Page last updated: 2024-08-16

scriptaid and trichostatin a

scriptaid has been researched along with trichostatin a in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (33.33)	29.6817
2010's	17 (56.67)	24.3611
2020's	3 (10.00)	2.80

Authors

Authors	Studies
Abou-Khalil, E; Allan, M; Beaulieu, C; Bernstein, N; Besterman, JM; Bouchain, G; Delorme, D; Fournel, M; Frechette, S; Kalita, A; Leit, S; Li, Z; MacLeod, AR; Moradei, O; Trachy-Bourget, MC; Vaisburg, A; Wang, J; Woo, SH; Yan, PT	1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y	1
Balch, WE; Frizzell, RA; Gentzsch, M; Gottesfeld, JM; Herman, D; Hoch, B; Hutt, DM; Kellner, W; Kelly, JW; Lukacs, GL; Manning, G; Matsumura, Y; Matteson, J; Noel, S; Okiyoneda, T; Pilewski, JM; Riordan, JR; Rodrigues, AP; Schmidt, A; Skach, WR; Sorscher, EJ; Thomas, PJ; Yates, JR	1
Bradner, JE; Grachan, ML; Greenberg, EF; Haggarty, SJ; Mazitschek, R; Warnow, T; West, N	1
Cheng, F; Dong, N; Huang, J; Jiang, X; Li, J; Lin, P; Liu, M; Lu, W; Ouyang, P; Tang, Y; Wu, D; Wu, Z; Xu, Z; Yao, X; Zeng, M; Zhang, C; Zou, S	1
Forgione, M; Hailu, GS; Mai, A; Robaa, D; Rotili, D; Sippl, W	1
Ballante, F; Marshall, GR; Reddy, DR; Zhou, NJ	1
Al-Mouhammad, H; Alami, M; Bauvais, C; Benihoud, K; Bignon, J; Bollot, G; Borgel, D; Dubois, J; Feuillard, J; Hamze, A; Jayat-Vignoles, C; Kasselouri, A; Lamaa, D; Levaique, H; Lin, HP; Ouaissi, M; Pamlard, O; Saller, F; Souce, M; Zig, L	1
Ashton, TD; Devlin, M; Fleming, CL; Gibert, Y; Leslie, KG; Natoli, A; New, EJ; Pfeffer, FM; Schreuders, J; Yoganantharajah, P	1
Brindisi, M; Brogi, S; Butini, S; Campiani, G; Gemma, S; Saraswati, AP	1
Alami, M; Apcher, S; Askenatzis, L; Balcerowiak, C; Baschieri, F; Bauvais, C; Bignon, J; Blanchard, V; Bollot, G; Deroussent, A; Ducellier, S; Hamze, A; Hauguel, C; Ibrahim, N; Lafanechère, L; Laisne, MC; Lamaa, D; Letribot, B; Levaique, H; Michallet, S; Montagnac, G; Nascimento, M; Papot, S; Prost, B; Provot, O; Renko, D; Tran, C	1
Kern, SE; Ryu, B; Sohn, TA; Su, GH	1
Cao, H; Jung, M; Stamatoyannopoulos, G	1
Baliga, BS; Hunter, R; Johnson, J; McElveen, R; Pace, BS; Qian, XH	1
Berenji, K; Hill, JA; Kong, Y; Lu, G; Olson, EN; Rothermel, BA; Tannous, P	1
Cassell, M; Lindsay, DS; Mitchell, SM; Reilly, CM; Strobl, JS	1
Arnason, TG; Chik, CL; Dukewich, WG; Ho, AK; Price, DM; Steinberg, N	1
Han, SB; Lee, JK	1
Dagtas, AS; Edens, RE; Gilbert, KM	1
Kubota, N; Kuribayashi, T; Ohara, M; Sora, S	1
Hao, Y; Murphy, CN; Prather, RS; Rieke, A; Ross, JW; Samuel, MS; Spate, LD; Walters, EM; Zhao, J	1
Akiba, N; Akiba, Y; Baker, H; Cave, JW; Langley, B; Ratan, RR	1
Akagi, S; Fukunari, K; Kaneda, M; Matsukawa, K; Mizutani, E; Takahashi, S; Watanabe, S	1
Li, W; Lou, TF; Mackie, A; Pace, B; Ramakrishnan, V; Sivanand, S; Zein, S	1
Wan, YJ; Yang, H; Zhan, Q	1
Bui, HT; Kim, JH; Park, JY; Park, MR; Seo, HJ; Thuan, NV; Wakayama, T	1
Chang, WF; Chen, CH; Chen, YE; Cheng, WT; Du, F; Ju, JC; Lin, TA; Liu, CC; Su, HY; Sung, LY; Wu, SC; Xu, J	1
Kim, YH; Lee, JK	1
Alavanos, A; Andreatos, N; Angelou, A; Antoniou, EA; Apostolou, KG; Athanasiou, A; Damaskos, C; Damaskou, Z; Daskalopoulou, A; Diamantis, E; Dimitroulis, D; Garmpi, A; Garmpis, N; Kalampokas, E; Kalampokas, T; Kontzoglou, K; Kostakis, A; Lavaris, A; Mantas, D; Margonis, GA; Markatos, K; Moschos, MM; Nikiteas, N; Nonni, A; Perrea, D; Sampani, A; Schizas, D; Spartalis, E; Spartalis, M; Tsivelekas, K; Tsourouflis, G; Valsami, S	1
Awada, R; Breton, D; Brulard, E; de Faria Maraschin, S; Etienne, H; Froger, S; Verdier, D	1

Reviews

2 review(s) available for scriptaid and trichostatin a

Article	Year
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives. Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12 Topics: Animals; Antiparasitic Agents; Drug Repositioning; Helminth Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leishmania; Plasmodium; Protozoan Proteins; Schistosoma; Toxoplasma; Trypanosoma	2017
Targeting histone deacetylases in endometrial cancer: a paradigm-shifting therapeutic strategy? European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:4 Topics: Antineoplastic Agents; Endometrial Neoplasms; Endometrium; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Hydroxylamines; Quinolines	2018

Other Studies

28 other study(ies) available for scriptaid and trichostatin a

Article	Year
(2-amino-phenyl)-amides of omega-substituted alkanoic acids as new histone deacetylase inhibitors. Bioorganic & medicinal chemistry letters, 2004, Jan-05, Volume: 14, Issue:1 Topics: Amides; Cell Cycle; Cell Line, Tumor; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans	2004
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26 Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase	2008
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nature chemical biology, 2010, Volume: 6, Issue:1 Topics: Animals; Bronchi; Cell Membrane; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Silencing; Histone Deacetylases; Humans; Hydroxamic Acids; Mutation; Protein Denaturation; Protein Folding; RNA, Small Interfering; Vorinostat	2010
Chemical phylogenetics of histone deacetylases. Nature chemical biology, 2010, Volume: 6, Issue:3 Topics:	2010
Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis. Journal of medicinal chemistry, 2017, 03-09, Volume: 60, Issue:5 Topics: Acute Lung Injury; Animals; Epoxide Hydrolases; Female; Histone Deacetylase Inhibitors; Idiopathic Pulmonary Fibrosis; Leukotriene B4; Mice; Mice, Inbred C57BL; Neutrophils	2017
Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy. Bioorganic & medicinal chemistry, 2017, 04-01, Volume: 25, Issue:7 Topics: Animals; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; In Vitro Techniques; Molecular Docking Simulation; Molecular Structure; Quantitative Structure-Activity Relationship; Schistosoma mansoni	2017
Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4. Journal of medicinal chemistry, 2018, Aug-09, Volume: 61, Issue:15 Topics: Antineoplastic Agents; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Design; HCT116 Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; K562 Cells; Protein Conformation; Stilbenes; Tubulin	2018
Highly fluorescent and HDAC6 selective scriptaid analogues. European journal of medicinal chemistry, 2019, Jan-15, Volume: 162 Topics: Animals; Blood Vessels; Cytoplasm; Diagnostic Imaging; Fluorescence; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Hydroxylamines; Quinolines; Zebrafish	2019
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases. Journal of medicinal chemistry, 2020, 01-09, Volume: 63, Issue:1 Topics: Animals; Biomarkers; Cell Line; Epigenesis, Genetic; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Mice; Protein Processing, Post-Translational; Rare Diseases	2020
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors. European journal of medicinal chemistry, 2022, Oct-05, Volume: 240 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Polymerization; Quinolines; Repressor Proteins; Tubulin	2022
A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. Cancer research, 2000, Jun-15, Volume: 60, Issue:12 Topics: Cell Survival; Chemistry, Organic; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genes, Reporter; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Immunoblotting; Luciferases; Organic Chemistry Phenomena; Quinolines; Signal Transduction; Smad4 Protein; Trans-Activators; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured	2000
Induction of human gamma globin gene expression by histone deacetylase inhibitors. Blood, 2004, Jan-15, Volume: 103, Issue:2 Topics: Amides; Enzyme Inhibitors; Gene Expression Regulation; Globins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Peptides; Quinolines	2004
Fetal hemoglobin induction by the histone deacetylase inhibitor, scriptaid. Cellular and molecular biology (Noisy-le-Grand, France), 2005, Sep-05, Volume: 51, Issue:2 Topics: Anemia, Sickle Cell; Animals; Butyrates; Enzyme Inhibitors; Erythroid Precursor Cells; Fetal Hemoglobin; Gene Expression Regulation; Gene Silencing; Globins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Imidazoles; K562 Cells; Mice; Mice, Transgenic; p38 Mitogen-Activated Protein Kinases; Pyridines; Quinolines; RNA, Messenger; Signal Transduction	2005
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation, 2006, Jun-06, Volume: 113, Issue:22 Topics: Acetylation; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Hydroxylamines; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptides; Protein Isoforms; Quinolines; Repressor Proteins; Time Factors; Ultrasonography; Ventricular Function	2006
Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. The Journal of parasitology, 2007, Volume: 93, Issue:3 Topics: Animals; Antiprotozoal Agents; Butyrates; Cattle; Cell Line; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Inhibitory Concentration 50; Niacinamide; Parasitic Sensitivity Tests; Phenylbutyrates; Quinolines; Toxoplasma; Valproic Acid; Vitamin B Complex; Vorinostat	2007
Acetylation of histone H3 and adrenergic-regulated gene transcription in rat pinealocytes. Endocrinology, 2007, Volume: 148, Issue:10 Topics: Acetylation; Adrenergic Agents; Adrenergic alpha-Agonists; Animals; Arylalkylamine N-Acetyltransferase; Cell Cycle Proteins; Cells, Cultured; Cyclic AMP Response Element Modulator; Drug Administration Schedule; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Hydroxylamines; Immediate-Early Proteins; Melatonin; Norepinephrine; Phosphoprotein Phosphatases; Pineal Gland; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-fos; Quinolines; Rats; RNA, Messenger; Transcription, Genetic	2007
Anti-inflammatory effect of Trichostatin-A on murine bone marrow-derived macrophages. Archives of pharmacal research, 2009, Volume: 32, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hydroxylamines; Inflammation Mediators; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Quinolines; RNA, Messenger; Time Factors	2009
Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells. International immunopharmacology, 2009, Volume: 9, Issue:11 Topics: Acetylation; Animals; Butyrates; CD4-Positive T-Lymphocytes; Cells, Cultured; Clonal Anergy; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Induction; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxylamines; Mice; Mice, Inbred C57BL; Okadaic Acid; Quinolines; Th1 Cells	2009
Scriptaid, a novel histone deacetylase inhibitor, enhances the response of human tumor cells to radiation. International journal of molecular medicine, 2010, Volume: 25, Issue:1 Topics: Antigens, Nuclear; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Breaks, Double-Stranded; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Ku Autoantigen; Quinolines; Radiation; Radiation-Sensitizing Agents	2010
Histone deacetylase inhibitors improve in vitro and in vivo developmental competence of somatic cell nuclear transfer porcine embryos. Cellular reprogramming, 2010, Volume: 12, Issue:1 Topics: Acetylation; Animals; Animals, Outbred Strains; Blastocyst; Cloning, Organism; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo Transfer; Embryo, Mammalian; Embryonic Development; Enzyme Activation; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hydroxylamines; Nuclear Transfer Techniques; Quinolines; Sus scrofa; Time Factors	2010
Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. Biochemical and biophysical research communications, 2010, Mar-19, Volume: 393, Issue:4 Topics: Animals; Butyrates; Cell Movement; Green Fluorescent Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hydroxylamines; Mice; Mice, Transgenic; Neurons; Olfactory Bulb; Prosencephalon; Quinolines; Stem Cells; Tyrosine 3-Monooxygenase	2010
Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos. The Journal of reproduction and development, 2011, Volume: 57, Issue:1 Topics: Acetylation; Animals; Blastocyst; Cattle; Cell Line; Cloning, Organism; Ectogenesis; Embryo Culture Techniques; Fibroblasts; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Hydroxylamines; Nuclear Transfer Techniques; Oocytes; Osmolar Concentration; Quinolines; Time Factors	2011
Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line. Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:11 Topics: Antigens, Surface; Benzamides; beta-Globins; Butyrates; Cell Differentiation; Cell Line, Tumor; Erythroid Precursor Cells; Fetal Hemoglobin; gamma-Globins; Gene Expression; Humans; Hydroxamic Acids; Hydroxylamines; Hydroxyurea; Imatinib Mesylate; K562 Cells; Piperazines; Pyrimidines; Quinolines; RNA, Messenger; Signal Transduction; Transcription Factors; Vorinostat	2010
Enrichment of Nur77 mediated by retinoic acid receptor β leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors. Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:3 Topics: Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Fenretinide; Hep G2 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Liver Neoplasms; Nuclear Receptor Subfamily 4, Group A, Member 1; Quinolines; Reactive Oxygen Species; Receptors, Retinoic Acid; RNA, Messenger	2011
Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. Biology of reproduction, 2011, Volume: 85, Issue:5 Topics: Animals; Cell Nucleolus; Cloning, Organism; Embryonic Development; Enzyme Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hydroxylamines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Models, Animal; Nuclear Transfer Techniques; Quinolines; RNA, Ribosomal; Transcriptional Activation	2011
Synergistic effect of trichostatin A and scriptaid on the development of cloned rabbit embryos. Theriogenology, 2013, Volume: 79, Issue:9 Topics: Animals; Cloning, Organism; Embryo Culture Techniques; Female; Gene Expression Regulation, Developmental; Hydroxamic Acids; Hydroxylamines; Male; Octamer Transcription Factor-3; Quinolines; Rabbits	2013
Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression. Cellular immunology, 2017, Volume: 316 Topics: Animals; Butyric Acid; Cell Differentiation; Cell Movement; Cells, Cultured; Chemokine CCL3; Dendritic Cells; Down-Regulation; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxylamines; Mice; Mice, Inbred C57BL; Quinolines; Receptors, CCR1	2017
An innovative automated active compound screening system allows high-throughput optimization of somatic embryogenesis in Coffea arabica. Scientific reports, 2020, 01-21, Volume: 10, Issue:1 Topics: Automation, Laboratory; Coffea; High-Throughput Screening Assays; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxylamines; Miniaturization; Pilot Projects; Plant Cells; Plant Somatic Embryogenesis Techniques; Quinolines; Reproducibility of Results; Seeds	2020