selegiline has been researched along with benzofurans in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (76.47) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Buckholtz, NS; Sparks, DL | 1 |
| Olpe, HR; Schellenberg, A | 1 |
| Knoll, B; Knoll, J; Miklya, I; Moto, T; Ohde, H; Sakae, M; Yoneda, F | 1 |
| Knoll, J | 1 |
| Knoll, B; Knoll, J; Miklya, I; Shimazu, S; Yasusa, T; Yoneda, F | 1 |
| Knoll, B; Knoll, J; Miklya, I | 2 |
| Hayashi, K; Knoll, J; Sato, N; Shimazu, S; Tanigawa, A; Yoneda, F | 1 |
| Hudson, AL; Nutt, DJ; Paterson, LM; Tyacke, RJ | 1 |
| Miklya, I; Shimazu, S | 1 |
| Gaszner, P; Miklya, I | 3 |
| Bori, Z; Denes, L; Gál, A; Nagy, Z; Szilágyi, G | 1 |
| Cano, E; Fraiz, N; Orallo, F; Yáñez, M | 1 |
| Baghy, K; Eckhardt, S; Ferdinandy, P; Garami, M; Harsing, LG; Hauser, P; Knoll, J; Mervai, Z; Miklya, I; Pocza, T; Schaff, Z; Schuler, D | 1 |
| Baghy, K; Knoll, J; Mervai, Z; Miklya, I; Timar, J; Zelena, D | 1 |
5 review(s) available for selegiline and benzofurans
| Article | Year |
|---|---|
Antiaging compounds: (-)deprenyl (selegeline) and (-)1-(benzofuran-2-yl)-2-propylaminopentane, [(-)BPAP], a selective highly potent enhancer of the impulse propagation mediated release of catecholamine and serotonin in the brain.
Topics: Aging; Alzheimer Disease; Animals; Benzofurans; Brain; Catecholamines; Depression; Humans; Neuroprotective Agents; Parkinson Disease; Propylamines; Selegiline; Serotonin | 2001 |
Pharmacological studies with endogenous enhancer substances: beta-phenylethylamine, tryptamine, and their synthetic derivatives.
Topics: Animals; Antidepressive Agents; Benzofurans; Humans; Mesencephalon; Nervous System Diseases; Neuroprotective Agents; Phenethylamines; Psychotropic Drugs; Selegiline; Tryptamines | 2004 |
Treatment possibilities of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Antiparkinson Agents; Benzofurans; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Genetic Predisposition to Disease; Humans; Mesencephalon; Neuroprotective Agents; Parkinson Disease; Reproducibility of Results; Research Design; Selegiline; United States | 2004 |
The use of the synthetic enhancer substances (-)-deprenyl and (-)-BPAP in major depression.
Topics: Benzofurans; Catecholamines; Depressive Disorder, Major; Humans; Mesencephalon; Neuroprotective Agents; Selegiline; Serotonin Agents; Tryptamines | 2004 |
Major depression and the synthetic enhancer substances, (-)-deprenyl and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane.
Topics: Animals; Benzofurans; Depressive Disorder, Major; Humans; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Selegiline; Tryptamines | 2006 |
12 other study(ies) available for selegiline and benzofurans
| Article | Year |
|---|---|
Effects of 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THbetaC) on audiogenic seizures in DBA/2J mice.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Benzofurans; Carbolines; Citalopram; Clomipramine; Clorgyline; Fluoxetine; Harmine; Indoles; Methoxydimethyltryptamines; Mice; Mice, Inbred DBA; N,N-Dimethyltryptamine; Pargyline; Propylamines; Quipazine; Seizures; Selegiline | 1980 |
The sensitivity of cortical neurons to serotonin: effect of chronic treatment with antidepressants, serotonin-uptake inhibitors and monoamine-oxidase-blocking drugs.
Topics: Animals; Benzofurans; Cerebral Cortex; Clomipramine; Clorgyline; Desipramine; Electric Conductivity; gamma-Aminobutyric Acid; Male; Monoamine Oxidase Inhibitors; Neurons; Piperidines; Rats; Selegiline; Serotonin; Serotonin Antagonists | 1981 |
Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2-propylaminopentane, ((-)BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain.
Topics: Amphetamines; Amyloid; Animals; Avoidance Learning; Benzofurans; Brain; Brain Stem; Catecholamines; Cells, Cultured; Electric Stimulation; Hippocampus; Monoamine Oxidase; Neurons; Phenethylamines; Rats; Selegiline; Serotonin; Structure-Activity Relationship; Tryptamines; Tyramine | 2001 |
1-(Benzofuran-2-yl)-2-(3,3,3-trifluoropropyl)aminopentane HCl, 3-F-BPAP, antagonizes the enhancer effect of (-)-BPAP in the shuttle box and leaves the effect of (-)-deprenyl unchanged.
Topics: Adrenergic Uptake Inhibitors; Animals; Antiparkinson Agents; Avoidance Learning; Benzofurans; Brain; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Injections, Subcutaneous; Norepinephrine; Rats; Selegiline; Serotonin; Tetrabenazine | 2002 |
A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (selegiline), alpha-tocopherol was ineffective in the DATATOP study.
Topics: alpha-Tocopherol; Animals; Benzofurans; Brain; Dopamine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Parkinson Disease; Rats; Rats, Wistar; Selegiline; Treatment Failure | 2003 |
Enhancer substances: selegiline and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes.
Topics: Animals; Apomorphine; Astrocytes; Benzofurans; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dose-Response Relationship, Drug; Glial Cell Line-Derived Neurotrophic Factor; Mice; Mice, Inbred ICR; Nerve Growth Factors; Neuroprotective Agents; Selegiline | 2003 |
An HPLC tracing of the enhancer regulation in selected discrete brain areas of food-deprived rats.
Topics: Amphetamine; Animals; Benzofurans; Brain Chemistry; Catecholamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Drive; Feeding Behavior; Food Deprivation; Hunger; Male; Monoamine Oxidase Inhibitors; Motor Activity; Neurons; Neurotransmitter Agents; Orientation; Propylamines; Rats; Rats, Wistar; Selegiline; Serotonin | 2003 |
Relationship between imidazoline(2) sites and monoamine oxidase.
Topics: Animals; Benzofurans; Brain; Cell Membrane; Clorgyline; Imidazoles; Imidazoline Receptors; Ligands; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Radioligand Assay; Rats; Receptors, Drug; Selegiline | 2003 |
Cytoprotective effect of two synthetic enhancer substances, (-)-BPAP and (-)-deprenyl, on human brain capillary endothelial cells and rat PC12 cells.
Topics: Animals; Benzofurans; Brain; Capillaries; Cells, Cultured; Cytoprotection; Endothelial Cells; Humans; Hypoxia; Neuroprotective Agents; Oxidation-Reduction; PC12 Cells; Rats; Selegiline | 2006 |
(-)-Trans-epsilon-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity.
Topics: Animals; Benzofurans; Blood Platelets; Brain; Cell Line; Citalopram; Clorgyline; Dose-Response Relationship, Drug; Fluoxetine; Humans; Imipramine; Iproniazid; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Selegiline; Serotonin; Stilbenes; Synaptosomes; Tritium; Wine | 2006 |
A longevity study with enhancer substances (selegiline, BPAP) detected an unknown tumor-manifestation-suppressing regulation in rat brain.
Topics: Animals; Antineoplastic Agents; Benzofurans; Brain; Cell Line, Tumor; Dose-Response Relationship, Drug; Fibrosarcoma; Humans; Longevity; Male; Medulloblastoma; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline | 2017 |
Synthetic enhancer compounds, besides acting on biogenic amine system, influence the glutamate transmission and stress response.
Topics: Animals; Anxiety; Behavior, Animal; Benzofurans; Corticosterone; Disease Models, Animal; Drug Synergism; Glutamic Acid; Male; Maze Learning; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Selegiline; Stress, Psychological | 2020 |