selegiline has been researched along with cocaine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.34) | 18.7374 |
| 1990's | 13 (44.83) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Finberg, JP; Tal, A | 1 |
| Caramona, MM; Osswald, W | 1 |
| Colpaert, FC; Janssen, PA; Niemegeers, CJ | 1 |
| Bigelow, GE; Garner, JE; Ginn, DH; Haberny, KA; Setoda, D; Walsh, SL; Wilkins, JN | 1 |
| Halldin, C; Lehikoinen, P; Müller, L; Någren, K; Swahn, CG | 1 |
| Møller, J; Nedergaard, OA | 1 |
| Goldberg, SR; Schindler, CW; Thorndike, EB; Yasar, S | 1 |
| Gatley, SJ | 1 |
| Alexoff, DL; Fowler, JS; Gatley, SJ; King, P; Schlyer, DJ; Shea, C; Wolf, AP | 1 |
| Goldberg, JP; Goldberg, SR; Yasar, S | 1 |
| Bernardi, G; Bonci, A; Mercuri, NB; Scarponi, M; Siniscalchi, A | 1 |
| Demuth, M; Götz, ME; Koutsilieri, E; Riederer, P; Sauer, U; Sopper, S; ter Meulen, V | 1 |
| Bartzokis, G; Beckson, M; Bridge, TP; Foster, JA; Ling, W; Mandelkern, M; Mintz, J; Newton, T | 1 |
| Castronuovo, J; Feigin, A; Innis, RB; Marek, KL; Seibyl, JP; Sheff, K; Zoghbi, S | 1 |
| Dewey, S; Ding, YS; Fischman, MW; Foltin, R; Fowler, JS; Hitzemann, R; Volkow, ND; Wang, GJ | 1 |
| Chen, A; Cumming, P; Dagher, A; Deep, P; Gjedde, A; Kapczinski, F; Reutens, D; Wong, DF; Yokoi, F | 1 |
| Azmoodeh, M; Dewey, SL; Fowler, JS; Gerasimov, M; Schiffer, WK; Volkow, ND | 1 |
| Bigelow, GE; Chiang, N; Elkashef, A; Houtsmuller, EJ; Newton, T; Notes, LD; van Sluis, N | 1 |
| Bergman, J; Gaal, J; Justinova, Z; Yasar, S | 1 |
| Belluzzi, JD; Franke, RM; Leslie, FM | 1 |
| Botrè, F; Colamonici, C; Strano-Rossi, S | 1 |
| Everhart, T; Harris, DS; Jacob, P; Jones, RT; Lin, E; Mendelson, JE | 1 |
| Alexoff, DL; Apelskog-Torres, K; Carter, P; Fahn, S; Fowler, JS; Gilmor, M; Hubbard, B; Jayne, M; King, P; Logan, J; McCall-Perez, F; Muench, L; Shea, C; Shumay, E; Telang, F; Volkow, ND; Wang, GJ; Xu, Y | 1 |
2 review(s) available for selegiline and cocaine
| Article | Year |
|---|---|
Are metabolites of l-deprenyl (selegiline) useful or harmful? Indications from preclinical research.
Topics: Amphetamine; Animals; Biotransformation; Cocaine; Cognition; Conditioning, Operant; Drug Evaluation, Preclinical; Electroencephalography; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Nootropic Agents; Phenethylamines; Rats; Rats, Inbred F344; Reinforcement, Psychology; Saimiri; Selegiline; Self Administration | 1996 |
Positron emission tomography studies of dopamine-enhancing drugs.
Topics: Animals; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Selegiline; Tomography, Emission-Computed | 1999 |
5 trial(s) available for selegiline and cocaine
| Article | Year |
|---|---|
Absence of acute cocaine interactions with the MAO-B inhibitor selegiline.
Topics: Administration, Oral; Adult; Arousal; Blood Pressure; Cocaine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Euphoria; Heart Rate; Humans; Infusions, Intravenous; Male; Monoamine Oxidase Inhibitors; Reflex, Pupillary; Selegiline; Substance Withdrawal Syndrome; Substance-Related Disorders | 1995 |
Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT.
Topics: Aged; Antiparkinson Agents; Biological Transport; Carbidopa; Cocaine; Corpus Striatum; Dopamine; Drug Therapy, Combination; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Monoamine Oxidase; Occipital Lobe; Parkinson Disease; Selegiline; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 1999 |
Transdermal selegiline and intravenous cocaine: safety and interactions.
Topics: Administration, Cutaneous; Adult; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Drug Interactions; Female; Growth Hormone; Humans; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Prolactin; Selegiline; Single-Blind Method | 2004 |
A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.
Topics: Administration, Cutaneous; Adult; Affect; Amphetamine; Amphetamines; Analysis of Variance; Cocaine; Dopamine Uptake Inhibitors; Drug Interactions; Female; Homovanillic Acid; Humans; Infusions, Intravenous; Male; Methamphetamine; Methoxyhydroxyphenylglycol; Monitoring, Physiologic; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Prolactin; Selegiline; Statistics, Nonparametric; Substance Withdrawal Syndrome; Young Adult | 2009 |
Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Brain; Carbon Radioisotopes; Clorgyline; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Functional Neuroimaging; Humans; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Positron-Emission Tomography; Selegiline; Young Adult | 2015 |
22 other study(ies) available for selegiline and cocaine
| Article | Year |
|---|---|
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Reduced peripheral presynaptic adrenoceptor sensitivity following chronic antidepressant treatment in rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clorgyline; Cocaine; Desipramine; Electric Stimulation; In Vitro Techniques; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Neurotransmitter; Selegiline; Tranylcypromine; Vas Deferens | 1985 |
Effects of clorgyline and (-)deprenyl on the deamination of normetanephrine and noradrenaline in strips and homogenates of the canine saphenous vein.
Topics: Animals; Clorgyline; Cocaine; Deamination; Dogs; Hydrocortisone; In Vitro Techniques; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Phenethylamines; Propylamines; Saphenous Vein; Selegiline | 1985 |
Evidence that a preferred substrate for type B monoamine oxidase mediates stimulus properties of MAO inhibitors: a possible role for beta-phenylethylamine in the cocaine cue.
Topics: Animals; Cocaine; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Hydrazines; Male; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Rats; Selegiline; Tranylcypromine; Tryptamines | 1980 |
Improved synthesis of some commonly used PET radioligands by the use of [11C]methyl triflate.
Topics: Benzazepines; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine; Dopamine Antagonists; Ephedrine; Hydrocarbons, Iodinated; Indicators and Reagents; Isotope Labeling; Magnetic Resonance Spectroscopy; Mesylates; Radioligand Assay; Selegiline; Tomography, Emission-Computed | 1995 |
Inhibition by (-)-deprenyl of agonist-evoked contractions in rabbit aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clorgyline; Cocaine; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Histamine H1 Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pargyline; Phenylephrine; Potassium; Rabbits; Selegiline; Serotonin Antagonists | 1994 |
Evaluation of deprenyl for cocaine-like discriminative stimulus effects in rats.
Topics: Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Electroshock; Food; Male; Rats; Rats, Inbred F344; Selegiline; Stereoisomerism | 1994 |
Estimation of upper limits on human radiation absorbed doses from carbon-11-labeled compounds.
Topics: Animals; Benztropine; Carbon Radioisotopes; Cocaine; Deoxyglucose; Dogs; Humans; Mice; Models, Biological; Papio; Putrescine; Radiation Dosage; Selegiline; Spiperone; Tissue Distribution | 1993 |
Plasma input function determination for PET using a commercial laboratory robot.
Topics: Animals; Benztropine; Blood Chemical Analysis; Carbon Radioisotopes; Cocaine; Fluorobenzenes; Humans; Methylphenidate; Papio; Phenols; Radioisotopes; Reproducibility of Results; Robotics; Selegiline; Tomography, Emission-Computed | 1995 |
Monoamine oxidase inhibition causes a long-term prolongation of the dopamine-induced responses in rat midbrain dopaminergic cells.
Topics: Amphetamine; Animals; Clorgyline; Cocaine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Isoenzymes; Membrane Potentials; Mesencephalon; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Nomifensine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Selegiline; Sulpiride | 1997 |
Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.
Topics: AIDS Dementia Complex; Carrier Proteins; Cell Survival; Cells, Cultured; Cocaine; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glutathione; HIV-1; Humans; Macrophages; Membrane Glycoproteins; Membrane Transport Proteins; Morphine; Narcotics; Nerve Tissue Proteins; Oxidative Stress; Selegiline; Substance-Related Disorders; Tumor Cells, Cultured; Up-Regulation | 1997 |
Selegiline effects on cocaine-induced changes in medial temporal lobe metabolism and subjective ratings of euphoria.
Topics: Adult; Amygdala; Brain; Cocaine; Cocaine-Related Disorders; Euphoria; Female; Glucose; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Monoamine Oxidase Inhibitors; Selegiline; Temporal Lobe; Thalamus; Tomography, Emission-Computed | 1999 |
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
Topics: Benzazepines; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine; Dihydroxyphenylalanine; Dopamine Antagonists; Drug Interactions; Fluorine Radioisotopes; Humans; Nicotine; Raclopride; Radiopharmaceuticals; Selegiline; Tomography, Emission-Computed | 1999 |
Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Synergism; Male; Microdialysis; Neuroprotective Agents; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selegiline; Time Factors | 2003 |
Discriminative stimulus and reinforcing effects of p-fluoro-L-deprenyl in monkeys.
Topics: Amphetamine-Related Disorders; Amphetamines; Animals; Association Learning; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Injections, Intramuscular; Injections, Intravenous; Methamphetamine; Motivation; Reinforcement Schedule; Saimiri; Selegiline; Self Administration; Structure-Activity Relationship | 2005 |
Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Clorgyline; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Factor Analysis, Statistical; Female; Infusion Pumps, Implantable; Injections, Intraperitoneal; Monoamine Oxidase Inhibitors; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selegiline; Sensory Thresholds; Time Factors; Vasoconstrictor Agents | 2007 |
Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for "in competition" anti-doping analysis.
Topics: Adult; Aminobutyrates; Benzhydryl Compounds; Calibration; Central Nervous System Stimulants; Cocaine; Crotonates; Doping in Sports; Ephedrine; Female; Gas Chromatography-Mass Spectrometry; Humans; Modafinil; Saliva; Selegiline; Substance Abuse Detection; Time Factors | 2008 |