Page last updated: 2024-09-02

schizandrin b and nifedipine

schizandrin b has been researched along with nifedipine in 2 studies

Compound Research Comparison

Studies
(schizandrin b)
Trials
(schizandrin b)
Recent Studies (post-2010)
(schizandrin b)
Studies
(nifedipine)
Trials
(nifedipine)
Recent Studies (post-2010) (nifedipine)
321121816,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomyschizandrin b (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Chen, AC; Chen, WC; Lu, CK; Ueng, YF; Wang, HJ1
Chia-Hui Tan, E; Chiang, TY; Lee, IJ; Ueng, YF; Wang, HJ; Wang, YC; Yun, CH1

Other Studies

2 other study(ies) available for schizandrin b and nifedipine

ArticleYear
Shenmai-Yin decreased the clearance of nifedipine in rats: The involvement of time-dependent inhibition of nifedipine oxidation.
    Journal of food and drug analysis, 2019, Volume: 27, Issue:1

    Topics: Animals; Cyclooctanes; Cytochrome P-450 CYP3A; Drug Interactions; Drugs, Chinese Herbal; Humans; Lignans; Male; Nifedipine; Polycyclic Compounds; Rats; Rats, Sprague-Dawley

2019
Effects of Shengmai San on key enzymes involved in hepatic and intestinal drug metabolism in rats.
    Journal of ethnopharmacology, 2021, May-10, Volume: 271

    Topics: Animals; Biomarkers; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Combinations; Drugs, Chinese Herbal; Ginsenosides; Glucuronosyltransferase; Glutathione Transferase; Herb-Drug Interactions; Intestines; Lignans; Liver; Male; Microsomes; NAD(P)H Dehydrogenase (Quinone); Nifedipine; Oxidation-Reduction; Polycyclic Compounds; Rats, Sprague-Dawley; Saponins; Spirostans

2021