Page last updated: 2024-08-24

secoisolariciresinol and 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol

secoisolariciresinol has been researched along with 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's10 (55.56)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Fong, HH; Luyengi, L; Orcheson, LJ; Rickard, SE; Seidl, MM; Thompson, LU1
Jacobs, E; Kulling, SE; Metzler, M; Pfeiffer, E1
Bingham, SA; Grimwood, R; Liggins, J1
Blaut, M; Clavel, T; Doré, J; Engst, W; Henderson, G1
Hu, C; Kitts, DD; Yuan, YV1
Airio, M; Dings, RP; Mäkelä, S; Saarinen, NM; Smeds, AI; Wärri, A1
Blaut, M; Clavel, T; Loh, G; Woting, A1
Cai, SQ; Guo, ZR; Ku, BS; Liu, GR; Liu, SL; Ma, M; Ma, XQ; Tang, J; Wang, CZ; Yang, DH; Zhang, YN; Zhao, GX1
Hattori, M; Jin, JS1
Amaretti, A; Leonardi, A; Raimondi, S; Roncaglia, L; Rossi, M1
Abarzua, S; Briese, V; Piechulla, B; Richter, DU; Serikawa, T; Szewczyk, M1
Debouche, C; During, A; Larondelle, Y; Raas, T1
Alcorn, J; Krol, ES; Michel, D; Muir, AD; Mukker, JK1
Alcorn, J; Krol, ES; Muir, AD; Mukker, JK; Singh, RS1
Amaretti, A; García-Villalba, R; Leonardi, A; Quartieri, A; Raimondi, S; Rossi, M; Tomàs-Barberàn, F1
Brecchia, G; Cartoni Mancinelli, A; Castellini, C; Dal Bosco, A; Mattioli, S; Ruggeri, S; Sebastiani, B1
Feng, X; Liu, L; Ma, CM; Xu, HY; Zhang, G; Zhang, L; Zheng, Z; Zhuang, CC1
Alcorn, J; Guo, Y; Mustafa, R; Purdy, SK; Reaney, MJT; Shen, J; Tse, TJ; Yang, X1

Trials

1 trial(s) available for secoisolariciresinol and 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol

ArticleYear
Technical note: Quantification of lignans in the urine, milk, and plasma of flaxseed cake-fed dairy sheep.
    Journal of dairy science, 2021, Volume: 104, Issue:1

    Topics: 4-Butyrolactone; Animal Feed; Animals; Butylene Glycols; Flax; Glucosides; Lignans; Milk; Seeds; Sheep

2021

Other Studies

17 other study(ies) available for secoisolariciresinol and 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol

ArticleYear
Dose-dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed.
    The Journal of nutrition, 1996, Volume: 126, Issue:8

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Colon; Dietary Fiber; Female; Glycosides; In Vitro Techniques; Lignans; Lignin; Rats; Rats, Sprague-Dawley; Regression Analysis; Seeds

1996
Studies on the genotoxicity of the mammalian lignans enterolactone and enterodiol and their metabolic precursors at various endpoints in vitro.
    Mutation research, 1998, Aug-07, Volume: 416, Issue:1-2

    Topics: 4-Butyrolactone; Aneuploidy; Animals; Bacteria; Butylene Glycols; Cattle; Cell Line; Cell-Free System; Cricetinae; Estrogens; Furans; Hypoxanthine Phosphoribosyltransferase; Intestinal Mucosa; Intestines; Lignans; Male; Micronucleus Tests; Microtubules; Mitosis; Mutagenicity Tests; Mutagens

1998
Extraction and quantification of lignan phytoestrogens in food and human samples.
    Analytical biochemistry, 2000, Dec-01, Volume: 287, Issue:1

    Topics: Butylene Glycols; Estrogens, Non-Steroidal; Flax; Food Analysis; Furans; Humans; Isoflavones; Lignans; Mass Spectrometry; Phytoestrogens; Plant Preparations; Reference Standards; Triticum

2000
Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside.
    FEMS microbiology ecology, 2006, Volume: 55, Issue:3

    Topics: 4-Butyrolactone; Bacteria, Anaerobic; Butylene Glycols; Culture Media; Glucosides; Humans; Intestines; Lignans; Phylogeny

2006
Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:11

    Topics: 4-Butyrolactone; Animals; Biphenyl Compounds; Butylene Glycols; Flax; Free Radical Scavengers; Glucosides; Hydrazines; Lignans; Liposomes; Mammals; Molecular Structure; Picrates; Seeds

2007
Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.
    International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5

    Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Butylene Glycols; Carcinogens; Cell Proliferation; Dietary Supplements; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Furans; Gene Expression Regulation, Neoplastic; Humans; Lignans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Ovariectomy; Phytoestrogens; Rats; Receptors, Progesterone; Transplantation, Heterologous

2008
Bacterial transformation of dietary lignans in gnotobiotic rats.
    FEMS microbiology ecology, 2010, Volume: 72, Issue:3

    Topics: 4-Butyrolactone; Animals; Biotransformation; Butylene Glycols; Cecum; Diet; Feces; Flax; Germ-Free Life; Gram-Positive Bacteria; Lignans; Rats; Rats, Sprague-Dawley

2010
Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria.
    BMC microbiology, 2010, Apr-16, Volume: 10

    Topics: Biotransformation; Butylene Glycols; Cluster Analysis; DNA Fingerprinting; DNA, Bacterial; DNA, Ribosomal; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Feces; Female; Flax; Gastrointestinal Tract; Humans; Lignans; Male; Molecular Sequence Data; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Young Adult

2010
Human intestinal bacterium, strain END-2 is responsible for demethylation as well as lactonization during plant lignan metabolism.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:8

    Topics: 4-Butyrolactone; Bacteria, Anaerobic; Biotransformation; Butylene Glycols; Chromatography, High Pressure Liquid; Feces; Humans; Intestines; Lignans; Mass Spectrometry; Methylation; Molecular Structure; Stereoisomerism; Substrate Specificity

2010
Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside.
    Applied microbiology and biotechnology, 2011, Volume: 92, Issue:1

    Topics: 4-Butyrolactone; Bifidobacterium; Biotransformation; Butylene Glycols; Glucosides; Lignans

2011
Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:4

    Topics: 4-Butyrolactone; Anticarcinogenic Agents; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogens; Female; Furans; Humans; Lignans; Phytoestrogens; Selective Estrogen Receptor Modulators; Tamoxifen

2012
Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.
    The Journal of nutrition, 2012, Volume: 142, Issue:10

    Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Butylene Glycols; Caco-2 Cells; Cell Differentiation; Chemokine CCL2; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Furans; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Intestines; Lignans; NF-kappa B; Plant Extracts; Signal Transduction

2012
Permeability and conjugative metabolism of flaxseed lignans by Caco-2 human intestinal cells.
    Journal of natural products, 2014, Jan-24, Volume: 77, Issue:1

    Topics: 4-Butyrolactone; Algorithms; Butylene Glycols; Caco-2 Cells; Chromatography, High Pressure Liquid; Flax; Glucosides; Humans; Intestinal Mucosa; Lignans; Molecular Structure; Permeability

2014
Comparative pharmacokinetics of purified flaxseed and associated mammalian lignans in male Wistar rats.
    The British journal of nutrition, 2015, Mar-14, Volume: 113, Issue:5

    Topics: 4-Butyrolactone; Administration, Oral; Animals; Biological Availability; Butylene Glycols; Dietary Supplements; Dose-Response Relationship, Drug; Estrogens; Flax; Glucosides; Half-Life; Injections, Intravenous; Intestinal Absorption; Kinetics; Lignans; Male; Metabolic Clearance Rate; Phytoestrogens; Random Allocation; Rats, Wistar; Seeds

2015
Detection of novel metabolites of flaxseed lignans in vitro and in vivo.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:7

    Topics: 4-Butyrolactone; Adult; Bifidobacterium pseudocatenulatum; Butylene Glycols; Dietary Supplements; Feces; Female; Flax; Furans; Gastrointestinal Microbiome; Glucosides; Humans; Intestinal Mucosa; Intestines; Lignans; Male; Middle Aged; Prebiotics; Probiotics; Young Adult

2016
Performance and egg quality of laying hens fed flaxseed: highlights on n-3 fatty acids, cholesterol, lignans and isoflavones.
    Animal : an international journal of animal bioscience, 2017, Volume: 11, Issue:4

    Topics: 4-Butyrolactone; alpha-Linolenic Acid; Animal Feed; Animals; Butylene Glycols; Chickens; Cholesterol; Diet; Dietary Supplements; Eggs; Fatty Acids; Fatty Acids, Omega-3; Female; Flax; Isoflavones; Lignans; Phytoestrogens; Seeds

2017
Oral Pharmacokinetics of Enriched Secoisolariciresinol Diglucoside and Its Polymer in Rats.
    Journal of natural products, 2021, 06-25, Volume: 84, Issue:6

    Topics: 4-Butyrolactone; Animals; Biological Availability; Butylene Glycols; Female; Flax; Glucosides; Lignans; Molecular Structure; Polymers; Rats; Rats, Wistar; Seeds

2021