Page last updated: 2024-08-22

schizandrin and schizandrin a

schizandrin has been researched along with schizandrin a in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.25)18.7374
1990's0 (0.00)18.2507
2000's9 (28.13)29.6817
2010's19 (59.38)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Choi, YW; Ferreira, D; Khan, IA; Khan, SI; Srinivas, PV; Takamatsu, S; Zhao, J1
Hu, X; Li, L; Lu, Q; Pan, Q; Sun, M1
Bae, K; Chung, HJ; Hong, JY; Hung, TM; Kang, SS; Kang, YJ; Kim, SJ; Kim, YS; Lee, SK; Min, HY; Park, EJ; Woo, ER; Youn, UJ1
Adámková, L; Carnecká, M; Humpa, O; Páchniková, G; Porubová Koubíková, L; Slanina, J; Slaninová, I; Smejkal, K1
Cao, YF; Dou, TY; Feng, L; Ge, GB; Hao, DC; He, YQ; Hong, JY; Wang, P; Wu, JJ; Yang, L1
Hu, M; Li, J; Ma, X; Wang, H1
Liu, GT1
Lesca, P; Liu, KT1
Kim, SH; Kim, SR; Kim, YC; Koo, KA; Lee, MK; Lee, NG; Markelonis, GJ; Oh, TH; Sung, SH; Yang, JH1
Li, JQ; Li, P; Mu, J; Zhang, LQ; Zhu, XL1
Huang, M; Jin, J; Liu, GT; Sun, H1
Caichompoo, W; Gao, HJ; Hou, TT; Qin, LP; Zhang, QY; Zhou, XJ1
Huang, X; Liu, SY; Liu, ZQ; Song, FR1
Hu, Y; Sun, R; Yu, J; Zhou, J1
Liu, TT; Ma, CH; Wang, SY; Yang, L; Zhang, RR; Zu, YG1
Guan, M; Li, T; Liu, Y; Sheng, Y; Wang, Y; Yuan, G1
Liu, TT; Ma, CH; Yang, FJ; Yang, L; Zhang, L; Zhang, ZH; Zhao, CJ; Zu, YG1
Dong, JP; He, FC; Li, SX; Liu, WZ; Su, RQ; Zhao, ZQ1
Han, Y; Sun, H; Wang, X; Wei, W; Wu, F; Zhang, A1
Chen, H; Huang, ZJ; Lu, TL; Mao, CQ; Song, Y; Sun, Y; Wu, XY; Xu, B; Zhou, Y1
Chen, H; Hu, JP; Li, Y; Sheng, L; Wang, BL1
Dai, G; Ji, D; Li, L; Lu, T; Mao, C; Sun, Y; Wu, X; Xu, B; Yin, F; Zhou, Y1
Hu, XL; Liu, ZQ; Pi, ZF; Song, FR; Yu, XL1
Cai, Q; Du, SS; Zheng, LS1
Ekiert, H; Kisiel, W; Szewczyk, A; Szopa, A1
An, LB; Cui, L; Dong, PP; Fang, ZZ; Gonzalez, FJ; Li, WT; Song, JH; Sun, XY; Wang, LX; Wu, X; Zhang, YY; Zhao, DW1
Liu, X; Liu, Y; Wang, Y; Zhang, D; Zhang, W1
Feng, YL; Li, W; Liu, KY; Liu, YL; Song, YG; Su, D; Yang, LJ1
Cheng, X; Ding, XY; Ji, JD; Lu, TL; Mao, CQ; Su, LL; Wang, LJ; Zhang, J1
Cao, JQ; Deng, ZW; Du, SS; Geng, ZF; Guo, SS; Liang, JY; Pang, X; Wang, Y1
Bi, K; Gao, H; Li, Q; Liu, H; Liu, R; Lv, X; Xu, H; Zhang, M; Zhang, Q; Zhang, Y1
Bi, K; Li, Q; Li, S; Xu, H; Yang, P; Zhang, Q; Zhang, Y1

Reviews

1 review(s) available for schizandrin and schizandrin a

ArticleYear
Discovery of traditional Chinese medicine monomers and their synthetic intermediates, analogs or derivatives for battling P-gp-mediated multi-drug resistance.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Discovery; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional

2018

Other Studies

31 other study(ies) available for schizandrin and schizandrin a

ArticleYear
Schisandrene, a dibenzocyclooctadiene lignan from Schisandra chinensis: structure-antioxidant activity relationships of dibenzocyclooctadiene lignans.
    Journal of natural products, 2006, Volume: 69, Issue:3

    Topics: Antioxidants; Cyclooctanes; Korea; Lignans; Molecular Structure; Plants, Medicinal; Schisandra; Structure-Activity Relationship

2006
Dibenzocyclooctadiene lignans: a class of novel inhibitors of multidrug resistance-associated protein 1.
    Life sciences, 2007, Jan-30, Volume: 80, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cyclooctanes; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Lignans; Multidrug Resistance-Associated Proteins

2007
Antiproliferative effects of dibenzocyclooctadiene lignans isolated from Schisandra chinensis in human cancer cells.
    Bioorganic & medicinal chemistry letters, 2008, Jan-15, Volume: 18, Issue:2

    Topics: Cell Line, Tumor; Cell Proliferation; Cyclooctanes; Humans; Lignans; Molecular Structure; Schisandra

2008
Identification of key structural characteristics of Schisandra chinensis lignans involved in P-glycoprotein inhibition.
    Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cyclooctanes; Doxorubicin; G2 Phase Cell Cycle Checkpoints; Humans; Lignans; Molecular Structure; Polycyclic Compounds; Quantitative Structure-Activity Relationship; Russia; Schisandra; Seeds

2014
A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Biotransformation; Catalysis; Cell Line; Cytochrome P-450 CYP3A; Humans; Isoenzymes; Kinetics; Limit of Detection; Molecular Probes

2017
Pharmacological actions and clinical use of fructus schizandrae.
    Chinese medical journal, 1989, Volume: 102, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Drugs, Chinese Herbal; Hepatitis B; Humans; Lignans; Lipid Peroxidation; Mice; Microsomes, Liver; Polycyclic Compounds; Rats

1989
Pharmacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism and mutagenicity.
    Chemico-biological interactions, 1982, Volume: 39, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; In Vitro Techniques; Lignans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Microsomes, Liver; Mutagens; NADP; Oxidation-Reduction; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Inbred Strains

1982
Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity.
    Journal of neuroscience research, 2004, May-01, Volume: 76, Issue:3

    Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Glutamic Acid; Intracellular Fluid; Lignans; Neurons; Neuroprotective Agents; Neurotoxins; Peroxides; Phytotherapy; Plant Extracts; Polycyclic Compounds; Rats; Schisandra

2004
[Study on the simultaneous spectrophotometric determination of three components including deoxyschizandrin by ridge regression method].
    Guang pu xue yu guang pu fen xi = Guang pu, 2004, Volume: 24, Issue:10

    Topics: Cyclooctanes; Lignans; Polycyclic Compounds; Regression Analysis; Spectrophotometry

2004
Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:6

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cyclooctanes; Dioxoles; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Fruit; Genes, MDR; Humans; Lignans; Mice; Mice, Nude; Neoplasm Proteins; Phytotherapy; Plant Preparations; Polycyclic Compounds; Protein Kinase C; Schisandra; Xenograft Model Antitumor Assays

2008
Optimization of extraction and purification of active fractions from Schisandra chinensis (Turcz.) and its osteoblastic proliferation stimulating activity.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:2

    Topics: Alkaline Phosphatase; Animals; Cell Line; Cell Proliferation; Chromatography, High Pressure Liquid; Cyclooctanes; Enzyme Activators; Lignans; Osteoblasts; Plant Extracts; Polycyclic Compounds; Rats; Schisandra

2009
[Lignans from different processed products of Schisandra chinensis fruits].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drug Compounding; Drugs, Chinese Herbal; Fruit; Hot Temperature; Lignans; Plants, Medicinal; Polycyclic Compounds; Quality Control; Schisandra; Spectrometry, Mass, Electrospray Ionization

2008
[Changes of lignans' content in stems of Schisandra chinensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:24

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Plant Stems; Polycyclic Compounds; Schisandra

2009
Study on ionic liquid-based ultrasonic-assisted extraction of biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill.
    Analytica chimica acta, 2011, Mar-09, Volume: 689, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Fruit; Ionic Liquids; Lignans; Plant Extracts; Polycyclic Compounds; Schisandra; Solid Phase Extraction; Time Factors; Ultrasonics

2011
Simultaneous and rapid determination of main lignans in different parts of Schisandra sphenanthera by micellar electrokinetic capillary chromatography.
    Molecules (Basel, Switzerland), 2011, May-03, Volume: 16, Issue:5

    Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclooctanes; Dioxoles; Lignans; Polycyclic Compounds

2011
Preparation of high purity biphenyl cyclooctene lignans from Schisandra extract by ion exchange resin catalytic transformation combined with macroporous resin separation.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-15, Volume: 879, Issue:30

    Topics: Adsorption; Analysis of Variance; Chromatography, Ion Exchange; Cyclooctanes; Dioxoles; Ethanol; Fruit; Hydrolysis; Ion Exchange Resins; Lignans; Plant Extracts; Polycyclic Compounds; Schisandra; Spectrometry, Mass, Electrospray Ionization; Temperature

2011
[Simultaneous quantitative analysis of four lignanoids in Schisandra chinensis by quantitative analysis of multi-components by single marker].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:7

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Fruit; Lignans; Plants, Medicinal; Polycyclic Compounds; Quality Control; Schisandra

2012
Pharmacokinetic study of schisandrin, schisandrol B, schisantherin A, deoxyschisandrin, and schisandrin B in rat plasma after oral administration of Shengmaisan formula by UPLC-MS.
    Journal of separation science, 2013, Volume: 36, Issue:3

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Male; Polycyclic Compounds; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization

2013
Effect of acupuncture on target tissue distribution of Schisandra lignans.
    Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2013, Volume: 31, Issue:2

    Topics: Acupuncture Therapy; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Polycyclic Compounds; Rats; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tandem Mass Spectrometry; Tissue Distribution

2013
Chemical-pharmacokinetic-pharmacodynamic fingerprints of Schisandra chinensis alcoholic extract.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:5

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Lignans; Male; Microsomes, Liver; Plants, Medicinal; Polycyclic Compounds; Random Allocation; Rats; Rats, Sprague-Dawley; Schisandra; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2013
Comparative pharmacokinetics and tissue distribution of schisandrin, deoxyschisandrin and schisandrin B in rats after combining acupuncture and herb medicine (schisandra chinensis).
    Biomedical chromatography : BMC, 2014, Volume: 28, Issue:8

    Topics: Acupuncture Therapy; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Linear Models; Plant Extracts; Polycyclic Compounds; Rats; Schisandra; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution

2014
[High performance preparation and structural confirmation of lignans from Schisandrae chinensis fructus by using HSCCC combined with ESI-MSn method].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:1

    Topics: Countercurrent Distribution; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Fruit; Lignans; Molecular Structure; Plants, Medicinal; Polycyclic Compounds; Schisandra; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
[Study on chemical constituents from Schisandra chinensis stem].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:10

    Topics: Cyclooctanes; Guaiacol; Lignans; Phytochemicals; Plant Stems; Polycyclic Compounds; Schisandra; Sitosterols

2014
Isolation of three dibenzocyclooctadiene lignans from in vitro cultures of Schisandra chinensis (Turcz.) Baill.--the first report.
    Die Pharmazie, 2015, Volume: 70, Issue:5

    Topics: Cells, Cultured; Chromatography, Thin Layer; Cyclooctanes; Dioxoles; Lignans; Magnetic Resonance Spectroscopy; Plant Leaves; Plant Shoots; Polycyclic Compounds; Schisandra

2015
Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:10

    Topics: Animals; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Glucuronosyltransferase; Herb-Drug Interactions; Lignans; Plant Extracts; Polycyclic Compounds; Rats; Schisandra; Structure-Activity Relationship

2015
Study on the pharmacokinetics of deoxyschizandrin and schizandrin in combination with epigallocatechin gallate, a component of green tea, in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:4

    Topics: Animals; Caco-2 Cells; Catechin; Cyclooctanes; Female; Humans; Lignans; Male; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Tea

2018
[Rapid identification of the different constituents in Fructus Schisandrae Chinensis before and after processing by UHPLC-QTOF/MS~E combining with metabonomics].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:9

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Fruit; Lignans; Metabolomics; Polycyclic Compounds; Schisandra

2016
[Analysis of lignans and their metabolites derived from Schisandra chinensis and vinegar Schisandra chinensis in rats’ plasma, bile, urine and faeces based on UHPLC-QTOF/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:10

    Topics: Acetic Acid; Animals; Bile; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Feces; Lignans; Liver Diseases, Alcoholic; Plasma; Polycyclic Compounds; Rats; Schisandra; Urine

2016
Chemical constituents isolated from stems of
    Natural product research, 2020, Volume: 34, Issue:18

    Topics: Animals; Cyclooctanes; Dioxoles; Feeding Behavior; Lignans; Plant Stems; Polycyclic Compounds; Schisandra; Sesquiterpenes; Structure-Activity Relationship; Tribolium; Triterpenes

2020
An integrated strategy for ascertaining quality marker of Schisandra chinensis (Turcz.) Baill based on correlation analysis between depression-related monoaminergic metabolites and chemical components profiling.
    Journal of chromatography. A, 2019, Aug-02, Volume: 1598

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lignans; Medicine, Chinese Traditional; Plants, Medicinal; Polycyclic Compounds; Quality Control; Rats; Schisandra; Tandem Mass Spectrometry

2019
A multidimensional strategy for uncovering comprehensive quality markers of Schisandra chinensis (Turcz.) Baill based on pharmacodynamics and chemical properties.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Biomarkers; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Polycyclic Compounds; Rats; Schisandra

2022