secoisolariciresinol has been researched along with lignans in 126 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.79) | 18.7374 |
| 1990's | 10 (7.94) | 18.2507 |
| 2000's | 45 (35.71) | 29.6817 |
| 2010's | 58 (46.03) | 24.3611 |
| 2020's | 12 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Davin, LB; Lewis, NG; Umezawa, T | 2 |
| Adlercreutz, H; Bannwart, C; Brunow, G; Hase, T; Wähälä, K | 1 |
| Betz, JM; Casey, RE; Musser, SM; Obermeyer, WR; Page, SW; Pohland, AE | 1 |
| Fong, HH; Luyengi, L; Orcheson, LJ; Rickard, SE; Seidl, MM; Thompson, LU | 1 |
| Fong, HH; Orcheson, LJ; Rickard, SE; Seidl, MM; Thompson, LU | 1 |
| Adlercreutz, H; Hase, T; Mazur, WM; Rasku, S; Salakka, A; Wähälä, K | 1 |
| Orcheson, LJ; Rickard, SE; Seidl, MM; Thompson, LU | 1 |
| Jacobs, E; Kulling, SE; Metzler, M; Pfeiffer, E | 1 |
| Chen, J; Thompson, LU; Tou, JC | 1 |
| Thompson, LU; Tou, JC | 1 |
| Muir, AD; Westcott, ND | 1 |
| Bingham, SA; Grimwood, R; Liggins, J | 1 |
| Costa, MA; Davin, LB; Lewis, NG; Pelissier, HC; Xia, ZQ | 1 |
| Honig, DM; Metzler, M; Niemeyer, HB; Sicilia, T | 1 |
| Adlercreutz, H; Kilkkinen, A; Pietinen, P; Stumpf, K; Valsta, LM; Virtamo, J | 1 |
| Honig, DM; Kulling, SE; Metzler, M; Niemeyer, HB | 1 |
| Aman, P; Andersson, R; Eliasson, C; Kamal-Eldin, A | 1 |
| Gellerstedt, G; Henriksson, G; Zhang, L | 1 |
| Chen, J; Tan, KP; Thompson, LU; Ward, WE | 1 |
| Banskota, AH; Kadota, S; Kurashige, Y; Le Tran, Q; Nguyen, NT; Nobukawa, T; Sasahara, M; Tezuka, Y | 1 |
| Arts, IC; Hollman, PC; Lasaroms, JJ; Milder, IE; Venema, DP; Wähälä, K | 1 |
| Otto, A; Simoneit, BR; Yamamoto, S | 1 |
| Prasad, K | 1 |
| Arts, IC; Bueno de Mesquita, HB; Feskens, EJ; Hollman, PC; Kromhout, D; Milder, IE | 1 |
| Arts, IC; Hollman, PC; Milder, IE; van de Putte, B; Venema, DP | 1 |
| Eklund, PC; Mutanen, M; Oikarinen, SI; Pajari, AM; Sjöholm, RE; Smeds, AI | 1 |
| Li, TZ; Liu, RH; Su, J; Yang, BH; Zhang, C; Zhang, WD; Zhou, Y | 1 |
| Heinonen, J; Julkunen-Tiitto, R; Laitinen, J; Rousi, M; Tahvanainen, J | 1 |
| Addi, M; Baltora-Rosset, S; Bensaddek, L; Chabbert, B; Crônier, D; Doussot, J; Hano, C; Hawkins, S; Lainé, E; Lamblin, F; Maury, S; Mesnard, F | 1 |
| Banskota, AH; Kadota, S; Nguyen, NT; Nobukawa, T; Tezuka, Y | 1 |
| Blaut, M; Clavel, T; Doré, J; Engst, W; Henderson, G | 1 |
| Liu, Z; Saarinen, NM; Thompson, LU | 1 |
| Schwartz, H; Sontag, G | 1 |
| Arroo, RR; Fliniaux, O; Gutierrez, L; Hano, C; Lainé, E; Lamblin, F; Legrand, B; Martin, I; Mesnard, F | 1 |
| Arts, IC; Bueno-de-Mesquita, HB; Feskens, EJ; Hollman, PC; Kromhout, D; Milder, IE | 1 |
| Adlercreutz, H; Kallio, H; Linko, AM; Yang, B | 1 |
| Hirai, K; Kadota, S; Kobayashi, N; Koyama, J; Morita, I; Nobukawa, T; Simamura, E | 1 |
| Hosseinian, FS; Krol, ES; Muir, AD; Westcott, ND | 1 |
| Hu, C; Kitts, DD; Yuan, YV | 1 |
| Benedettelli, S; Bosi, S; Carrasco-Pancorbo, A; Cortacero-Ramírez, S; Dinelli, G; Fernández-Gutiérrez, A; Ghiselli, L; Marotti, I; Segura-Carretero, A | 1 |
| Ayella, AK; Trick, HN; Wang, W | 1 |
| Akiyama, K; Kishida, T; Kondo, A; Maruyama, M; Nakashima, Y; Ohno, F; Sugahara, T; Tominaga, S; Yamauchi, S | 1 |
| Alfermann, AW; Bayindir, U; Fuss, E | 1 |
| Eeckhaut, E; Keukeleire, DD; Possemiers, S; Struijs, K; Verstraete, W; Vincken, JP | 1 |
| Airio, M; Dings, RP; Mäkelä, S; Saarinen, NM; Smeds, AI; Wärri, A | 1 |
| Akiyama, J; Akiyama, K; Kawaguchi, Y; Kishida, T; Maruyama, M; Masuda, T; Ohuchi, M; Someya, T; Sugahara, T; Tominaga, S; Yamauchi, S; Yamawaki, M | 1 |
| Hall, C; Kubátová, A; Popova, IE | 1 |
| Kong, WX; Wang, LL; Yuan, Z | 1 |
| Akiyama, K; Kishida, T; Maruyama, M; Nakashima, Y; Nishimoto, S; Sugahara, T; Tominaga, S; Yamauchi, S; Yamawaki, M | 1 |
| Alcorn, J; Felmlee, MA; Krol, ES; Muir, AD; Simko, E; Woo, G | 1 |
| Gruppen, H; Struijs, K; Vincken, JP | 1 |
| Ardigò, D; Brighenti, F; Del Rio, D; Franzini, L; Pellegrini, N; Piatti, PM; Scazzina, F; Valtueña, S; Zavaroni, I | 1 |
| Cardellina, JH; Chang, CJ; Klausmeyer, P; McCloud, TG; Melillo, G; Scudiero, DA; Shoemaker, RH; Uranchimeg, B; Zhou, Q | 1 |
| Caton, JS; Lardy, GP; Lemley, CO; O'Neil, MR; Reynolds, LP; Vonnahme, KA; Wilson, ME | 1 |
| Kishida, T; Nishimoto, S; Shinomiya, Y; Sugahara, T; Yamamoto, T; Yamauchi, S; Yamawaki, M | 1 |
| Blaut, M; Clavel, T; Loh, G; Woting, A | 1 |
| Saarinen, NM; Thompson, LU | 1 |
| Cai, SQ; Guo, ZR; Ku, BS; Liu, GR; Liu, SL; Ma, M; Ma, XQ; Tang, J; Wang, CZ; Yang, DH; Zhang, YN; Zhao, GX | 1 |
| Hattori, M; Jin, JS | 1 |
| Fabian, CJ; Hughes, JR; Johnson, KA; Khan, QJ; Kimler, BF; Klemp, JR; Metheny, T; Petroff, BK; Phillips, TA; Setchell, KD; Sharma, P; Yeh, HW; Zalles, CM; Zhao, X | 1 |
| Briese, V; Gerber, B; Richter, DU; Theil, C | 1 |
| Attoumbré, J; Baltora-Rosset, S; Bienaimé, C; Chabbert, B; Dubois, F; Fliniaux, MA | 1 |
| Anisimova, NY; Fetisova, LV; Kiselevskii, MV; Men'shov, VM; Nifant'ev, NE; Scherbakov, AM; Shcherbakov, AE; Trishin, AV; Tsvetkov, DE; Yashunskii, DV; Zhukova, OS | 1 |
| Amaretti, A; Leonardi, A; Raimondi, S; Roncaglia, L; Rossi, M | 1 |
| Ganss, B; Sacco, SM; Thompson, LU; Ward, WE | 1 |
| Corbin, C; Gutierrez, L; Hano, C; Lainé, E; Lamblin, F; Lopez, T; Montguillon, J; Renouard, S | 1 |
| Akamatsu, M; Hasebe, A; Kawaguchi, Y; Nishiwaki, H; Shuto, Y; Yamauchi, S | 1 |
| Akiyama, K; Nishi, K; Nishimoto, S; Sugahara, T; Tominaga, S; Yamauchi, S | 1 |
| Abarzua, S; Briese, V; Piechulla, B; Richter, DU; Serikawa, T; Szewczyk, M | 1 |
| Cai, SQ; Ku, BS; Liu, SL; Ma, XQ; Wang, CZ; Wang, YF; Xu, ZK; Yang, DH; Yao, HY | 1 |
| Gan, M; Lin, S; Liu, B; Liu, M; Shi, J; Wang, S; Wu, X; Yu, Y; Yue, Z; Zhao, F; Zhu, C | 1 |
| Cai, SQ; Ku, BS; Li, MX; Liu, GR; Liu, SL; Ma, XQ; Wang, CZ; Yang, DH; Zhu, HY | 1 |
| Debouche, C; During, A; Larondelle, Y; Raas, T | 1 |
| Chen, L; Li, J; Ma, X; Pan, J; Ruan, L; Shao, T; Sun, J; Wang, R; Xu, Y; Zhang, C; Zhang, L; Zhao, X | 1 |
| Corbin, C; Hano, C; Lainé, E; Lamblin, F; Lopez, T; Renouard, S | 1 |
| Adlercreutz, H; Ignace, G; Joffe, R; Krams, I; Lejnieks, A; Lietuvietis, V; Meija, L; Samaletdin, A; Siksna, I; Söderholm, P | 1 |
| Barakzoy, E; Corbin, C; Doussot, J; Hano, C; Lainé, E; Lamblin, F; Molinié, R; Renouard, S | 1 |
| Carmichael, SL; Cogswell, ME; Correa, A; Gonzalez-Feliciano, A; Ma, C; Olney, RS; Shaw, GM | 1 |
| Chen, D; Chen, M; Fu, G; Hang, B; Lu, C; Sha, J; Wang, H; Wang, S; Wang, X; Xia, Y; Zhou, X; Zhou, Z; Zhu, P | 1 |
| Cai, SQ; Liu, SL; Tao, YL; Wang, YS; Wang, ZQ; Yang, DH; Zhang, Y; Zhang, YT | 1 |
| Holmbom, B; Moutsatsou, P; Papavassiliou, AG; Spilioti, E | 1 |
| Alcorn, J; Krol, ES; Michel, D; Muir, AD; Mukker, JK | 1 |
| Brown, NM; Heubi, JE; Jha, P; Setchell, KD; Wolfe, B; Zimmer-Nechemias, L | 1 |
| Chen, M; Du, G; Hang, B; Hu, W; Lu, C; Qin, Y; Wang, X; Wu, W; Xia, Y; Zhou, Z | 1 |
| Buśko, M; Kulik, T; Okorski, A; Perkowski, J; Pszczółkowska, A | 1 |
| Cloutier, SJ; Datla, R; Deyholos, M; Fofana, B; Ghose, K; Kirby, CW; McCallum, J; Selvaraj, K; Sweeney-Nixon, M | 1 |
| Loers, G; Nifantiev, NE; Schachner, M; Yashunsky, DV | 1 |
| Corbin, C; Demailly, H; Fliniaux, O; Gutierrez, L; Hano, C; Lainé, E; Lamblin, F; Marosevic, D; Mesnard, F; Mongelard, G; Pilard, S; Renouard, S; Tribalatc, MA | 1 |
| Bakar, F; Caglayan, MG; Nebioglu, S; Onur, F; Palabiyik, IM | 1 |
| Fofana, B; Ghose, K; McCallum, J; Sweeney-Nixon, M | 1 |
| Alcorn, J; Krol, ES; Muir, AD; Mukker, JK; Singh, RS | 1 |
| Bowen, BP; Dalisay, DS; Davin, LB; Kim, KW; Lee, C; Lewis, NG; Rübel, O; Yang, H | 1 |
| Gregersen, S; Hermansen, K; Jeppesen, PB; Mellbye, FB | 1 |
| Cui, WG; Hu, P; Hu, ZY; Lu, Q; Ma, L; Mei, QY; Xu, DY; Zhao, Q; Zhao, X; Zhou, DS; Zhou, WH | 1 |
| Álvarez, AI; Espín, JC; García-Villalba, R; González-Lobato, L; Merino, G; Miguel, V; Otero, JA; Prieto, JG | 1 |
| Aliev, OI; Anishchenko, AM; Maslov, MY; Nifantiev, NE; Plotnikov, MB; Plotnikova, TM | 1 |
| Amaretti, A; García-Villalba, R; Leonardi, A; Quartieri, A; Raimondi, S; Rossi, M; Tomàs-Barberàn, F | 1 |
| Stegeman, JJ; Tokunaga, S; Woodin, BR | 1 |
| Brecchia, G; Cartoni Mancinelli, A; Castellini, C; Dal Bosco, A; Mattioli, S; Ruggeri, S; Sebastiani, B | 1 |
| Li, JJ; Liu, SL; Yang, DH; Zhao, DD; Zhou, YJ; Zhu, S | 1 |
| Chai, X; Du, B; Feng, X; Peng, B; Su, G; Tu, P; Yang, X; Ye, Y; Zhang, R | 1 |
| Cloutier, S; Fofana, B; Ghose, K; McCallum, J; You, FM | 1 |
| Dutta, S; Khanna, A; Kharkar, PS; Sahu, NU | 1 |
| Gaya, P; Landete, JM; Medina, M; Peirotén, Á; Sánchez-Jiménez, A | 1 |
| Abdel-Rahim, EA; El-Bahr, MK; Gabr, AMM; Mabrok, HB; Smetanska, I | 1 |
| Auguin, D; Corbin, C; Cort, JR; Davin, LB; Drouet, S; Hano, C; Lainé, É; Lewis, NG; Markulin, L | 1 |
| Guo, QL; Jiang, YP; Lin, S; Liu, YF; Shi, JG; Xu, CB; Yang, YC; Zhu, CG | 1 |
| Kambouche, N; Kress, S; Said, G; Salim, B | 1 |
| Dai, X; Gao, L; Ma, G; Wu, Y; Xia, T; Xing, D | 1 |
| Auguin, D; Corbin, C; Drouet, S; Fuss, E; Gutierrez, L; Hano, C; Lainé, E; Markulin, L; Mateljak, I; Renouard, S | 1 |
| Auguin, D; Corbin, C; Decourtil, C; Drouet, S; Garros, L; Gutierrez, L; Hano, C; Lainé, E; Lopez, T; Markulin, L; Mongelard, G; Renouard, S | 1 |
| Cheng, J; Guo, Y; Huang, S; Liu, G; Liu, Y; Wei, L; Wen, Y; Yuan, G; Zou, F | 1 |
| Chen, Y; Jiang, J; Xiong, R | 1 |
| Chen, P; Cheng, C; Deng, Q; Huang, Q; McClements, DJ; Tang, H; Wang, X; Xiang, X; Yu, K; Yu, X | 1 |
| Feng, X; Liu, L; Ma, CM; Xu, HY; Zhang, G; Zhang, L; Zheng, Z; Zhuang, CC | 1 |
| Dobrowolska, K; Regulska-Ilow, B | 1 |
| Chen, J; Chen, W; Feng, J; Lv, Z; Ma, X; Qiu, S; Shao, K; Wang, L; Wu, D; Xiao, Y; Yang, Y; Zhang, L; Zhang, P; Zhou, J | 1 |
| Kilpeläinen, I; Lahtinen, MH; Mikkilä, J; Mikkonen, KS | 1 |
| Alcorn, J; Guo, Y; Mustafa, R; Purdy, SK; Reaney, MJT; Shen, J; Tse, TJ; Yang, X | 1 |
| Faleva, AV | 1 |
| Chen, C; Chen, X; Fan, Y; Feng, X; Guo, L; Huang, H; Jiang, T; Lei, Y; Li, Y; Liu, X; Lu, X; Ni, K; Peng, F; Rui, C; Wang, D; Wang, J; Wang, S; Wang, Y; Xu, N; Ye, W; Yin, Z; Zhang, H; Zhang, Y; Zhao, L | 1 |
| Capuano, E; Feskens, EJM; Fryganas, C; Hussain Zaki, UK; Trijsburg, L | 2 |
| Chiou, JC; Du, WC; Hu, J; Kong, TH; Kung, CF; Lam, CY; Li, YZ; Mok, KW; Shum, TF; Sun, ZK; Tang, HH; Wong, MS; Xiao, HH; Ye, JJ; Yu, WX; Zang, XY; Zhang, JP; Zhou, LP | 1 |
2 review(s) available for secoisolariciresinol and lignans
| Article | Year |
|---|---|
Pinoresinol-lariciresinol reductases, key to the lignan synthesis in plants.
Topics: Butylene Glycols; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Lignans; Oxidoreductases; Plant Proteins; Plants | 2019 |
The legitimacy of using dietary supplement diglycoside secoisolariciresinol (SDG) from flaxseed in cancer.
Topics: Butylene Glycols; Dietary Supplements; Flax; Humans; Lignans; Neoplasms; Seeds | 2021 |
4 trial(s) available for secoisolariciresinol and lignans
| Article | Year |
|---|---|
Intake of lignans is associated with serum enterolactone concentration in Finnish men and women.
Topics: 4-Butyrolactone; Adult; Butylene Glycols; Diet; Female; Furans; Humans; Lignans; Male; Middle Aged; Osmolar Concentration | 2003 |
Reduction in Ki-67 in benign breast tissue of high-risk women with the lignan secoisolariciresinol diglycoside.
Topics: Adult; Breast; Butylene Glycols; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Humans; Hyperplasia; Immunohistochemistry; Ki-67 Antigen; Lignans; Mammography; Middle Aged; Phytoestrogens; Pilot Projects; Premenopause; Progesterone; Risk Factors; Testosterone | 2010 |
Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans.
Topics: 4-Butyrolactone; Aged; Butylene Glycols; Dietary Supplements; Female; Flax; Glycosides; Humans; Intestinal Mucosa; Lignans; Middle Aged; Postmenopause | 2014 |
Technical note: Quantification of lignans in the urine, milk, and plasma of flaxseed cake-fed dairy sheep.
Topics: 4-Butyrolactone; Animal Feed; Animals; Butylene Glycols; Flax; Glucosides; Lignans; Milk; Seeds; Sheep | 2021 |
120 other study(ies) available for secoisolariciresinol and lignans
| Article | Year |
|---|---|
Formation of lignans (-)-secoisolariciresinol and (-)-matairesinol with Forsythia intermedia cell-free extracts.
Topics: Butylene Glycols; Cell-Free System; Chromatography, High Pressure Liquid; Furans; Lignans; Lignin; Mass Spectrometry; Plants; Stereoisomerism | 1991 |
Formation of the lignan, (-) secoisolariciresinol, by cell free extracts of Forsythia intermedia.
Topics: Butylene Glycols; Cell-Free System; Lignans; Lignin; Mass Spectrometry; Molecular Structure; Plants; Spectrophotometry, Ultraviolet; Stereoisomerism | 1990 |
Detection and identification of the plant lignans lariciresinol, isolariciresinol and secoisolariciresinol in human urine.
Topics: Adult; Butylene Glycols; Chemical Phenomena; Chemistry; Female; Furans; Gas Chromatography-Mass Spectrometry; Humans; Lignans; Lignin; Naphthols; Plant Extracts | 1989 |
Chemical studies of phytoestrogens and related compounds in dietary supplements: flax and chaparral.
Topics: Butylene Glycols; Chromatography, High Pressure Liquid; Estrogens, Non-Steroidal; Food, Fortified; Isoflavones; Lignans; Lignin; Mass Spectrometry; Phytoestrogens; Plant Preparations; Plants | 1995 |
Dose-dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed.
Topics: 4-Butyrolactone; Animals; Butylene Glycols; Colon; Dietary Fiber; Female; Glycosides; In Vitro Techniques; Lignans; Lignin; Rats; Rats, Sprague-Dawley; Regression Analysis; Seeds | 1996 |
Antitumorigenic effect of a mammalian lignan precursor from flaxseed.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylene Glycols; Carcinogens; Dietary Fiber; Female; Lignans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1996 |
Lignan and isoflavonoid concentrations in tea and coffee.
Topics: Butylene Glycols; Coffee; Flavonoids; Furans; Gas Chromatography-Mass Spectrometry; Lignans; Tea | 1998 |
Flaxseed and its mammalian lignan precursor cause a lengthening or cessation of estrous cycling in rats.
Topics: Animals; Butylene Glycols; Estrogen Antagonists; Estrus; Female; Flax; Lignans; Organ Size; Rats; Rats, Sprague-Dawley | 1998 |
Studies on the genotoxicity of the mammalian lignans enterolactone and enterodiol and their metabolic precursors at various endpoints in vitro.
Topics: 4-Butyrolactone; Aneuploidy; Animals; Bacteria; Butylene Glycols; Cattle; Cell Line; Cell-Free System; Cricetinae; Estrogens; Furans; Hypoxanthine Phosphoribosyltransferase; Intestinal Mucosa; Intestines; Lignans; Male; Micronucleus Tests; Microtubules; Mitosis; Mutagenicity Tests; Mutagens | 1998 |
Flaxseed and its lignan precursor, secoisolariciresinol diglycoside, affect pregnancy outcome and reproductive development in rats.
Topics: Anal Canal; Animals; Body Weight; Butylene Glycols; Diet; Estrus; Female; Flax; Genitalia; Lignans; Male; Milk; Organ Size; Pregnancy; Pregnancy Outcome; Prostate; Rats; Rats, Sprague-Dawley; Reproduction | 1998 |
Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures.
Topics: alpha-Linolenic Acid; Animal Feed; Animals; Anticarcinogenic Agents; Butylene Glycols; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrus; Female; Flax; Lactation; Lignans; Linseed Oil; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Organ Size; Ovary; Pregnancy; Rats; Rats, Sprague-Dawley; Sexual Maturation | 1999 |
Quantitation of the lignan secoisolariciresinol diglucoside in baked goods containing flax seed or flax meal.
Topics: Bread; Butylene Glycols; Chromatography, High Pressure Liquid; Flax; Glycosides; Lignans | 2000 |
Extraction and quantification of lignan phytoestrogens in food and human samples.
Topics: Butylene Glycols; Estrogens, Non-Steroidal; Flax; Food Analysis; Furans; Humans; Isoflavones; Lignans; Mass Spectrometry; Phytoestrogens; Plant Preparations; Reference Standards; Triticum | 2000 |
Secoisolariciresinol dehydrogenase purification, cloning, and functional expression. Implications for human health protection.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Asteraceae; Base Sequence; Butylene Glycols; Cloning, Molecular; DNA, Complementary; Escherichia coli; Gene Library; Humans; Kinetics; Lignans; Molecular Sequence Data; Molecular Weight; NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases; Plants, Medicinal; Plants, Toxic; Podophyllum; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2001 |
Identification and stereochemical characterization of lignans in flaxseed and pumpkin seeds.
Topics: Butylene Glycols; Chromatography, High Pressure Liquid; Cucurbita; Flax; Furans; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Hydrolysis; Lignans; Lignin; Seeds; Stereoisomerism | 2003 |
Flaxseed oil: healthful or harmful for men?
Topics: alpha-Linolenic Acid; Butylene Glycols; Dietary Fats; Dietary Supplements; Heart Diseases; Humans; Lignans; Linseed Oil; Male; Sex Factors | 2003 |
Studies on the metabolism of the plant lignans secoisolariciresinol and matairesinol.
Topics: Animals; Butylene Glycols; Chromatography, High Pressure Liquid; Furans; Gas Chromatography-Mass Spectrometry; Lignans; Male; Microsomes, Liver; Oxidation-Reduction; Plants; Rats; Rats, Wistar | 2003 |
High-performance liquid chromatographic analysis of secoisolariciresinol diglucoside and hydroxycinnamic acid glucosides in flaxseed by alkaline extraction.
Topics: Alkalies; Butylene Glycols; Chromatography, High Pressure Liquid; Coumaric Acids; Flax; Glycosides; Hydrolysis; Lignans; Reference Standards; Reproducibility of Results | 2003 |
The formation of beta-beta structures in lignin biosynthesis--are there two different pathways?
Topics: Butylene Glycols; Carbohydrate Conformation; Carbohydrates; Furans; Lignans; Lignin; Models, Chemical; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Wood | 2003 |
Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats.
Topics: Animal Feed; Animals; Animals, Newborn; Animals, Suckling; Butylene Glycols; Cell Differentiation; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Female; Flax; Lignans; Male; Mammary Glands, Animal; Pregnancy; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Reproduction | 2004 |
Secoisolariciresinol and isotaxiresinol inhibit tumor necrosis factor-alpha-dependent hepatic apoptosis in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Butylene Glycols; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Therapy, Combination; Furans; Galactosamine; Injections, Intraperitoneal; Interferon-gamma; Lignans; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Plants, Medicinal; Taxus; Tumor Necrosis Factor-alpha | 2004 |
Optimization of a liquid chromatography-tandem mass spectrometry method for quantification of the plant lignans secoisolariciresinol, matairesinol, lariciresinol, and pinoresinol in foods.
Topics: Butylene Glycols; Chromatography, Liquid; Food Analysis; Furans; Hydrolysis; Lignans; Mass Spectrometry; Plants; Sensitivity and Specificity | 2004 |
Lignans in resin of Araucaria angustifolia by gas chromatography/mass spectrometry.
Topics: Butylene Glycols; Furans; Gas Chromatography-Mass Spectrometry; Lignans; Lignin; Naphthols; Phenols; Pinus; Resins, Plant; Trimethylsilyl Compounds | 2004 |
Effect of chronic administration of lignan complex isolated from flaxseed on the hemopoietic system.
Topics: Analysis of Variance; Animals; Blood Platelets; Butylene Glycols; Cholesterol; Erythrocyte Indices; Erythrocytes; Female; Flax; Granulocytes; Hematocrit; Hematopoietic Stem Cells; Hemoglobins; Leukocytes; Lignans; Lipid Metabolism; Lymphocytes; Monocytes; Platelet Count; Rabbits; Time Factors | 2005 |
Intake of the plant lignans secoisolariciresinol, matairesinol, lariciresinol, and pinoresinol in Dutch men and women.
Topics: Adult; Aged; Beverages; Bread; Butylene Glycols; Diet; Female; Fruit; Furans; Humans; Lignans; Male; Middle Aged; Netherlands; Nuts; Vegetables | 2005 |
Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol.
Topics: Beverages; Butylene Glycols; Databases, Factual; Edible Grain; Food Analysis; Fruit; Furans; Humans; Lignans; Netherlands; Plants, Edible; Seeds; Vegetables | 2005 |
The plant lignans matairesinol and secoisolariciresinol administered to Min mice do not protect against intestinal tumor formation.
Topics: 4-Butyrolactone; Adenomatous Polyposis Coli Protein; Animals; Butylene Glycols; Diet; Disease Models, Animal; Female; Furans; Intestinal Neoplasms; Lignans; Male; Mice; Mice, Inbred C57BL; Plants | 2006 |
Lignans from bark of Larix olgensis var. koreana.
Topics: Antineoplastic Agents, Phytogenic; Butylene Glycols; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Furans; Inhibitory Concentration 50; Larix; Lignans; Molecular Structure; Plants, Medicinal; Stereoisomerism; Tumor Cells, Cultured | 2005 |
Ontogeny and environment as determinants of the secondary chemistry of three species of white birch.
Topics: Betula; Butylene Glycols; Environment; Fertilization; Glucosides; Lignans; Phenols; Principal Component Analysis; Species Specificity; Terpenes; Time Factors | 2005 |
Differential accumulation of monolignol-derived compounds in elicited flax (Linum usitatissimum) cell suspension cultures.
Topics: Ascomycota; Biological Factors; Botrytis; Butylene Glycols; Cell Wall; Cells, Cultured; Coumaric Acids; Flax; Fusarium; Glucosides; Lignans; Lignin; Mycelium; Phenols; Spectroscopy, Fourier Transform Infrared | 2006 |
Hypoglycemic effects of the wood of Taxus yunnanensis on streptozotocin-induced diabetic rats and its active components.
Topics: Animals; Blood Glucose; Butylene Glycols; Diabetes Mellitus, Experimental; Furans; Hypoglycemia; Lignans; Male; Molecular Structure; Plant Extracts; Rats; Rats, Wistar; Taxus; Wood | 2006 |
Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside.
Topics: 4-Butyrolactone; Bacteria, Anaerobic; Butylene Glycols; Culture Media; Glucosides; Humans; Intestines; Lignans; Phylogeny | 2006 |
Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats.
Topics: Animals; Butylene Glycols; Dioxoles; Feces; Female; Fermentation; Flax; Gas Chromatography-Mass Spectrometry; Glucosides; Humans; Lignans; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Seeds; Sesamum | 2006 |
Determination of secoisolariciresinol, lariciresinol and isolariciresinol in plant foods by high performance liquid chromatography coupled with coulometric electrode array detection.
Topics: Butylene Glycols; Calibration; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Furans; Hydrolysis; Lignans; Lignin; Molecular Structure; Naphthols; Plants, Edible; Reproducibility of Results | 2006 |
Pinoresinol-lariciresinol reductase gene expression and secoisolariciresinol diglucoside accumulation in developing flax (Linum usitatissimum) seeds.
Topics: Base Sequence; Butylene Glycols; Cloning, Molecular; DNA, Plant; Flax; Lignans; Molecular Sequence Data; Oxidoreductases; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Seeds | 2006 |
Intakes of 4 dietary lignans and cause-specific and all-cause mortality in the Zutphen Elderly Study.
Topics: Aged; Aged, 80 and over; Butylene Glycols; Cardiovascular Diseases; Cause of Death; Cohort Studies; Coronary Disease; Diet; Diet Surveys; Furans; Humans; Lignans; Male; Middle Aged; Multivariate Analysis; Neoplasms; Netherlands; Proportional Hazards Models; Prospective Studies; Wine | 2006 |
Secoisolariciresinol and matairesinol of sea buckthorn (Hippophaë rhamnoides L.) berries of different subspecies and harvesting times.
Topics: Butylene Glycols; Fruit; Furans; Gas Chromatography-Mass Spectrometry; Hippophae; Indicator Dilution Techniques; Lignans; Seeds | 2006 |
Antiallergic activity of aqueous extracts and constituents of Taxus yunnanensis.
Topics: Anti-Allergic Agents; Butylene Glycols; Calcimycin; Carbon Isotopes; Cell Line; Chromatography, High Pressure Liquid; Deuterium; Drugs, Chinese Herbal; Furans; Histamine Release; Humans; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Plant Bark; Plant Extracts; Propylene Glycols; Spectrophotometry, Infrared; Taxoids; Taxus; Wood | 2006 |
AAPH-mediated antioxidant reactions of secoisolariciresinol and SDG.
Topics: Amidines; Antioxidants; Butylene Glycols; Flax; Free Radical Scavengers; Glucosides; Lignans; Molecular Conformation; Oxidation-Reduction; Stereoisomerism; Time Factors | 2007 |
Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro.
Topics: 4-Butyrolactone; Animals; Biphenyl Compounds; Butylene Glycols; Flax; Free Radical Scavengers; Glucosides; Hydrazines; Lignans; Liposomes; Mammals; Molecular Structure; Picrates; Seeds | 2007 |
Lignan profile in seeds of modern and old Italian soft wheat (Triticum aestivum L.) cultivars as revealed by CE-MS analyses.
Topics: 4-Butyrolactone; Benzodioxoles; Butylene Glycols; Dioxoles; Electrophoresis, Capillary; Furans; Italy; Lignans; Seeds; Tandem Mass Spectrometry; Triticum | 2007 |
Enhancing lignan biosynthesis by over-expressing pinoresinol lariciresinol reductase in transgenic wheat.
Topics: Blotting, Southern; Butylene Glycols; Chromatography, High Pressure Liquid; DNA, Plant; Forsythia; Gene Expression; Lignans; Mass Spectrometry; Oxidoreductases; Plants, Genetically Modified; Polymerase Chain Reaction; Triticum | 2007 |
First stereoselective synthesis of meso-secoisolariciresinol and comparison of its biological activity with (+) and (-)-secoisolariciresinol.
Topics: Animals; Antineoplastic Agents; Butylene Glycols; Cell Line, Tumor; Cell Survival; Humans; Immunoglobulin M; Immunosuppressive Agents; Lignans; Mice; Mice, Inbred BALB C; Stereoisomerism | 2007 |
Hinokinin biosynthesis in Linum corymbulosum Reichenb.
Topics: 4-Butyrolactone; Amino Acid Sequence; Benzodioxoles; Butylene Glycols; Cells, Cultured; Cloning, Molecular; Dioxoles; DNA, Complementary; Flax; Furans; Gene Expression; Gene Library; Genes, Plant; Lignans; Molecular Sequence Data; Oxidoreductases; Phylogeny; Plant Proteins; RNA, Plant; Sequence Alignment; Sequence Homology, Amino Acid | 2008 |
Metabolism of the lignan macromolecule into enterolignans in the gastrointestinal lumen as determined in the simulator of the human intestinal microbial ecosystem.
Topics: Bacteria; Butylene Glycols; Diet; Ecosystem; Estrogens; Gastrointestinal Tract; Glucosides; Humans; Lignans; Macromolecular Substances; Models, Biological | 2008 |
Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Butylene Glycols; Carcinogens; Cell Proliferation; Dietary Supplements; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Furans; Gene Expression Regulation, Neoplastic; Humans; Lignans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Ovariectomy; Phytoestrogens; Rats; Receptors, Progesterone; Transplantation, Heterologous | 2008 |
Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid.
Topics: Butanes; Butylene Glycols; Free Radical Scavengers; Guaiacol; Lignans; Lipoxygenase Inhibitors; Oxidation-Reduction; Stereoisomerism | 2008 |
Determination of lignans in flaxseed using liquid chromatography with time-of-flight mass spectrometry.
Topics: Antioxidants; Butylene Glycols; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Flax; Gas Chromatography-Mass Spectrometry; Glucosides; Least-Squares Analysis; Lignans; Mass Spectrometry; Models, Chemical; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Microextraction; Tandem Mass Spectrometry | 2009 |
[A new 8-O-4' neolignan from Glehnia littoralis].
Topics: Apiaceae; Butylene Glycols; Caffeic Acids; Lignans; Molecular Structure; Plants, Medicinal | 2008 |
The Effect of Secoisolariciresinol on 3T3-L1 Adipocytes and the Relationship between Molecular Structure and Activity.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Butylene Glycols; Estrogens; Lignans; Lipid Metabolism; Mice; Stereoisomerism; Structure-Activity Relationship; Triglycerides | 2009 |
Effects of the flaxseed lignans secoisolariciresinol diglucoside and its aglycone on serum and hepatic lipids in hyperlipidaemic rats.
Topics: Animals; Base Sequence; Body Weight; Butylene Glycols; Dose-Response Relationship, Drug; Female; Flax; Fructose; Gene Expression; Glucosides; Hyperlipidemias; Lignans; Lipids; Liver; Male; Models, Animal; Molecular Sequence Data; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2009 |
Bacterial conversion of secoisolariciresinol and anhydrosecoisolariciresinol.
Topics: Butylene Glycols; Chromatography, High Pressure Liquid; Clostridium; Eubacterium; Fermentation; Lignans; Mass Spectrometry; Peptostreptococcus; Time Factors | 2009 |
Intake of the plant lignans matairesinol, secoisolariciresinol, pinoresinol, and lariciresinol in relation to vascular inflammation and endothelial dysfunction in middle age-elderly men and post-menopausal women living in Northern Italy.
Topics: Aged; Biomarkers; Butylene Glycols; Cardiovascular Diseases; Cross-Sectional Studies; Diet; Diet Records; Diet, Mediterranean; Endothelium, Vascular; Female; Furans; Hemodynamics; Humans; Inflammation; Italy; Lignans; Male; Middle Aged; Phytoestrogens; Surveys and Questionnaires; Vascular Diseases | 2010 |
Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii.
Topics: Antineoplastic Agents, Phytogenic; Butylene Glycols; Cardenolides; Chromones; Drug Screening Assays, Antitumor; Female; Furans; Glycosides; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lignans; Magnoliopsida; Mexico; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Structure-Activity Relationship | 2009 |
Estradiol-17beta and linseed meal interact to alter visceral organ mass and hormone concentrations from ovariectomized ewes.
Topics: Animals; Butylene Glycols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Estradiol; Female; Flax; Food-Drug Interactions; Gastric Mucosa; Insulin-Like Growth Factor I; Intestine, Small; Lignans; Liver; Organ Size; Ovariectomy; Phytoestrogens; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sheep; Stomach; Thyroxine; Triiodothyronine | 2009 |
Inhibition of the discoloration of yellowtail dark muscle by lignan.
Topics: Animals; Antioxidants; Body Weight; Butylene Glycols; Color; Female; Food Preservation; Furans; Lignans; Maillard Reaction; Meat; Mice; Mice, Inbred BALB C; Muscles; Perciformes; Solutions | 2009 |
Bacterial transformation of dietary lignans in gnotobiotic rats.
Topics: 4-Butyrolactone; Animals; Biotransformation; Butylene Glycols; Cecum; Diet; Feces; Flax; Germ-Free Life; Gram-Positive Bacteria; Lignans; Rats; Rats, Sprague-Dawley | 2010 |
Prolonged administration of secoisolariciresinol diglycoside increases lignan excretion and alters lignan tissue distribution in adult male and female rats.
Topics: Animals; Butylene Glycols; Feces; Female; Flax; Glycosides; Lignans; Male; Rats; Rats, Sprague-Dawley; Seeds; Sex Factors; Time Factors; Tissue Distribution; Urine | 2010 |
Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria.
Topics: Biotransformation; Butylene Glycols; Cluster Analysis; DNA Fingerprinting; DNA, Bacterial; DNA, Ribosomal; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Feces; Female; Flax; Gastrointestinal Tract; Humans; Lignans; Male; Molecular Sequence Data; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Young Adult | 2010 |
Human intestinal bacterium, strain END-2 is responsible for demethylation as well as lactonization during plant lignan metabolism.
Topics: 4-Butyrolactone; Bacteria, Anaerobic; Biotransformation; Butylene Glycols; Chromatography, High Pressure Liquid; Feces; Humans; Intestines; Lignans; Mass Spectrometry; Methylation; Molecular Structure; Stereoisomerism; Substrate Specificity | 2010 |
The effects of different lignans and isoflavones, tested as aglycones and glycosides, on hormone receptor-positive and -negative breast carcinoma cells in vitro.
Topics: Breast Neoplasms; Butylene Glycols; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Genistein; Humans; Immunohistochemistry; Isoflavones; L-Lactate Dehydrogenase; Lignans; Phytoestrogens; Receptors, Estrogen; Receptors, Progesterone | 2011 |
Development of antibodies against secoisolariciresinol--application to the immunolocalization of lignans in Linum usitatissimum seeds.
Topics: Animals; Antibodies; Butylene Glycols; Cattle; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Flax; Lignans; Rabbits; Seeds | 2010 |
In vitro effect of Knotolan, a new lignan from Abies sibirica, on the growth of hormone-dependent breast cancer cells.
Topics: Abies; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Estradiol; Female; Humans; Lignans; Neoplasms, Hormone-Dependent | 2010 |
Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside.
Topics: 4-Butyrolactone; Bifidobacterium; Biotransformation; Butylene Glycols; Glucosides; Lignans | 2011 |
Accessibility of ³H-secoisolariciresinol diglycoside lignan metabolites in skeletal tissue of ovariectomized rats.
Topics: Animals; Butylene Glycols; Disease Models, Animal; Female; Femur; Flax; Lignans; Lumbar Vertebrae; Osteoporosis; Ovariectomy; Phytoestrogens; Rats; Rats, Sprague-Dawley; Tibia | 2011 |
Abscisic acid regulates pinoresinol-lariciresinol reductase gene expression and secoisolariciresinol accumulation in developing flax (Linum usitatissimum L.) seeds.
Topics: Abscisic Acid; Butylene Glycols; Flax; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Lignans; Oxidoreductases; Plant Growth Regulators; Plants, Genetically Modified; Seeds | 2012 |
Larvicidal activity of (-)-dihydroguaiaretic acid derivatives against Culex pipiens.
Topics: Animals; Butylene Glycols; Culex; Disease Vectors; Guaiacol; Hydrophobic and Hydrophilic Interactions; Hydroxylation; Insect Control; Insecticides; Larva; Lethal Dose 50; Lignans; Stereoisomerism; Structure-Activity Relationship | 2011 |
(-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice.
Topics: Animals; Butylene Glycols; Diet, High-Fat; Dietary Fats; Disease Models, Animal; Gene Expression; Humans; Lignans; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR alpha; Weight Gain | 2012 |
Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20.
Topics: 4-Butyrolactone; Anticarcinogenic Agents; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogens; Female; Furans; Humans; Lignans; Phytoestrogens; Selective Estrogen Receptor Modulators; Tamoxifen | 2012 |
The antidepressant effect of secoisolariciresinol, a lignan-type phytoestrogen constituent of flaxseed, on ovariectomized mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Butylene Glycols; Depression; Female; Flax; Lignans; Mice; Ovariectomy; Phytoestrogens | 2013 |
[Chemical constituents from roots of Machilus yaoshansis].
Topics: Butylene Glycols; Catechin; Lauraceae; Lignans; Lignin; Naphthols; Plant Roots | 2012 |
Production of secoisolariciresinol from defatted flaxseed by bacterial biotransformation.
Topics: Adult; Bacteroidaceae; Biotransformation; Butylene Glycols; Chromatography, High Pressure Liquid; Feces; Female; Fermentation; Flax; Glucosides; Humans; Hydrolysis; Lignans; Male; Phylogeny; RNA, Ribosomal, 16S; Young Adult | 2012 |
Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.
Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Butylene Glycols; Caco-2 Cells; Cell Differentiation; Chemokine CCL2; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Furans; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Intestines; Lignans; NF-kappa B; Plant Extracts; Signal Transduction | 2012 |
Antidepressant-like effect of flaxseed secoisolariciresinol diglycoside in ovariectomized mice subjected to unpredictable chronic stress.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Body Weight; Brain-Derived Neurotrophic Factor; Butylene Glycols; Corticosterone; Cytokines; Female; Flax; Glycosides; Lignans; Mice; Mice, Inbred ICR; Motor Activity; Ovariectomy; Stress, Psychological | 2013 |
Identification and characterization of cis-acting elements involved in the regulation of ABA- and/or GA-mediated LuPLR1 gene expression and lignan biosynthesis in flax (Linum usitatissimum L.) cell cultures.
Topics: Abscisic Acid; Biosynthetic Pathways; Butylene Glycols; Cell Culture Techniques; Chromatography, High Pressure Liquid; Flax; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Gibberellins; Glucuronidase; Lignans; Oxidoreductases; Regulatory Sequences, Nucleic Acid; Transformation, Genetic | 2013 |
Dietary intake and major sources of plant lignans in Latvian men and women.
Topics: Adult; Aged; Bread; Butylene Glycols; Cardiovascular Diseases; Diet; Feeding Behavior; Female; Flax; Furans; Humans; Latvia; Lignans; Male; Middle Aged; Neoplasms; Phenols; Phytoestrogens; Plant Extracts; Sex Factors | 2013 |
Flaxseed (Linum usitatissimum L.) extract as well as (+)-secoisolariciresinol diglucoside and its mammalian derivatives are potent inhibitors of α-amylase activity.
Topics: alpha-Glucosidases; Animals; Butylene Glycols; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flax; Glucosides; Glycoside Hydrolase Inhibitors; Intestines; Lignans; Molecular Structure; Pancreatic alpha-Amylases; Plant Extracts; Rats; Structure-Activity Relationship; Swine | 2013 |
Hypospadias and maternal intake of phytoestrogens.
Topics: Adult; Butylene Glycols; Case-Control Studies; Diet, Vegetarian; Female; Genistein; Humans; Hypospadias; Infant, Newborn; Isoflavones; Lignans; Male; Odds Ratio; Phytoestrogens; Pregnancy; Prenatal Exposure Delayed Effects; Risk Assessment; Risk Factors; Surveys and Questionnaires | 2013 |
Urinary phytoestrogen levels related to idiopathic male infertility in Chinese men.
Topics: Adult; Butylene Glycols; China; Diet; Feeding Behavior; Genistein; Humans; Infertility, Male; Isoflavones; Lignans; Male; Phytoestrogens; Semen; Semen Analysis; Sperm Count; Tandem Mass Spectrometry | 2013 |
Cloning, expression, and characterization of the β-glucosidase hydrolyzing secoisolariciresinol diglucoside to secoisolariciresinol from Bacteroides uniformis ZL1.
Topics: Amino Acid Sequence; Bacteroides; beta-Glucosidase; Butylene Glycols; Cloning, Molecular; DNA, Bacterial; Enzyme Stability; Escherichia coli; Gene Expression; Glucosides; Hydrogen-Ion Concentration; Hydrolysis; Lignans; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Temperature | 2014 |
Lignans 7-hydroxymatairesinol and 7-hydroxymatairesinol 2 exhibit anti-inflammatory activity in human aortic endothelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aorta; Butylene Glycols; Cell Adhesion; Cells, Cultured; Endothelial Cells; Furans; Humans; Intercellular Adhesion Molecule-1; Lignans; MAP Kinase Kinase 4; Monocytes; NF-kappa B; Picea; PPAR gamma; Receptors, Estrogen; Vascular Cell Adhesion Molecule-1 | 2014 |
Permeability and conjugative metabolism of flaxseed lignans by Caco-2 human intestinal cells.
Topics: 4-Butyrolactone; Algorithms; Butylene Glycols; Caco-2 Cells; Chromatography, High Pressure Liquid; Flax; Glucosides; Humans; Intestinal Mucosa; Lignans; Molecular Structure; Permeability | 2014 |
Combined effects of urinary phytoestrogens metabolites and polymorphisms in metabolic enzyme gene on idiopathic male infertility.
Topics: Adult; Arylamine N-Acetyltransferase; Asian People; Biotransformation; Butylene Glycols; Case-Control Studies; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B6; Humans; Infertility, Male; Lignans; Male; Phytoestrogens; Polymorphism, Single Nucleotide; Young Adult | 2014 |
Plant lignans inhibit growth and trichothecene biosynthesis in Fusarium graminearum.
Topics: Antifungal Agents; Butylene Glycols; Edible Grain; Furans; Fusarium; Gene Expression; Genes, Fungal; Lignans; Microbial Sensitivity Tests; RNA, Messenger; Transcription, Genetic; Trichothecenes; Triticum | 2014 |
Identification and functional characterization of a flax UDP-glycosyltransferase glucosylating secoisolariciresinol (SECO) into secoisolariciresinol monoglucoside (SMG) and diglucoside (SDG).
Topics: Amino Acid Motifs; Amino Acid Sequence; Biosynthetic Pathways; Butylene Glycols; Chromatography, High Pressure Liquid; Cloning, Molecular; Conserved Sequence; DNA, Complementary; Enzyme Assays; Expressed Sequence Tags; Flax; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Glucosides; Glycosylation; Glycosyltransferases; Kinetics; Lignans; Mass Spectrometry; Molecular Sequence Data; Organ Specificity; Oxidoreductases; Phylogeny; Sesamum | 2014 |
Neural cell activation by phenolic compounds from the Siberian larch (Larix sibirica).
Topics: Animals; Astrocytes; Butylene Glycols; Disease Models, Animal; Female; Larix; Lignans; Lignin; Male; Mice; Mice, Inbred C57BL; Models, Neurological; Molecular Structure; Naphthols; Neurites; Phenols; Quercetin; Schwann Cells; Stereoisomerism | 2014 |
RNAi-mediated pinoresinol lariciresinol reductase gene silencing in flax (Linum usitatissimum L.) seed coat: consequences on lignans and neolignans accumulation.
Topics: Butylene Glycols; Flax; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Glucosides; Lignans; Oxidoreductases; Plant Proteins; Plants, Genetically Modified; RNA Interference; Seeds | 2014 |
Gold nanoparticle-lignan complexes inhibited MCF-7 cell proliferation in vitro: a novel conjugation for cancer therapy.
Topics: beta-Cyclodextrins; Butylene Glycols; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Furans; Gold; Humans; Ligands; Lignans; MCF-7 Cells; Metal Nanoparticles; Molecular Structure; Organogold Compounds; Structure-Activity Relationship; Tumor Cells, Cultured | 2015 |
Histidine 352 (His352) and tryptophan 355 (Trp355) are essential for flax UGT74S1 glucosylation activity toward secoisolariciresinol.
Topics: Butylene Glycols; Enzyme Activation; Flax; Gene Expression; Glycosylation; Histidine; Kinetics; Ligands; Lignans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Tryptophan | 2015 |
Comparative pharmacokinetics of purified flaxseed and associated mammalian lignans in male Wistar rats.
Topics: 4-Butyrolactone; Administration, Oral; Animals; Biological Availability; Butylene Glycols; Dietary Supplements; Dose-Response Relationship, Drug; Estrogens; Flax; Glucosides; Half-Life; Injections, Intravenous; Intestinal Absorption; Kinetics; Lignans; Male; Metabolic Clearance Rate; Phytoestrogens; Random Allocation; Rats, Wistar; Seeds | 2015 |
Dirigent Protein-Mediated Lignan and Cyanogenic Glucoside Formation in Flax Seed: Integrated Omics and MALDI Mass Spectrometry Imaging.
Topics: Butylene Glycols; Flax; Furans; Glucosides; Glycosides; Lignans; Molecular Structure; Nitriles; Seeds; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2015 |
Cafestol, a Bioactive Substance in Coffee, Stimulates Insulin Secretion and Increases Glucose Uptake in Muscle Cells: Studies in Vitro.
Topics: Alkaloids; Animals; Butylene Glycols; Caffeic Acids; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Diterpenes; Glucose; Guinea Pigs; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lignans; Muscle, Skeletal | 2015 |
Secoisolariciresinol diglycoside, a flaxseed lignan, exerts analgesic effects in a mouse model of type 1 diabetes: Engagement of antioxidant mechanism.
Topics: Analgesics; Animals; Antioxidants; Butylene Glycols; Cyclic N-Oxides; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Flax; Glycosides; Hyperalgesia; Lignans; Male; Mice; Neuralgia; Sciatic Nerve; Spinal Cord; tert-Butylhydroperoxide | 2015 |
Effect of bovine ABCG2 polymorphism Y581S SNP on secretion into milk of enterolactone, riboflavin and uric acid.
Topics: 4-Butyrolactone; Animals; ATP-Binding Cassette Transporters; Biological Transport; Butylene Glycols; Cattle; Dogs; Female; Lactation; Lignans; Madin Darby Canine Kidney Cells; Milk; Mitoxantrone; Polymorphism, Single Nucleotide; Riboflavin; Uric Acid | 2016 |
Hemorheological effects of secoisolariciresinol in ovariectomized rats.
Topics: Animals; Blood Viscosity; Butylene Glycols; Erythrocyte Aggregation; Erythrocyte Deformability; Estradiol; Female; Hematocrit; Hemorheology; Lignans; Lipid Peroxidation; Ovariectomy; Ovary; Phytoestrogens; Rats; Rats, Wistar | 2016 |
Detection of novel metabolites of flaxseed lignans in vitro and in vivo.
Topics: 4-Butyrolactone; Adult; Bifidobacterium pseudocatenulatum; Butylene Glycols; Dietary Supplements; Feces; Female; Flax; Furans; Gastrointestinal Microbiome; Glucosides; Humans; Intestinal Mucosa; Intestines; Lignans; Male; Middle Aged; Prebiotics; Probiotics; Young Adult | 2016 |
Plant lignan secoisolariciresinol suppresses pericardial edema caused by dioxin-like compounds in developing zebrafish: Implications for suppression of morphological abnormalities.
Topics: Abnormalities, Drug-Induced; Animals; Butylene Glycols; Dioxins; Edema; Embryo, Nonmammalian; Lignans; Pericardial Effusion; Phytoestrogens; Zebrafish | 2016 |
Performance and egg quality of laying hens fed flaxseed: highlights on n-3 fatty acids, cholesterol, lignans and isoflavones.
Topics: 4-Butyrolactone; alpha-Linolenic Acid; Animal Feed; Animals; Butylene Glycols; Chickens; Cholesterol; Diet; Dietary Supplements; Eggs; Fatty Acids; Fatty Acids, Omega-3; Female; Flax; Isoflavones; Lignans; Phytoestrogens; Seeds | 2017 |
Characterization of Klebsiella sp. strain S1: a bacterial producer of secoisolariciresinol through biotransformation.
Topics: Bacterial Typing Techniques; Base Composition; Biotransformation; Butylene Glycols; DNA, Bacterial; DNA, Ribosomal; Fatty Acids; Flax; Humans; Intestines; Klebsiella; Lignans; Molecular Structure; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2017 |
Alashinols F and G, two lignans from stem bark of Syringa pinnatifolia.
Topics: Anti-Inflammatory Agents; Butylene Glycols; Hypoxia; Lignans; Magnetic Resonance Spectroscopy; Medicine, Mongolian Traditional; Molecular Structure; Plant Bark; Spectrum Analysis; Syringa | 2017 |
UGT74S1 is the key player in controlling secoisolariciresinol diglucoside (SDG) formation in flax.
Topics: Butylene Glycols; Evolution, Molecular; Flax; Gene Duplication; Gene Expression; Genes, Plant; Genetic Variation; Genome, Plant; Glucosides; Lignans | 2017 |
Molecular docking prediction and in vitro studies elucidate anti-cancer activity of phytoestrogens.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Butylene Glycols; Caspase 3; Caspase 7; Cell Line, Tumor; Computer Simulation; Down-Regulation; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Lignans; MCF-7 Cells; Molecular Docking Simulation; Phytoestrogens | 2017 |
Incomplete metabolism of phytoestrogens by gut microbiota from children under the age of three.
Topics: 4-Butyrolactone; Adult; Butylene Glycols; Case-Control Studies; Child, Preschool; Coumarins; Equol; Feces; Female; Furans; Gastrointestinal Microbiome; Humans; Hydrolyzable Tannins; Infant; Isoflavones; Lignans; Male; Phytoestrogens; Polyphenols | 2018 |
Determination of lignans, phenolic acids and antioxidant capacity in transformed hairy root culture of Linum usitatissimum.
Topics: Antioxidants; Biphenyl Compounds; Butylene Glycols; Flax; Furans; Glucosides; Hydroxybenzoates; Lignans; Picrates; Plant Roots; Tissue Culture Techniques | 2018 |
A genome-wide analysis of the flax (Linum usitatissimum L.) dirigent protein family: from gene identification and evolution to differential regulation.
Topics: Amino Acid Motifs; Butylene Glycols; Cell Wall; Evolution, Molecular; Flax; Gene Expression Regulation, Plant; Lignans; Multigene Family; Phylogeny; Plant Proteins; Real-Time Polymerase Chain Reaction | 2018 |
[Lignanoids from an aqueous extract of the roots of Codonopsis pilosula].
Topics: Animals; Butylene Glycols; Codonopsis; Drugs, Chinese Herbal; Furans; Lignans; Microsomes, Liver; Molecular Structure; Plant Extracts; Plant Roots; Rats | 2016 |
Identification of Phenolic Compounds from Nettle as New Candidate Inhibitors of Main Enzymes Responsible on Type-II Diabetes.
Topics: alpha-Amylases; beta-Glucosidase; Blood Glucose; Butylene Glycols; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Drug Discovery; Humans; Hypoglycemic Agents; Insulin; Lignans; Molecular Docking Simulation; Plant Extracts; Urtica dioica | 2020 |
A variable loop involved in the substrate selectivity of pinoresinol/lariciresinol reductase from Camellia sinensis.
Topics: Butylene Glycols; Camellia sinensis; Furans; Lignans; Mutagenesis, Site-Directed; Oxidoreductases; Sequence Homology, Amino Acid; Substrate Specificity | 2019 |
The control exerted by ABA on lignan biosynthesis in flax (Linum usitatissimum L.) is modulated by a Ca
Topics: Abscisic Acid; Butylene Glycols; Calcium; Calmodulin; Chromatography, High Pressure Liquid; Flax; Gene Expression Regulation, Plant; Glucuronidase; Lignans; Plant Growth Regulators; Plant Proteins; Protein Kinase C; Real-Time Polymerase Chain Reaction; Signal Transduction; Transcriptome | 2019 |
Associations between semen phytoestrogens concentrations and semen quality in Chinese men.
Topics: Adult; Butylene Glycols; China; Cross-Sectional Studies; Genistein; Humans; Lignans; Male; Phytoestrogens; Semen; Sperm Count; Sperm Motility; Spermatozoa | 2019 |
Cytotoxic lignans from
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Butylene Glycols; Cell Death; Cell Line, Tumor; Cryptocarya; Flavonoids; Humans; Inhibitory Concentration 50; Lignans; Triterpenes | 2021 |
Effect of flaxseed polyphenols on physical stability and oxidative stability of flaxseed oil-in-water nanoemulsions.
Topics: Antioxidants; Butylene Glycols; Emulsions; Flax; Glucosides; Hydrolysis; Lignans; Linseed Oil; Nanostructures; Oxidation-Reduction; Plant Extracts; Polyphenols; Water | 2019 |
Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Topics: Arabidopsis; Arabidopsis Proteins; Butylene Glycols; Catalytic Domain; Crystallography, X-Ray; Furans; Isatis; Lignans; Models, Molecular; Mutagenesis, Site-Directed; Oxidoreductases; Phylogeny; Plant Proteins; Protein Engineering; Protein Multimerization; Static Electricity; Substrate Specificity | 2021 |
Kraft Process-Formation of Secoisolariciresinol Structures and Incorporation of Fatty Acids in Kraft Lignin.
Topics: Butylene Glycols; Fatty Acids; Lignans; Lignin | 2021 |
Oral Pharmacokinetics of Enriched Secoisolariciresinol Diglucoside and Its Polymer in Rats.
Topics: 4-Butyrolactone; Animals; Biological Availability; Butylene Glycols; Female; Flax; Glucosides; Lignans; Molecular Structure; Polymers; Rats; Rats, Wistar; Seeds | 2021 |
Comment on Kraft Process─Formation of Secoisolariciresinol Structures and Incorporation of Fatty Acids in Kraft Lignin.
Topics: Butylene Glycols; Fatty Acids; Lignans; Lignin | 2022 |
Secondary metabolite pathway of SDG (secoisolariciresinol) was observed to trigger ROS scavenging system in response to Ca
Topics: Butylene Glycols; Calcium Chloride; Gene Expression Regulation, Plant; Gossypium; Lignans; Plant Proteins; Reactive Oxygen Species; Stress, Physiological; Sustainable Development | 2022 |
Topics: Butylene Glycols; Colon; Fermentation; Flax; Gastrointestinal Tract; Lignans; Tea | 2022 |
Influence of different processing method on lignan content of selected Malaysian plant-based foods.
Topics: Butylene Glycols; Chromatography, Liquid; Fabaceae; Flax; Lignans; Tandem Mass Spectrometry; Tea | 2023 |
Identification of the Microbial Transformation Products of Secoisolariciresinol Using an Untargeted Metabolomics Approach and Evaluation of the Osteogenic Activities of the Metabolites.
Topics: 4-Butyrolactone; Butylene Glycols; Diet; Humans; Lignans | 2023 |