Ortuso, F; Secci, D; Yáñez, M	1
Alcaro, S; Bolasco, A; Chimenti, F; Chimenti, P; Fioravanti, R; Orallo, F; Ortuso, F; Rossi, F; Secci, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Bilgin, AA; Ercan, A; Gökhan-Kelekçi, N; Işik, S; Sahin, ZS; Simşek, OO; Uçar, G; Yelekçi, K	1
Bizzarri, B; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Secci, D; Yáñez, M	1
Basu, A; Jayaprakash, V; Sahoo, A; Sinha, BN; Ucar, G; Yabanoglu, S	1
Alcaro, S; Bolasco, A; Chimenti, F; Chimenti, P; Cirilli, R; Ferretti, R; Fioravanti, R; Orallo, F; Ortuso, F; Rossi, F; Sanna, ML; Secci, D; Yáñez, M	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Basu, A; Jayaprakash, V; Karuppasamy, M; Kulandaivelu, U; Mahapatra, M; Mishra, N; Sharon, A; Sinha, BN; Ucar, G; Yabanoglu, S	1
Alcaro, S; Borges, F; Gaspar, A; Milhazes, N; Orallo, F; Ortuso, F; Uriarte, E; Yáñez, M	1
Alcaro, S; Bolasco, A; Cardia, MC; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Distinto, S; Ferretti, R; Granese, A; Kirchmair, J; Langer, T; Maccioni, E; Orallo, F; Ortuso, F; Secci, D; Yáñez, M	1
Alcaro, S; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Ortuso, F; Secci, D; Yáñez, M	1
Alcaro, S; Cardia, MC; Costa, G; Distinto, S; Maccioni, E; Meleddu, R; Orallo, F; Sanna, ML; Secci, D; Vigo, S; Yanez, M	1
Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Gallinella, B; Granese, A; Orallo, F; Sanna, ML; Secci, D; Yáñez, M	1
Alcaro, S; Bolasco, A; Fioravanti, R; Manna, F; Orallo, F; Ortuso, F; Rossi, F; Vitali, A; Yáñez, M	1
Alcaro, S; Bolasco, A; Desideri, N; Fioravanti, R; Monaco, LP; Orallo, F; Ortuso, F; Yáñez, M	1
Basu, A; Behera, J; Ercan, A; Jagrat, M; Jayaprakash, V; Sankaran, V; Sinha, BN; Ucar, G; Yabanoglu, S	1
Alcaro, S; Bolasco, A; Carradori, S; Chimenti, P; Ortuso, F; Secci, D; Yáñez, M	1
Escobar, M; García-Mera, X; González-Díaz, H; Prado-Prado, F; Riera-Fernandez, P; Sobarzo-Sánchez, E; Yañez, M	1
Alcaro, S; Bolasco, A; Cardia, MC; Distinto, S; Gaspari, M; Kirchmair, J; Maccioni, E; Markt, P; Meleddu, R; Ortuso, F; Sanna, ML; Secci, D; Wolber, G; Yáñez, M	1
Pettersson, F; Sonesson, C; Svensson, P; Waters, N; Waters, S	1
Abdalla, MM; Abdelhafez, OM; Ali, HI; Amin, KM; Batran, RZ	1
Bolasco, A; Carradori, S; D'Ascenzio, M; Nescatelli, R; Secci, D; Yáñez, M	1
Alcaro, S; Biava, M; Desideri, N; Fioravanti, R; Ortuso, F; Proietti Monaco, L; Yáñez, M	2
Byun, Y; Han, MH; Hong, SH; Jung, HI; Noh, M; Park, J; Park, S	1
Biava, M; Desideri, N; Fioravanti, R; Grammatica, L; Proietti Monaco, L; Yáñez, M	1
Ciftci-Yabanoglu, S; Jadav, SS; Jagrat, M; Jayaprakash, V; Sinha, BN; Ucar, G; Vishnu Nayak, B	1
Mattsson, C; Sonesson, C; Svensson, P	1
Alcaro, S; Carradori, S; Cirilli, R; D'Ascenzio, M; De Monte, C; Mannina, L; Ortuso, F; Secci, D; Sobolev, AP; Yáñez, M	1
Bhakat, S; Ciftci-Yabanoglu, S; Jayaprakash, V; Nayak, BV; Sinha, BN; Soliman, ME; Timiri, AK; Ucar, G	1
Estrada, M; Hripcsak, G; Matos, MJ; Rodríguez-Enríquez, F; Rodríguez-Franco, MI; Santana, L; Uriarte, E; Vilar, S; Viña, D	1
Baysal, I; Mathew, B; Mathew, GE; Prakasan, A; Suresh, J; Suresh, JK; Thomas, A; Uçar, G; Vilapurathu, JK	1
Badavath, VN; Baysal, İ; Jayaprakash, V; Sinha, BN; Ucar, G	1
Estrada, M; Herrera-Arozamena, C; Morales-García, JA; Pérez, C; Pérez-Castillo, A; Rodríguez-Franco, MI; Romero, A; Viña, D	1
Atlı, Ö; Can, NÖ; Kaplancıklı, ZA; Korkut, B; Levent, S; Osmaniye, D; Özkay, Y; Sağlık, BN	1
de Andrés, L; Estrada Valencia, M; Herrera-Arozamena, C; Laurini, E; Morales-García, JA; Pérez, C; Pérez-Castillo, A; Pricl, S; Ramos, E; Rodríguez-Franco, MI; Romero, A; Viña, D; Yáñez, M	1
Borges, F; Delogu, GL; Fontenla, JA; Hripcsak, G; Matos, MJ; Mayán, L; Munín, J; Pintus, F; Vilar, S; Viña, D	1
Acar Çevik, U; Kaplancıklı, ZA; Kaya Çavuşoğlu, B; Levent, S; Osmaniye, D; Özkay, Y; Sağlık, BN	1
Dedecengiz, E; Erikci, A; Gokhan-Kelekci, N; Kaynak, FB; Salgin-Goksen, U; Tel, BC; Telli, G; Ucar, G; Yelekci, K	1
Dawbaa, S; Evren, AE; Nuha, D; Sağlık, BN; Yurttaş, L	1
Iwata, N; Kumagae, Y; Matsui, Y	1
Klimek, V; Maj, J; Nowak, G; Zak, J	1
Kaarttinen, A; Kallio, J; Koulu, M; Pyykkö, K; Scheinin, M; Vuorinen, J; Zimmer, RH	1
Rényi, L	1
Bizière, K; Kan, JP; Roncucci, R; Wermuth, CG; Worms, P	1
Bizière, K; Kan, JP; Mouget-Goniot, C; Steinberg, R; Worms, P	1
Jarrott, B; Vajda, FJ	1
Cesura, AM; Da Prada, M; Kettler, R; Richards, JG	1
Aarons, SF; Brown, RD; Frances, AJ; Mann, JJ	1
Youdim, MB	1
Dingemanse, J; Korn, A; Moritz, E; Wagner, B	1
Dingemanse, J; Kettler, R; Kneer, J; Korn, A; Koulu, M; Wallnöfer, A; Zürcher, G	1
Illi, A; Koulu, M; Ojala-Karlsson, P; Scheinin, M	1
Ballering, LA; Steur, EN	1
Mitchell, PB	1
Barros, HM; Ferigolo, M; Marquardt, AR; Tannhauser, M	1
Bitsios, P; Bradshaw, CM; Langley, RW; Pyykkö, K; Scheinin, M; Szabadi, E; Tavernor, S	1
Ballering, LA; Jansen Steur, EN	1
Hibell, A; Hudson, AL; Lalies, MD; Nutt, DJ	1
De Angelis, L; Furlan, C	1
Diksic, M; Hasegawa, S; Mück-Seler, D; Nishi, K; Watanabe, A	1
Baker, GB; Sowa, B; Todd, KG	1
Deng, JF; Wu, ML	1

Reviews

3 review(s) available for selegiline and moclobemide

Article	Year
The current status of monoamine oxidase and its inhibitors. The Medical journal of Australia, 1987, Jun-15, Volume: 146, Issue:12 Topics: Allylamine; Benzamides; Clinical Trials as Topic; Humans; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Selegiline	1987
The advent of selective monoamine oxidase A inhibitor antidepressants devoid of the cheese reaction. Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 386 Topics: Benzamides; Cheese; Clorgyline; Depressive Disorder; Humans; Hypertension; Moclobemide; Monoamine Oxidase Inhibitors; Selegiline; Tyramine	1995
Drug interactions of clinical significance with selective serotonin reuptake inhibitors. Drug safety, 1997, Volume: 17, Issue:6 Topics: Antidepressive Agents, Tricyclic; Benzamides; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Humans; Isoenzymes; Lithium; Liver; Moclobemide; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Selegiline; Sumatriptan; Tryptophan	1997

Trials

8 trial(s) available for selegiline and moclobemide

Article	Year
Inhibition of monoamine oxidase by moclobemide: effects on monoamine metabolism and secretion of anterior pituitary hormones and cortisol in healthy volunteers. British journal of clinical pharmacology, 1989, Volume: 27, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Catecholamines; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Pituitary Hormones, Anterior; Random Allocation; Selegiline; Vanilmandelic Acid	1989
The current status of monoamine oxidase and its inhibitors. The Medical journal of Australia, 1987, Jun-15, Volume: 146, Issue:12 Topics: Allylamine; Benzamides; Clinical Trials as Topic; Humans; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Selegiline	1987
Studies of selective and reversible monoamine oxidase inhibitors. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:7 Pt 2 Topics: Animals; Benzamides; Blood Platelets; Brain; Clinical Trials as Topic; Depressive Disorder; Dopamine; Double-Blind Method; Drug Interactions; Food; Humans; Male; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Panic; Phenethylamines; Phobic Disorders; Rats; Selegiline; Serotonin; Tyramine	1984
Tyramine pressor sensitivity in healthy subjects during combined treatment with moclobemide and selegiline. European journal of clinical pharmacology, 1996, Volume: 49, Issue:4 Topics: Adrenergic Agents; Adult; Analysis of Variance; Benzamides; Blood Pressure; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Food-Drug Interactions; Humans; Hypertension; Injections, Intravenous; Male; Moclobemide; Monoamine Oxidase Inhibitors; Selegiline; Tyramine	1996
Pharmacokinetic-pharmacodynamic interactions between two selective monoamine oxidase inhibitors: moclobemide and selegiline. Clinical neuropharmacology, 1996, Volume: 19, Issue:5 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Double-Blind Method; Drug Interactions; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Selegiline	1996
Moclobemide and selegeline in the treatment of depression in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 63, Issue:4 Topics: Antidepressive Agents; Benzamides; Depressive Disorder; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline	1997
Comparison of the effects of moclobemide and selegiline on tyramine-evoked mydriasis in man. British journal of clinical pharmacology, 1998, Volume: 45, Issue:6 Topics: Adult; Analysis of Variance; Benzamides; Blood Platelets; Double-Blind Method; Drug Interactions; Feasibility Studies; Humans; Male; Meiosis; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Naphthols; Propylene Glycols; Pupil; Selegiline; Tyramine	1998
Combined and selective monoamine oxidase inhibition in the treatment of depression in Parkinson's disease. Advances in neurology, 1999, Volume: 80 Topics: Adult; Aged; Benzamides; Cognition; Depression; Drug Combinations; Female; Humans; Male; Medical Records; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Movement; Parkinson Disease; Selegiline	1999

Other Studies

66 other study(ies) available for selegiline and moclobemide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B. Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6 Topics: Alkynes; Amides; Amines; Animals; Brain; Cattle; Isoenzymes; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrroles; Structure-Activity Relationship	2003
Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors. Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13 Topics: Drug Design; Kinetics; Models, Molecular; Molecular Structure; Monoamine Oxidase Inhibitors; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Structure-Activity Relationship	2005
New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity. Journal of medicinal chemistry, 2007, Mar-08, Volume: 50, Issue:5 Topics: Animals; Benzylamines; Binding Sites; Brain; Cattle; In Vitro Techniques; Isoenzymes; Mitochondria; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrroles; Stereoisomerism; Structure-Activity Relationship	2007
Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5-diaryl pyrazole inhibitors. Journal of medicinal chemistry, 2007, Feb-08, Volume: 50, Issue:3 Topics: Isoenzymes; Isomerism; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Structure-Activity Relationship	2007
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives. European journal of medicinal chemistry, 2008, Volume: 43, Issue:10 Topics: Animals; Cattle; Drug Design; Humans; Models, Molecular; Molecular Conformation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Substrate Specificity	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones. Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16 Topics: Chromatography, High Pressure Liquid; Cyclohexanones; Humans; Hydrazones; Inhibitory Concentration 50; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Thermodynamics; Thiazoles; Thiosemicarbazones	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B. Bioorganic & medicinal chemistry, 2008, Nov-15, Volume: 16, Issue:22 Topics: Binding Sites; Indoles; Kinetics; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship	2008
Pyrazoline-based mycobactin analogues as MAO-inhibitors. Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24 Topics: Acetamides; Animals; Binding Sites; Catalytic Domain; Drug Design; Humans; Inhibitory Concentration 50; Linezolid; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Pyrazoles; Rats; Siderophores	2008
New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Binding Sites; Flavin-Adenine Dinucleotide; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Quinazolinones	2009
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins. Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7 Topics: Coumarins; Crystallography, X-Ray; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship	2009
Chalcones: a valid scaffold for monoamine oxidases inhibitors. Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9 Topics: Chalcones; Crystallography, X-Ray; Databases, Protein; Drug Design; Humans; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors. Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18 Topics: Animals; Catalytic Domain; Computer Simulation; Crystallography, X-Ray; Indazoles; Mitochondria, Liver; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Rats; Structure-Activity Relationship	2009
Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives. European journal of medicinal chemistry, 2010, Volume: 45, Issue:2 Topics: Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles	2010
Towards development of selective and reversible pyrazoline based MAO-inhibitors: Synthesis, biological evaluation and docking studies. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: Animals; Binding Sites; Computer Simulation; Humans; Hydrogen Bonding; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Isoforms; Pyrazoles; Rats; Sulfonamides	2010
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorganic & medicinal chemistry, 2010, Volume: 18, Issue:3 Topics: Flavanones; Flavones; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Sulfhydryl Compounds	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies. Bioorganic & medicinal chemistry, 2010, Mar-01, Volume: 18, Issue:5 Topics: Animals; Binding Sites; Computer Simulation; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Rats; Structure-Activity Relationship	2010
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B. Bioorganic & medicinal chemistry letters, 2010, May-01, Volume: 20, Issue:9 Topics: Binding Sites; Chromones; Computer Simulation; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Isoforms	2010
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors. Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14 Topics: Chromatography, High Pressure Liquid; Humans; Hydrazones; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship; Thiazoles	2010
Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors. Bioorganic & medicinal chemistry, 2010, Aug-01, Volume: 18, Issue:15 Topics: Humans; Hydrazines; Hydrogen Peroxide; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship	2010
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase. European journal of medicinal chemistry, 2010, Volume: 45, Issue:10 Topics: Animals; Cell Line; Humans; Insecta; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Pyrazoles; Recombinant Proteins; Structure-Activity Relationship; Thioamides	2010
Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines. Journal of medicinal chemistry, 2010, Sep-09, Volume: 53, Issue:17 Topics: Chromatography, High Pressure Liquid; Cyclohexanes; Humans; Hydrazines; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Triazoles	2010
Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors. Bioorganic & medicinal chemistry letters, 2010, Nov-15, Volume: 20, Issue:22 Topics: Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Prenylation; Pyrazoles; Structure-Activity Relationship	2010
Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties. Journal of medicinal chemistry, 2011, Apr-14, Volume: 54, Issue:7 Topics: Drug Discovery; Flavonoids; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Conformation; Substrate Specificity	2011
Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies. Bioorganic & medicinal chemistry letters, 2011, Jul-15, Volume: 21, Issue:14 Topics: Binding Sites; Computer Simulation; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Pyrazoles; Structure-Activity Relationship	2011
Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. European journal of medicinal chemistry, 2011, Volume: 46, Issue:10 Topics: Coumarins; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship	2011
2D MI-DRAGON: a new predictor for protein-ligands interactions and theoretic-experimental studies of US FDA drug-target network, oxoisoaporphine inhibitors for MAO-A and human parasite proteins. European journal of medicinal chemistry, 2011, Volume: 46, Issue:12 Topics: Antiprotozoal Agents; Aporphines; Databases, Factual; Humans; Ligands; Malaria, Falciparum; Markov Chains; Models, Biological; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Plasmodium falciparum; Protozoan Proteins; Quantitative Structure-Activity Relationship; Software; United States	2011
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B. European journal of medicinal chemistry, 2012, Volume: 48 Topics: Binding Sites; Humans; Hydrazones; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Dynamics Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Protein Conformation; Structure-Activity Relationship; Tandem Mass Spectrometry; Thiazoles	2012
Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors. Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzene Derivatives; Catalytic Domain; Corpus Striatum; Dopamine; Humans; Isoenzymes; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazines; Piperidines; Rats; Structure-Activity Relationship	2012
Synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase A inhibitors. Journal of medicinal chemistry, 2012, Dec-13, Volume: 55, Issue:23 Topics: Coumarins; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Spectrophotometry, Infrared	2012
Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines. European journal of medicinal chemistry, 2012, Volume: 58 Topics: Dose-Response Relationship, Drug; Humans; Hydrazines; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship	2012
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors. European journal of medicinal chemistry, 2013, Volume: 59 Topics: Cells, Cultured; Curcumin; Enzyme Activation; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase Inhibitors; Quantum Theory; Structure-Activity Relationship	2013
The opposite effect of isotype-selective monoamine oxidase inhibitors on adipogenesis in human bone marrow mesenchymal stem cells. Bioorganic & medicinal chemistry letters, 2013, Jun-01, Volume: 23, Issue:11 Topics: 3T3-L1 Cells; Adipogenesis; Animals; Antidiuretic Agents; Bone Marrow Cells; Humans; Mesenchymal Stem Cells; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenelzine; Tranylcypromine	2013
Design, synthesis, and in vitro hMAO-B inhibitory evaluation of some 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazoles. Bioorganic & medicinal chemistry letters, 2013, Sep-15, Volume: 23, Issue:18 Topics: Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Molecular Structure; Monoamine Oxidase; Pyrazoles; Structure-Activity Relationship	2013
Monoamine oxidase inhibitory activity of 3,5-biaryl-4,5-dihydro-1H-pyrazole-1-carboxylate derivatives. European journal of medicinal chemistry, 2013, Volume: 69 Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Structure-Activity Relationship	2013
A novel series of 6-substituted 3-(pyrrolidin-1-ylmethyl)chromen-2-ones as selective monoamine oxidase (MAO) A inhibitors. European journal of medicinal chemistry, 2014, Feb-12, Volume: 73 Topics: Animals; Binding Sites; Chromones; Corpus Striatum; Humans; Microdialysis; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Protein Binding; Rats; Solubility; Structure-Activity Relationship	2014
Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors. Bioorganic & medicinal chemistry, 2014, May-15, Volume: 22, Issue:10 Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Design; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thiazoles	2014
Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones. Bioorganic chemistry, 2015, Volume: 58 Topics: Benzopyrans; Kinetics; Molecular Docking Simulation; Monoamine Oxidase Inhibitors; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization	2015
Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives. Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3 Topics: Binding Sites; Coumarins; Humans; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Selegiline; Structure-Activity Relationship	2015
Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies. Bioorganic chemistry, 2015, Volume: 62 Topics: Chalcones; Humans; Hydrocarbons, Fluorinated; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Propane	2015
Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis. ACS medicinal chemistry letters, 2016, Jan-14, Volume: 7, Issue:1 Topics:	2016
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors. European journal of medicinal chemistry, 2016, Jul-19, Volume: 117 Topics: Chromans; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Sensitivity and Specificity; Solvents; Structure-Activity Relationship	2016
New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Alzheimer Disease; Amines; Animals; Antioxidants; Cell Line, Tumor; Cholinesterases; Drug Design; Humans; Male; Mice; Molecular Targeted Therapy; Monoamine Oxidase; Neuroprotective Agents; Piperidines	2016
Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible hMAO-A inhibitors. European journal of medicinal chemistry, 2018, Jan-20, Volume: 144 Topics: Catalytic Domain; Drug Design; Humans; Hydrazines; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Thiazoles	2018
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease. European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Donepezil; Enzyme Inhibitors; Flavonoids; Humans; Indans; Lipoxygenase Inhibitors; Male; Mice, Inbred BALB C; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurogenesis; Neuroprotective Agents; Piperidines; Receptors, sigma; Sigma-1 Receptor	2018
MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, MedChemComm, 2017, Sep-01, Volume: 8, Issue:9 Topics:	2017
Novel 1,3,4-thiadiazole compounds as potential MAO-A inhibitors - design, synthesis, biological evaluation and molecular modelling. RSC medicinal chemistry, 2020, Sep-01, Volume: 11, Issue:9 Topics:	2020
New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors. Journal of medicinal chemistry, 2021, 02-25, Volume: 64, Issue:4 Topics: Animals; Antidepressive Agents; Depression; Hep G2 Cells; Humans; Hydrazones; Mice; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Pyrazoles; Structure-Activity Relationship	2021
Synthesis of novel thiazolyl hydrazone derivatives as potent dual monoamine oxidase-aromatase inhibitors. European journal of medicinal chemistry, 2022, Feb-05, Volume: 229 Topics: Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Humans; Hydrazones; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Protein Conformation; Structure-Activity Relationship	2022
Deamination of norepinephrine, dopamine, and serotonin by type A monoamine oxidase in discrete regions of the rat brain and inhibition by RS-8359. Japanese journal of pharmacology, 1991, Volume: 55, Issue:1 Topics: Animals; Benzamides; Biogenic Monoamines; Brain; Cerebral Cortex; Clorgyline; Corpus Striatum; Deamination; Dopamine; Dose-Response Relationship, Drug; Hippocampus; Male; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitriles; Norepinephrine; Pyrimidines; Rats; Rats, Inbred Strains; Selegiline; Serotonin	1991
The effect of repeated treatment with brofaromine, moclobemide and deprenyl on alpha 1-adrenergic and dopaminergic receptors in the rat brain. Neuroscience letters, 1990, Jan-01, Volume: 108, Issue:1-2 Topics: Animals; Benzamides; Brain; Male; Moclobemide; Phenethylamines; Piperidines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Selegiline	1990
The effects of monoamine oxidase inhibitors on the ejaculatory response induced by 5-methoxy-N,N-dimethyltryptamine in the rat. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: Animals; Benzamides; Clorgyline; Dose-Response Relationship, Drug; Ejaculation; Male; Methoxydimethyltryptamines; Moclobemide; Monoamine Oxidase Inhibitors; Nialamide; p-Chloroamphetamine; Pargyline; Rats; Receptors, Serotonin; Selegiline; Serotonin; Time Factors	1986
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Body Temperature; Catalepsy; Clorgyline; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Nomifensine; Oxotremorine; Pargyline; Piperidines; Pyridazines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stereotyped Behavior	1987
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. II. Biochemical characterization of monoamine oxidase inhibition. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Animals; Benzamides; Biogenic Amines; Brain; Clorgyline; Dopamine; Duodenum; Harmaline; Isoenzymes; Liver; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Pyridazines; Rats; Selegiline; Synaptosomes	1987
Reversible, enzyme-activated monoamine oxidase inhibitors: new advances. Pharmacological research communications, 1988, Volume: 20 Suppl 4 Topics: Animals; Benzamides; Brain; Clorgyline; Humans; In Vitro Techniques; Male; Moclobemide; Monoamine Oxidase Inhibitors; Phenelzine; Picolinic Acids; Piperidines; Rats; Selegiline	1988
Norepinephrine metabolites in plasma as indicators of pharmacological inhibition of monoamine oxidase and catechol O-methyltransferase. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Antiparkinson Agents; Benzamides; Biomarkers; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Humans; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitriles; Norepinephrine; Pentanones; Selegiline	1998
Comparison of behavioral effects of moclobemide and deprenyl during forced swimming. Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:2 Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzamides; Imipramine; Male; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Phenethylamines; Psychotropic Drugs; Rats; Rats, Wistar; Selegiline; Swimming	1998
Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands. Annals of the New York Academy of Sciences, 1999, Jun-21, Volume: 881 Topics: Animals; Benzamides; Binding Sites; Brain; Clorgyline; Imidazoles; Imidazoline Receptors; Isoenzymes; Kinetics; Ligands; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Rats; Receptors, Drug; Selegiline; Serotonin	1999
The anxiolytic-like properties of two selective MAOIs, moclobemide and selegiline, in a standard and an enhanced light/dark aversion test. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:4 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Convulsants; Darkness; Drug Interactions; Female; Light; Lorazepam; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Pentylenetetrazole; Selegiline	2000
Acute effects of moclobemide and deprenyl on 5-HT synthesis rates in the rat brain: An autoradiographic study. Brain research bulletin, 2006, Oct-16, Volume: 70, Issue:4-6 Topics: Animals; Autoradiography; Brain; Carbon Isotopes; Male; Moclobemide; Monoamine Oxidase Inhibitors; Radiography; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Tryptophan	2006
Amine oxidases and their inhibitors: what can they tell us about neuroprotection and the development of drugs for neuropsychiatric disorders? Journal of psychiatry & neuroscience : JPN, 2007, Volume: 32, Issue:5 Topics: Amine Oxidase (Copper-Containing); Antidepressive Agents; Humans; Mental Disorders; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Phenelzine; RNA, Messenger; Selegiline; Tranylcypromine	2007
Serotonin toxicity caused by moclobemide too soon after paroxetine-selegiline. Journal of the Chinese Medical Association : JCMA, 2009, Volume: 72, Issue:8 Topics: Female; Humans; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Paroxetine; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin	2009