sdz nvi-085 has been researched along with clonidine in 5 studies
*Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. [MeSH]
*Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. [MeSH]
| Studies (sdz nvi-085) | Trials (sdz nvi-085) | Recent Studies (post-2010) (sdz nvi-085) | Studies (clonidine) | Trials (clonidine) | Recent Studies (post-2010) (clonidine) |
|---|---|---|---|---|---|
| 10 | 1 | 0 | 13,692 | 2,044 | 1,394 |
| Protein | Taxonomy | sdz nvi-085 (IC50) | clonidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.101 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0115 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.002 | |
| Nischarin | Rattus norvegicus (Norway rat) | 0.3662 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boer, R; Eltze, M | 1 |
| Büscher, R; Insel, PA; Michel, MC | 1 |
| Oriowo, MA | 1 |
| Kalkman, HO; Neumann, V | 1 |
| Hasegawa, Y; Ono, H; Wada, T | 1 |
5 other study(ies) available for sdz nvi-085 and clonidine
| Article | Year |
|---|---|
The adrenoceptor agonist, SDZ NVI 085, discriminates between alpha 1A- and alpha 1B-adrenoceptor subtypes in vas deferens, kidney and aorta of the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; In Vitro Techniques; Isradipine; Kidney; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Oxazines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vas Deferens; Vasoconstriction | 1992 |
Is SDZ NVI-085 an alpha 1-adrenoceptor subtype-selective agonist?
Topics: Adrenergic alpha-Agonists; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cattle; Cell Line; Cerebral Cortex; Clonidine; In Vitro Techniques; Inositol Phosphates; Kidney; Norepinephrine; Oxazines; Prazosin; Rats; Receptors, Adrenergic, alpha; Spleen; Transfection | 1994 |
Alpha 1-adrenoceptor subtype(s) mediating noradrenaline-induced contractions of the guinea-pig aorta.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Dioxanes; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Oxazines; Prazosin; Receptors, Adrenergic, alpha-1 | 1994 |
Evidence for a 5-HT1D receptor-mediated hypothermic effect of the alpha 1-adrenoceptor agonist, SDZ NVI-085, in guinea-pigs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Bridged-Ring Compounds; Clonidine; Guinea Pigs; In Vitro Techniques; Male; Oxadiazoles; Oxazines; Piperazines; Prazosin; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Characterization of alpha1-adrenoceptor subtypes in facilitation of rat spinal motoneuron activity.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Bridged-Ring Compounds; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Male; Methoxamine; Motor Neurons; Norepinephrine; Oxazines; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Spinal Cord | 1997 |