Page last updated: 2024-09-02

schizandrin b and schizandrol b

schizandrin b has been researched along with schizandrol b in 28 studies

Compound Research Comparison

Studies
(schizandrin b)
Trials
(schizandrin b)
Recent Studies (post-2010)
(schizandrin b)
Studies
(schizandrol b)
Trials
(schizandrol b)
Recent Studies (post-2010) (schizandrol b)
3211218116058

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.86)18.7374
1990's1 (3.57)18.2507
2000's3 (10.71)29.6817
2010's17 (60.71)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Song, WZ; Tong, YY; Wang, K1
Liu, GT1
Li, Y; Liu, GT1
Cresteil, T; Le Provost, E; Lesca, P; Liu, KT1
Lesca, P; Liu, KT2
Kim, SH; Kim, SR; Kim, YC; Koo, KA; Lee, MK; Lee, NG; Markelonis, GJ; Oh, TH; Sung, SH; Yang, JH1
Huang, M; Jin, J; Liu, GT; Sun, H1
Avula, B; Choi, YW; Khan, IA; Khan, SI; Madgula, VL; Pullela, SV; Walker, LA1
Choi, IW; Choi, YH; Choi, YW; Hwang, WD; Jeong, YK; Jin, CY; Kim, GY; Kim, JH; Kim, SG; Kim, SK; Lee, YJ; Park, C; Park, DJ1
Gao, Q; Li, X; Luo, H; Weng, W; Xiao, F1
Chen, Q; Cheng, NN; Li, YL; Wang, YM; Wu, YJ1
Guan, M; Li, T; Liu, Y; Sheng, Y; Wang, Y; Yuan, G1
Han, Y; Sun, H; Wang, X; Wei, W; Wu, F; Zhang, A1
Bi, K; Chen, X; Fan, R; Geng, L; He, B; Jia, Y; Li, Q; Su, D; Wei, B; Zhao, L1
Bi, HC; Chen, X; Huang, M; Li, JL; Qin, XL; Wang, CX; Wang, XD; Wang, Y; Xue, XP; Yang, H; Zhong, GP1
Bae, YS; Choi, YW; Ko, MJ; Lee, SJ; Park, SY1
Chen, L; Chen, T; Ding, P; Li, XK; Song, X; Wang, B1
Cheng, Q; Ji, B; Liu, J; Wang, O; Wang, Y; Zhao, L; Zhou, F1
Bi, H; Chen, P; Fan, X; Huang, M; Jiang, Y; Tan, H; Wang, Y; Zeng, H1
Liu, CH; Liu, S; Tao, YY; Yang, T; Zheng, TH1
Bradbury, EJ; Brown, CF; Lyles, JT; Nelson, K; Pierce, ST; Quave, CL; Tyler, P1
Cheon, SM; Cho, HY; Ham, SH; Kim, SJ; Ko, SM; Kwon, YD; Lee, YB; Shin, H1
Cheng, X; Ding, XY; Ji, JD; Lu, TL; Mao, CQ; Su, LL; Wang, LJ; Zhang, J1
Fang, L; Guo, X; Han, X; Leng, A; Li, D; Peng, J; Qi, Y; Sun, C; Wang, R; Yin, L1
Du, Z; Fu, Q; Hu, CM; Hu, RX; Yang, K; Zhang, X1
Ahn, SJ; In, S; Kim, E; Kim, HJ; Lee, A; Min, SS1
Bi, K; Li, Q; Li, S; Xu, H; Yang, P; Zhang, Q; Zhang, Y1

Other Studies

28 other study(ies) available for schizandrin b and schizandrol b

ArticleYear
[Determination of the active ingredients in Chinese drug wuweizi (Schisandra chinensis) by TLC-densitometry].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:1

    Topics: Chromatography, Thin Layer; Cyclooctanes; Densitometry; Dioxoles; Drugs, Chinese Herbal; Lignans; Polycyclic Compounds

1990
Pharmacological actions and clinical use of fructus schizandrae.
    Chinese medical journal, 1989, Volume: 102, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Drugs, Chinese Herbal; Hepatitis B; Humans; Lignans; Lipid Peroxidation; Mice; Microsomes, Liver; Polycyclic Compounds; Rats

1989
[Effects of schizandrins and diphenyl dimethyl bicarboxylate on enzymes of liver smooth and rough endoplasmic reticula in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:6

    Topics: Animals; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Endoplasmic Reticulum; Lignans; Liver; Male; Polycyclic Compounds; Rats; Rats, Inbred Strains

1987
Specific evidence that schizandrins induce a phenobarbital-like cytochrome P-450 form separated from rat liver.
    Biochemical and biophysical research communications, 1981, Dec-31, Volume: 103, Issue:4

    Topics: Animals; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxolanes; Dioxoles; Hydrocarbons, Chlorinated; Immunodiffusion; Lignans; Male; Microsomes, Liver; Phenobarbital; Polycyclic Compounds; Rats; Rats, Inbred Strains

1981
Pharmacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism and mutagenicity.
    Chemico-biological interactions, 1982, Volume: 39, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; In Vitro Techniques; Lignans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Microsomes, Liver; Mutagens; NADP; Oxidation-Reduction; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Inbred Strains

1982
Pharmacological properties of Dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae Chinensis III. Inhibitory effects on carbon tetrachloride-induced lipid peroxidation, metabolism and covalent binding of carbon tetrachloride to lipids.
    Chemico-biological interactions, 1982, Jul-15, Volume: 41, Issue:1

    Topics: Animals; Carbon Tetrachloride; China; Cyclooctanes; Dioxoles; Lignans; Lipid Metabolism; Lipid Peroxides; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; NADP; Oxygen Consumption; Plants, Medicinal; Polycyclic Compounds

1982
Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity.
    Journal of neuroscience research, 2004, May-01, Volume: 76, Issue:3

    Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Glutamic Acid; Intracellular Fluid; Lignans; Neurons; Neuroprotective Agents; Neurotoxins; Peroxides; Phytotherapy; Plant Extracts; Polycyclic Compounds; Rats; Schisandra

2004
Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:6

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cyclooctanes; Dioxoles; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Fruit; Genes, MDR; Humans; Lignans; Mice; Mice, Nude; Neoplasm Proteins; Phytotherapy; Plant Preparations; Polycyclic Compounds; Protein Kinase C; Schisandra; Xenograft Model Antitumor Assays

2008
Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - an in-vitro model of intestinal transport.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Chromatography, High Pressure Liquid; Cyclooctanes; Diffusion; Dioxoles; Drug Interactions; Humans; Intestinal Mucosa; Intestines; Lignans; Medicine, Chinese Traditional; Models, Biological; Multidrug Resistance-Associated Proteins; Permeability; Plant Extracts; Polycyclic Compounds; Schisandra

2008
Apoptosis induction of human leukemia U937 cells by gomisin N, a dibenzocyclooctadiene lignan, isolated from Schizandra chinensis Baill.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 3; Caspase Inhibitors; Cell Proliferation; Cell Survival; Cyclin D1; Cyclooctanes; Cytochromes c; Dioxoles; DNA Fragmentation; Flow Cytometry; Fruit; G1 Phase; Humans; Lignans; Mitochondria; Polycyclic Compounds; Schisandra; U937 Cells

2010
[Research on liposoluble ingredients of Quchiling].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:1

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Brain; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Female; Gas Chromatography-Mass Spectrometry; Lignans; Male; Polycyclic Compounds; Rats; Rats, Sprague-Dawley

2010
[Dual effects of extract of Schisandra chinensis Baill on rat hepatic CYP3A].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:9

    Topics: Animals; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hepatocytes; Inhibitory Concentration 50; Lignans; Male; Microsomes, Liver; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Schisandra

2010
Simultaneous and rapid determination of main lignans in different parts of Schisandra sphenanthera by micellar electrokinetic capillary chromatography.
    Molecules (Basel, Switzerland), 2011, May-03, Volume: 16, Issue:5

    Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclooctanes; Dioxoles; Lignans; Polycyclic Compounds

2011
Pharmacokinetic study of schisandrin, schisandrol B, schisantherin A, deoxyschisandrin, and schisandrin B in rat plasma after oral administration of Shengmaisan formula by UPLC-MS.
    Journal of separation science, 2013, Volume: 36, Issue:3

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Male; Polycyclic Compounds; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization

2013
Development of a UFLC-MS/MS method for simultaneous determination of six lignans of Schisandra chinensis (Turcz.) Baill. in rat plasma and its application to a comparative pharmacokinetic study in normal and insomnic rats.
    Journal of pharmaceutical and biomedical analysis, 2013, Apr-15, Volume: 77

    Topics: Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Male; Medicine, Chinese Traditional; Polycyclic Compounds; Random Allocation; Rats; Rats, Sprague-Dawley; Schisandra; Sensitivity and Specificity; Sleep Initiation and Maintenance Disorders; Tandem Mass Spectrometry

2013
In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) on the CYP3A/P-glycoprotein-mediated absorption and metabolism of tacrolimus.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:1

    Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Drugs, Chinese Herbal; Humans; Lignans; Male; Microsomes, Liver; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Tablets; Tacrolimus

2014
Comparison of anti-inflammatory potential of four different dibenzocyclooctadiene lignans in microglia; action via activation of PKA and Nrf-2 signaling and inhibition of MAPK/STAT/NF-κB pathways.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:4

    Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cyclic AMP-Dependent Protein Kinases; Cyclooctanes; Dioxoles; Lignans; Lipopolysaccharides; MAP Kinase Signaling System; Mice, Inbred ICR; Microglia; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Polycyclic Compounds; Reactive Oxygen Species; STAT Transcription Factors; Toll-Like Receptor 2

2014
[Effect of forchlorfenuron on fruit morphology and lignans content of Schisandra chinensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:9

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Fruit; Lignans; Phenylurea Compounds; Polycyclic Compounds; Pyridines

2014
Hepatoprotective effect of Schisandra chinensis (Turcz.) Baill. lignans and its formula with Rubus idaeus on chronic alcohol-induced liver injury in mice.
    Food & function, 2014, Volume: 5, Issue:11

    Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Lignans; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred ICR; Plant Extracts; Polycyclic Compounds; Rubus; Schisandra

2014
Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
    Chemico-biological interactions, 2015, Apr-25, Volume: 231

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dioxoles; Lignans; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Polycyclic Compounds; Protective Agents; Schisandra

2015
Comparative pharmacokinetics and tissue distribution profiles of lignan components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe.
    Journal of ethnopharmacology, 2015, May-26, Volume: 166

    Topics: Administration, Oral; Animals; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Kidney; Lignans; Liver; Liver Cirrhosis; Male; Polycyclic Compounds; Rats; Rats, Wistar; Tissue Distribution

2015
Comparative Phytochemical Analysis of Chinese and Bay Starvine (Schisandra spp.): Potential for Development as a New Dietary Supplement Ingredient.
    Journal of dietary supplements, 2017, Nov-02, Volume: 14, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dietary Supplements; Dioxoles; Fruit; Lignans; Medicine, Chinese Traditional; Phenols; Phytochemicals; Plant Extracts; Polycyclic Compounds; Schisandra; Spectroscopy, Fourier Transform Infrared; Tannins

2017
A sensitive UHPLC-MS/MS method for the simultaneous quantification of three lignans in human plasma and its application to a pharmacokinetic study.
    Journal of separation science, 2017, Volume: 40, Issue:17

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Humans; Lignans; Polycyclic Compounds; Reproducibility of Results; Tandem Mass Spectrometry

2017
[Analysis of lignans and their metabolites derived from Schisandra chinensis and vinegar Schisandra chinensis in rats’ plasma, bile, urine and faeces based on UHPLC-QTOF/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:10

    Topics: Acetic Acid; Animals; Bile; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Feces; Lignans; Liver Diseases, Alcoholic; Plasma; Polycyclic Compounds; Rats; Schisandra; Urine

2016
Simultaneous quantification of Schisandrin B enantiomers in rat plasma by chiral LC-MS/MS: Application in a stereoselective pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2018, Sep-10, Volume: 159

    Topics: Animals; Anti-Inflammatory Agents; Chromatography, Liquid; Cyclooctanes; Dioxoles; Lignans; Male; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tandem Mass Spectrometry

2018
Evaluation of the inhibition of human carboxylesterases (CESs) by the active ingredients from
    Xenobiotica; the fate of foreign compounds in biological systems, 2019, Volume: 49, Issue:11

    Topics: Carboxylesterase; Carboxylic Ester Hydrolases; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Humans; Lignans; Microsomes, Liver; Molecular Docking Simulation; Polycyclic Compounds; Schisandra

2019
Determination of 12 herbal compounds for estimating the presence of Angelica Gigas Root, Cornus Fruit, Licorice Root, Pueraria Root, and Schisandra Fruit in foods by LC-MS/MS.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2020, Volume: 37, Issue:9

    Topics: Benzopyrans; Butyrates; Chromatography, Liquid; Coumarins; Cyclooctanes; Dioxoles; Flavanones; Food Analysis; Fruit; Glucosides; Glycosides; Glycyrrhizic Acid; Herbal Medicine; Iridoids; Isoflavones; Lignans; Plant Roots; Plants, Medicinal; Polycyclic Compounds; Tandem Mass Spectrometry

2020
A multidimensional strategy for uncovering comprehensive quality markers of Schisandra chinensis (Turcz.) Baill based on pharmacodynamics and chemical properties.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Biomarkers; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Polycyclic Compounds; Rats; Schisandra

2022