Page last updated: 2024-09-05

sdz ens 163 and pilocarpine

sdz ens 163 has been researched along with pilocarpine in 2 studies

Compound Research Comparison

Studies (sdz ens 163)	Trials (sdz ens 163)	Recent Studies (post-2010) (sdz ens 163)	Studies (pilocarpine)	Trials (pilocarpine)	Recent Studies (post-2010) (pilocarpine)
6	1	0	7,334	340	1,528

Protein Interaction Comparison

Protein	Taxonomy	pilocarpine (IC50)
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	3.0267
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	3.84
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	3.84
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	3.84
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	3.84

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Amstutz, R; Boelsterli, J; Bolliger, G; Floersheim, P; Gammenthaler, H; Gmelin, G; Shapiro, G; Supavilai, P; Walkinshaw, M	1
Boddeke, H; Enz, A; Rudin, M; Sauter, A; Shapiro, G	1

Other Studies

2 other study(ies) available for sdz ens 163 and pilocarpine

Article	Year
Muscarinic activity of the thiolactone, lactam, lactol, and thiolactol analogues of pilocarpine and a hypothetical model for the binding of agonists to the m1 receptor. Journal of medicinal chemistry, 1992, Volume: 35, Issue:1 Topics: Animals; Binding, Competitive; Crystallography; Guinea Pigs; Lactams; Male; Mice; Models, Biological; Parasympathomimetics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds	1992
SDZ ENS 163 a novel pilocarpine like drug: pharmacological in vitro and in vivo profile. Life sciences, 1993, Volume: 52, Issue:5-6 Topics: Acetylcholine; Animals; Brain; CHO Cells; Cricetinae; Ganglia, Sympathetic; Guinea Pigs; Ileum; Imidazoles; Male; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Pilocarpine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Thiophenes	1993

Article

Year

Muscarinic activity of the thiolactone, lactam, lactol, and thiolactol analogues of pilocarpine and a hypothetical model for the binding of agonists to the m1 receptor.

Journal of medicinal chemistry, 1992, Volume: 35, Issue:1

Topics: Animals; Binding, Competitive; Crystallography; Guinea Pigs; Lactams; Male; Mice; Models, Biological; Parasympathomimetics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds

1992

SDZ ENS 163 a novel pilocarpine like drug: pharmacological in vitro and in vivo profile.

Life sciences, 1993, Volume: 52, Issue:5-6

Topics: Acetylcholine; Animals; Brain; CHO Cells; Cricetinae; Ganglia, Sympathetic; Guinea Pigs; Ileum; Imidazoles; Male; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Pilocarpine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Thiophenes

1993