selamectin has been researched along with fluphenacur* in 2 studies
1 review(s) available for selamectin and fluphenacur
Article | Year |
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Toxicology of newer pesticides for use in dogs and cats.
The past 10 years have witnessed the development of several new insecticides that have been specifically designed to exploit physiologic differences between insects and mammals. This has resulted in products that seem to have a wide margin of safety when used in dogs and cats. Compared with the more acutely toxic organophosphorous, carbamate, and heavy metal insecticides as well as with the environmental problems of bioaccumulation associated with some of the organochlorine insecticides, these newer insecticides such as fipronil, imidacloprid, selamectin, lufenuron, and nitenpyram seem to alleviate these known problems while still providing satisfactory insecticidal activity. Topics: Animals; Benzamides; Cat Diseases; Cats; Dog Diseases; Dogs; Drug-Related Side Effects and Adverse Reactions; Imidazoles; Insecticides; Ivermectin; Neonicotinoids; Nitro Compounds; Pesticides; Pyrazoles | 2002 |
1 trial(s) available for selamectin and fluphenacur
Article | Year |
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Evaluation of the comparative efficacy of selamectin against flea (Ctenocephalides felis felis) infestations on dogs and cats in simulated home environments.
The comparative efficacy of monthly administration of selamectin or lufenuron against Ctenocephalides felis felis on dogs and cats was evaluated over a 5-month period in flea-infested environments. Twenty-four dogs and 32 cats were randomly allocated to receiving a topical treatment with selamectin or an oral administration of tablets containing lufenuron/milbemycin oxime (for dogs) or lufenuron only (for cats). Each product was administered in accordance with the manufacturer's label recommendations. Eight dogs and four cats served as untreated sentinels. Treatments were administered on days 0, 30, 60, 90, and 120. Each animal received an application of 100 fleas on days -28 and -21, and then weekly applications of 20 fleas from days 91 through 147. Flea comb counts were performed on day -6, and every 2 weeks after day 0. From day 29 (dogs) or day 44 (cats) to day 150, geometric mean flea counts for selamectin were < or =0.4. Mean flea counts for animals assigned to treatment with selamectin were significantly lower (P=0.0001) than for animals assigned to treatment with lufenuron at all assessments after day 0. Topics: Animals; Antiparasitic Agents; Benzamides; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Administration Schedule; Ectoparasitic Infestations; Female; Housing, Animal; Insecticides; Ivermectin; Male; Siphonaptera; Treatment Outcome | 2002 |