Page last updated: 2024-08-23

schizandrin a and schizandrin c

schizandrin a has been researched along with schizandrin c in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's1 (4.76)18.2507
2000's4 (19.05)29.6817
2010's13 (61.90)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Choi, YW; Ferreira, D; Khan, IA; Khan, SI; Srinivas, PV; Takamatsu, S; Zhao, J1
Bae, K; Chung, HJ; Hong, JY; Hung, TM; Kang, SS; Kang, YJ; Kim, SJ; Kim, YS; Lee, SK; Min, HY; Park, EJ; Woo, ER; Youn, UJ1
Adámková, L; Carnecká, M; Humpa, O; Páchniková, G; Porubová Koubíková, L; Slanina, J; Slaninová, I; Smejkal, K1
Cao, YF; Dou, TY; Feng, L; Ge, GB; Hao, DC; He, YQ; Hong, JY; Wang, P; Wu, JJ; Yang, L1
Liu, GT1
Lesca, P; Liu, KT1
Ko, KM; Yim, TK1
Kim, SH; Kim, SR; Kim, YC; Koo, KA; Lee, MK; Lee, NG; Markelonis, GJ; Oh, TH; Sung, SH; Yang, JH1
Huang, M; Jin, J; Liu, GT; Sun, H1
Guan, M; Li, T; Liu, Y; Sheng, Y; Wang, Y; Yuan, G1
Bi, HC; Chen, X; Huang, M; Li, JL; Qin, XL; Wang, CX; Wang, XD; Wang, Y; Xue, XP; Yang, H; Zhong, GP1
Bi, H; Chen, P; Fan, X; Huang, M; Jiang, Y; Tan, H; Wang, Y; Zeng, H1
Liu, CH; Liu, S; Tao, YY; Yang, T; Zheng, TH1
Cai, Q; Du, SS; Zheng, LS1
An, LB; Cui, L; Dong, PP; Fang, ZZ; Gonzalez, FJ; Li, WT; Song, JH; Sun, XY; Wang, LX; Wu, X; Zhang, YY; Zhao, DW1
An, F; Guo, M; Hong, M; Lu, Y; Wei, X1
An, F; Guo, M; Hong, M; Lu, Y; Wei, X; Yu, H1
Feng, YL; Li, W; Liu, KY; Liu, YL; Song, YG; Su, D; Yang, LJ1
Cheng, X; Ding, XY; Ji, JD; Lu, TL; Mao, CQ; Su, LL; Wang, LJ; Zhang, J1
Bi, K; Gao, H; Li, Q; Liu, H; Liu, R; Lv, X; Xu, H; Zhang, M; Zhang, Q; Zhang, Y1
Bi, K; Li, Q; Li, S; Xu, H; Yang, P; Zhang, Q; Zhang, Y1

Other Studies

21 other study(ies) available for schizandrin a and schizandrin c

ArticleYear
Schisandrene, a dibenzocyclooctadiene lignan from Schisandra chinensis: structure-antioxidant activity relationships of dibenzocyclooctadiene lignans.
    Journal of natural products, 2006, Volume: 69, Issue:3

    Topics: Antioxidants; Cyclooctanes; Korea; Lignans; Molecular Structure; Plants, Medicinal; Schisandra; Structure-Activity Relationship

2006
Antiproliferative effects of dibenzocyclooctadiene lignans isolated from Schisandra chinensis in human cancer cells.
    Bioorganic & medicinal chemistry letters, 2008, Jan-15, Volume: 18, Issue:2

    Topics: Cell Line, Tumor; Cell Proliferation; Cyclooctanes; Humans; Lignans; Molecular Structure; Schisandra

2008
Identification of key structural characteristics of Schisandra chinensis lignans involved in P-glycoprotein inhibition.
    Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cyclooctanes; Doxorubicin; G2 Phase Cell Cycle Checkpoints; Humans; Lignans; Molecular Structure; Polycyclic Compounds; Quantitative Structure-Activity Relationship; Russia; Schisandra; Seeds

2014
A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Biotransformation; Catalysis; Cell Line; Cytochrome P-450 CYP3A; Humans; Isoenzymes; Kinetics; Limit of Detection; Molecular Probes

2017
Pharmacological actions and clinical use of fructus schizandrae.
    Chinese medical journal, 1989, Volume: 102, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Drugs, Chinese Herbal; Hepatitis B; Humans; Lignans; Lipid Peroxidation; Mice; Microsomes, Liver; Polycyclic Compounds; Rats

1989
Pharmacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism and mutagenicity.
    Chemico-biological interactions, 1982, Volume: 39, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; In Vitro Techniques; Lignans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Microsomes, Liver; Mutagens; NADP; Oxidation-Reduction; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Inbred Strains

1982
Methylenedioxy group and cyclooctadiene ring as structural determinants of schisandrin in protecting against myocardial ischemia-reperfusion injury in rats.
    Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

    Topics: Animals; Antioxidants; Cyclooctanes; Drugs, Chinese Herbal; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Lignans; Male; Molecular Conformation; Molecular Structure; Myocardial Reperfusion Injury; Myocardium; Polycyclic Compounds; Rats; Rats, Sprague-Dawley

1999
Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity.
    Journal of neuroscience research, 2004, May-01, Volume: 76, Issue:3

    Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Glutamic Acid; Intracellular Fluid; Lignans; Neurons; Neuroprotective Agents; Neurotoxins; Peroxides; Phytotherapy; Plant Extracts; Polycyclic Compounds; Rats; Schisandra

2004
Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:6

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cyclooctanes; Dioxoles; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Fruit; Genes, MDR; Humans; Lignans; Mice; Mice, Nude; Neoplasm Proteins; Phytotherapy; Plant Preparations; Polycyclic Compounds; Protein Kinase C; Schisandra; Xenograft Model Antitumor Assays

2008
Simultaneous and rapid determination of main lignans in different parts of Schisandra sphenanthera by micellar electrokinetic capillary chromatography.
    Molecules (Basel, Switzerland), 2011, May-03, Volume: 16, Issue:5

    Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclooctanes; Dioxoles; Lignans; Polycyclic Compounds

2011
In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) on the CYP3A/P-glycoprotein-mediated absorption and metabolism of tacrolimus.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:1

    Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Drugs, Chinese Herbal; Humans; Lignans; Male; Microsomes, Liver; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Tablets; Tacrolimus

2014
Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
    Chemico-biological interactions, 2015, Apr-25, Volume: 231

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dioxoles; Lignans; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Polycyclic Compounds; Protective Agents; Schisandra

2015
Comparative pharmacokinetics and tissue distribution profiles of lignan components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe.
    Journal of ethnopharmacology, 2015, May-26, Volume: 166

    Topics: Administration, Oral; Animals; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Kidney; Lignans; Liver; Liver Cirrhosis; Male; Polycyclic Compounds; Rats; Rats, Wistar; Tissue Distribution

2015
[Study on chemical constituents from Schisandra chinensis stem].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:10

    Topics: Cyclooctanes; Guaiacol; Lignans; Phytochemicals; Plant Stems; Polycyclic Compounds; Schisandra; Sitosterols

2014
Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:10

    Topics: Animals; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Glucuronosyltransferase; Herb-Drug Interactions; Lignans; Plant Extracts; Polycyclic Compounds; Rats; Schisandra; Structure-Activity Relationship

2015
Comparative Effects of Schisandrin A, B, and C on Acne-Related Inflammation.
    Inflammation, 2017, Volume: 40, Issue:6

    Topics: Acne Vulgaris; Anti-Inflammatory Agents; Cyclooctanes; Humans; Inflammation; Lignans; MAP Kinase Signaling System; Polycyclic Compounds; Propionibacterium acnes; THP-1 Cells

2017
Comparative effects of schisandrin A, B, and C on Propionibacterium acnes-induced, NLRP3 inflammasome activation-mediated IL-1β secretion and pyroptosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Cell Survival; Cyclooctanes; Humans; Interleukin-1beta; Lignans; NLR Family, Pyrin Domain-Containing 3 Protein; Polycyclic Compounds; Propionibacterium acnes; Pyroptosis; Schisandra; THP-1 Cells

2017
[Rapid identification of the different constituents in Fructus Schisandrae Chinensis before and after processing by UHPLC-QTOF/MS~E combining with metabonomics].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:9

    Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Fruit; Lignans; Metabolomics; Polycyclic Compounds; Schisandra

2016
[Analysis of lignans and their metabolites derived from Schisandra chinensis and vinegar Schisandra chinensis in rats’ plasma, bile, urine and faeces based on UHPLC-QTOF/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:10

    Topics: Acetic Acid; Animals; Bile; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Feces; Lignans; Liver Diseases, Alcoholic; Plasma; Polycyclic Compounds; Rats; Schisandra; Urine

2016
An integrated strategy for ascertaining quality marker of Schisandra chinensis (Turcz.) Baill based on correlation analysis between depression-related monoaminergic metabolites and chemical components profiling.
    Journal of chromatography. A, 2019, Aug-02, Volume: 1598

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lignans; Medicine, Chinese Traditional; Plants, Medicinal; Polycyclic Compounds; Quality Control; Rats; Schisandra; Tandem Mass Spectrometry

2019
A multidimensional strategy for uncovering comprehensive quality markers of Schisandra chinensis (Turcz.) Baill based on pharmacodynamics and chemical properties.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Biomarkers; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Polycyclic Compounds; Rats; Schisandra

2022