scutellarein has been researched along with caffeic-acid* in 2 studies
2 other study(ies) available for scutellarein and caffeic-acid
Article | Year |
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CE-DAD Determination of Scutellarein and Caffeic Acid in Abelia triflora Crude Extract.
A precise, accurate, selective and sensitive capillary electrophoresis method using a diode array detector was developed for the first time for the determination of both scutellarein (SLN) and caffeic acid (CAA) in prepared Abelia triflora extract. Electrophoretic analysis was performed using a background electrolyte solution consisting of borax buffer (40 mM, pH 9.2) and a 200-nm detection wavelength. This method was fully validated according to The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines. The method was linear in the concentration range 2.5-100 μg/mL and it allowed the determination of both compounds with high degree of recovery (%Er < 2%) and intra-day and inter-day precision (relative standard deviation values <2%) and method robustness was also assessed by the low values of %RSD < 2% obtained after small deliberate changes in the method parameters. The contents of SLN and CAA were calculated using both the external standard and standard addition methods. Analysis of the ethyl acetate fraction of A. triflora revealed that SLN and CAA were found in concentrations of 0.46 mg/g and 2.10 mg/g, respectively, in the ethyl acetate fraction and 0.29 and 1.32 mg%, respectively, in the dry plant leaves. Topics: Acetates; Apigenin; Borates; Buffers; Caffeic Acids; Caprifoliaceae; Electrolytes; Electrophoresis, Capillary; Plant Extracts | 2018 |
Study of Sedative Tea Phytocomplex within the Framework of Studies Aimed at Creation of a Rectal Dosage Form with Antihistaminic Effect.
We designed a new complex drug with antiallergic effect containing, in addition to the main component loratadine, a phytocomplex for an extra therapeutic effect. A collection of plants with sedative activity is chosen and the optimal agent for extraction of bioactive compounds (40% ethanol) and optimal degree of plant fragmentation are determined. Chemical composition of the sedative tea is evaluated by reverse phase HPLC. The marker components of the species are detected: xanthohumol and isoxanthohumol - Humulus lupulus cone components, Mentha piperita rosmarinic acid, and scutellareine, Menyanthes trifolia element - quercetin-3-rutinoside, and caffeic acid. Standardization of the species by the absolute graduation method in conversion to quercetin-3-rutinoside is suggested. Topics: Apigenin; Caffeic Acids; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Ethanol; Flavonoids; Histamine H1 Antagonists; Humans; Humulus; Mentha piperita; Phytochemicals; Plant Extracts; Propiophenones; Rosmarinic Acid; Rutin; Solvents; Suppositories; Xanthones | 2017 |