Page last updated: 2024-08-23

selegiline and gamma-aminobutyric acid

selegiline has been researched along with gamma-aminobutyric acid in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Bellman, K; Knegtel, RM; Settimo, L1
Rinne, UK1
Colucci d'Amato, C; Cristillo, A; Puccini, A; Vizioli, R1
Koulu, M; Lammintausta, R1
Olpe, HR; Schellenberg, A1
Czurkó, A; Faludi, B; Karádi, Z; Knoll, J; Lénárd, L; Niedetzky, C; Vida, I1
Baker, GB; Todd, KG1
Desser, H; Gerlach, M; Riederer, P; Youdim, MB1
Commissiong, JW; Finberg, JP; Johnston, JM; Takeshima, T1
Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Tomás-Camardiel, M1
Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Navarro, A; Santiago, M; Tomás-Camardiel, M; Villarán, RF1
Cho, J; Cho, S; Cho, SJ; Choi, JW; Chun, H; Hwang, SY; Jang, BK; Jo, S; Ju, YH; Kim, HJ; Kim, J; Kim, S; Kim, SW; Lee, C; Lee, CJ; Londhe, AM; Nam, MH; Oh, SJ; Pae, AN; Park, JH; Park, KD; Park, M; Shin, SJ; Song, HJ; Woo, J; Yarishkin, O; Yeon, SK1
Gómez-Galán, M; Henning, L; Lindskog, M; Srivastava, I; Vazquez-Juarez, E1
An, H; Cho, HU; Jang, DP; Kim, S; Lee, CJ; Nam, MH; Sim, J; Yang, S1

Reviews

3 review(s) available for selegiline and gamma-aminobutyric acid

ArticleYear
Recent advances in research on Parkinsonism.
    Acta neurologica Scandinavica. Supplementum, 1978, Volume: 67

    Topics: Acetylcholinesterase; Adult; Apomorphine; Benserazide; Brain; Bromocriptine; Carbidopa; Dopa Decarboxylase; Dopamine; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Selegiline; Serotonin; Substance P; Tyrosine 3-Monooxygenase

1978
[Biochemical bases of Parkinson disease].
    Recenti progressi in medicina, 1984, Volume: 75, Issue:10

    Topics: Acetylcholine; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dopa Decarboxylase; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Selegiline; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase

1984
New horizons in molecular mechanisms underlying Parkinson's disease and in our understanding of the neuroprotective effects of selegiline.
    Journal of neural transmission. Supplementum, 1996, Volume: 48

    Topics: Binding Sites; Clinical Trials as Topic; Corpus Striatum; Disease Progression; gamma-Aminobutyric Acid; Humans; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Neurotoxins; Nootropic Agents; Oxidative Stress; Parkinson Disease; Polyamines; Receptors, N-Methyl-D-Aspartate; Selegiline; Substantia Nigra

1996

Other Studies

13 other study(ies) available for selegiline and gamma-aminobutyric acid

ArticleYear
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Human growth hormone and dopaminergic drugs, with special reference to deprenyl (selegiline): a summary of studies on volunteers.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 95

    Topics: Apomorphine; Bromocriptine; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Phenethylamines; Receptors, Dopamine; Selegiline; Synapses

1983
The sensitivity of cortical neurons to serotonin: effect of chronic treatment with antidepressants, serotonin-uptake inhibitors and monoamine-oxidase-blocking drugs.
    Journal of neural transmission, 1981, Volume: 51, Issue:3-4

    Topics: Animals; Benzofurans; Cerebral Cortex; Clomipramine; Clorgyline; Desipramine; Electric Conductivity; gamma-Aminobutyric Acid; Male; Monoamine Oxidase Inhibitors; Neurons; Piperidines; Rats; Selegiline; Serotonin; Serotonin Antagonists

1981
Responses of forebrain neurons to the MAO-B blocker L-deprenyl.
    Brain research bulletin, 1995, Volume: 36, Issue:3

    Topics: Acetylcholine; Amphetamine; Animals; Clorgyline; Electrophoresis; Female; gamma-Aminobutyric Acid; Macaca mulatta; Male; Microelectrodes; Monoamine Oxidase; Neurons; Prosencephalon; Rats; Rats, Inbred Strains; Selegiline; Species Specificity

1995
GABA-elevating effects of the antidepressant/antipanic drug phenelzine in brain: effects of pretreatment with tranylcypromine, (-)-deprenyl and clorgyline.
    Journal of affective disorders, 1995, Dec-13, Volume: 35, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Animals; Antidepressive Agents; Brain; Clorgyline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenelzine; Premedication; Rats; Rats, Sprague-Dawley; Selegiline; Tranylcypromine

1995
Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor.
    Neuroreport, 1998, Mar-09, Volume: 9, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Clorgyline; Dopamine; Embryo, Mammalian; gamma-Aminobutyric Acid; Indans; Mesencephalon; Methamphetamine; Microtubule-Associated Proteins; Monoamine Oxidase Inhibitors; Neurons; Rats; Rats, Sprague-Dawley; Selegiline; Tyrosine 3-Monooxygenase

1998
Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.
    Brain research. Molecular brain research, 2005, Nov-18, Volume: 141, Issue:1

    Topics: Animals; Antiparkinson Agents; Biomarkers; Calbindins; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Situ Hybridization; Isoenzymes; Neurons; Oxidopamine; Parvalbumins; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D2; S100 Calcium Binding Protein G; Selegiline; Sympatholytics; Tyrosine 3-Monooxygenase

2005
Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.
    Neurotoxicology, 2008, Volume: 29, Issue:2

    Topics: alpha-Methyltyrosine; Animals; Apoptosis; Astrocytes; Cell Respiration; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Microglia; Mitochondria; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neurons; Nitro Compounds; Nomifensine; Oxygen Consumption; Propionates; Rats; Rats, Wistar; Reactive Oxygen Species; Reserpine; Selegiline; Succinate Dehydrogenase; Superoxides; Synaptosomes; Tyrosine 3-Monooxygenase; Up-Regulation

2008
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease.
    Science advances, 2019, Volume: 5, Issue:3

    Topics: Alzheimer Disease; Animals; Astrocytes; Cognitive Dysfunction; D-Amino-Acid Oxidase; Enzyme Inhibitors; gamma-Aminobutyric Acid; Humans; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Selegiline

2019
Blocking Astrocytic GABA Restores Synaptic Plasticity in Prefrontal Cortex of Rat Model of Depression.
    Cells, 2020, 07-16, Volume: 9, Issue:7

    Topics: Animals; Astrocytes; Atrophy; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Neuronal Plasticity; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, GABA; Selegiline

2020
Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis.
    Experimental & molecular medicine, 2021, Volume: 53, Issue:7

    Topics: Animals; Clorgyline; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Male; Mice, Inbred C57BL; Molecular Imaging; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Patch-Clamp Techniques; Rats, Sprague-Dawley; Selegiline

2021