scutellarein has been researched along with chloromethyl-methyl-ether* in 1 studies
1 other study(ies) available for scutellarein and chloromethyl-methyl-ether
Article | Year |
---|---|
A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin.
In this paper, a new and efficient synthesis of 6-O-methylscutellarein (3), the major metabolite of the natural medicine scutellarin, is reported. Two hydroxyl groups at C-4' and C-7 in 2 were selectively protected by chloromethyl methyl ether after the reaction conditions were optimized, then 6-O-methyl-scutellarein (3) was produced in high yield after methylation of the hydroxyl group at C-6 and subsequent deprotection of the two methyl ether groups. Topics: Apigenin; Biotransformation; Flavones; Glucuronates; Humans; Methyl Ethers; Methylation; Solutions | 2015 |