schizandrin a has been researched along with schizandrin b in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.33) | 18.7374 |
| 1990's | 2 (3.33) | 18.2507 |
| 2000's | 15 (25.00) | 29.6817 |
| 2010's | 39 (65.00) | 24.3611 |
| 2020's | 2 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, X; Li, L; Lu, Q; Pan, Q; Sun, M | 1 |
| Adámková, L; Carnecká, M; Humpa, O; Páchniková, G; Porubová Koubíková, L; Slanina, J; Slaninová, I; Smejkal, K | 1 |
| Hu, M; Li, J; Ma, X; Wang, H | 1 |
| Liu, GT | 1 |
| Lesca, P; Liu, KT | 1 |
| Che, CT; Ip, SP; Ko, KM; Ma, CY | 1 |
| Ko, KM; Yim, TK | 1 |
| Yang, SB | 1 |
| Kim, SH; Kim, SR; Kim, YC; Koo, KA; Lee, MK; Lee, NG; Markelonis, GJ; Oh, TH; Sung, SH; Yang, JH | 1 |
| Burgos, RA; Folch, H; Hancke, JL; Hermosilla, R; Hidalgo, MA; Matthei, SM | 1 |
| Li, JQ; Li, P; Mu, J; Zhang, LQ; Zhu, XL | 1 |
| Huang, T; Shen, P; Shen, Y | 1 |
| Anjia, C; Cunhong, L; Wenhua, G; Xingguo, C; Zhide, H | 1 |
| Hu, X; Lu, Q; Pan, Q; Zhang, K | 1 |
| Huang, M; Jin, J; Liu, GT; Sun, H | 1 |
| Caichompoo, W; Gao, HJ; Hou, TT; Qin, LP; Zhang, QY; Zhou, XJ | 1 |
| Huang, X; Liu, SY; Liu, ZQ; Song, FR | 1 |
| Liu, C; Wu, H; Zhang, S | 1 |
| Gao, Q; Li, X; Luo, H; Weng, W; Xiao, F | 1 |
| Hu, Y; Sun, R; Yu, J; Zhou, J | 1 |
| Li, WL; Su, MW; Xin, HW; Xiong, L | 1 |
| Cai, BC; Chen, XM; Di, LQ; Han, L; Li, JS; Li, W; Liu, XH | 1 |
| Chen, Q; Cheng, NN; Li, YL; Wang, YM; Wu, YJ | 1 |
| Guan, M; Li, T; Liu, Y; Sheng, Y; Wang, Y; Yuan, G | 1 |
| Ma, CH; Yang, FJ; Yang, L; Zhang, Y; Zhao, CJ; Zu, YG | 1 |
| Dong, JP; He, FC; Li, SX; Liu, WZ; Su, RQ; Zhao, ZQ | 1 |
| Han, Y; Sun, H; Wang, X; Wei, W; Wu, F; Zhang, A | 1 |
| Chen, H; Huang, ZJ; Lu, TL; Mao, CQ; Song, Y; Sun, Y; Wu, XY; Xu, B; Zhou, Y | 1 |
| Ekiert, H; Szopa, A | 1 |
| Chen, H; Hu, JP; Li, Y; Sheng, L; Wang, BL | 1 |
| Bi, HC; Chen, X; Huang, M; Li, JL; Qin, XL; Wang, CX; Wang, XD; Wang, Y; Xue, XP; Yang, H; Zhong, GP | 1 |
| Dai, G; Ji, D; Li, L; Lu, T; Mao, C; Sun, Y; Wu, X; Xu, B; Yin, F; Zhou, Y | 1 |
| Han, L; Qu, J; Qu, Q; Wu, LX; Zhan, M; Zhang, W; Zhang, YW; Zhou, HH | 1 |
| Cai, H; Che, GY; Cong, YL; Jin, B; Li, ZY; Liu, Y; Si, L; Sun, YX; Tang, B; Wang, AB; Wang, CF; Zhang, XM | 1 |
| Carrara, M; Casarin, E; Dall'Acqua, S; Innocenti, G; Slapetová, T; Smejkal, K | 1 |
| Cheng, Q; Ji, B; Liu, J; Wang, O; Wang, Y; Zhao, L; Zhou, F | 1 |
| Corona, A; Del Vecchio, C; Esposito, F; Grandi, N; Mandas, D; Parolin, C; Piano, D; Tramontano, E; Xu, L | 1 |
| Bi, H; Chen, P; Fan, X; Huang, M; Jiang, Y; Tan, H; Wang, Y; Zeng, H | 1 |
| Liu, CH; Liu, S; Tao, YY; Yang, T; Zheng, TH | 1 |
| Cai, Q; Du, SS; Zheng, LS | 1 |
| Elofsson, M; Hakala, E; Hanski, L; Uvell, H; Vuorela, H; Vuorela, PM; Yrjönen, T | 1 |
| Deng, S; Guo, CX; Liu, ZQ; Yin, JY; Zhang, W; Zhou, HH | 1 |
| Gao, W; Hou, W; Liu, Q; Wang, D; Wang, Y; Zheng, S | 1 |
| Chan, WM; Chen, J; Ko, KM; Leong, PK; Leung, HY; Wong, HS | 1 |
| Bradbury, EJ; Brown, CF; Lyles, JT; Nelson, K; Pierce, ST; Quave, CL; Tyler, P | 1 |
| Geng, Y; Guo, F; Li, S; Wang, S; Wei, J; Wu, H; Yang, H; Yu, Y; Zhang, M | 1 |
| An, F; Guo, M; Hong, M; Lu, Y; Wei, X | 1 |
| An, F; Guo, M; Hong, M; Lu, Y; Wei, X; Yu, H | 1 |
| Chen, L; Hu, Q; Huang, S; Lu, Y; Xia, C; Xiong, Y; Zhang, H | 1 |
| Feng, YL; Li, W; Liu, KY; Liu, YL; Song, YG; Su, D; Yang, LJ | 1 |
| Cheng, X; Ding, XY; Ji, JD; Lu, TL; Mao, CQ; Su, LL; Wang, LJ; Zhang, J | 1 |
| Du, Z; Fu, Q; Hu, CM; Hu, RX; Yang, K; Zhang, X | 1 |
| Chen, AC; Chen, WC; Lu, CK; Ueng, YF; Wang, HJ | 1 |
| Bi, K; Gao, H; Li, Q; Liu, H; Liu, R; Lv, X; Xu, H; Zhang, M; Zhang, Q; Zhang, Y | 1 |
| Cai, NN; Jiang, Y; Wang, ZZ; Yang, R; Zhang, XM; Zhu, WQ; Zhu, XC | 1 |
| Bi, K; Li, Q; Li, S; Xu, H; Yang, P; Zhang, Q; Zhang, Y | 1 |
| Choi, YW; Ferreira, D; Khan, IA; Khan, SI; Srinivas, PV; Takamatsu, S; Zhao, J | 1 |
| Bae, K; Chung, HJ; Hong, JY; Hung, TM; Kang, SS; Kang, YJ; Kim, SJ; Kim, YS; Lee, SK; Min, HY; Park, EJ; Woo, ER; Youn, UJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Cao, YF; Dou, TY; Feng, L; Ge, GB; Hao, DC; He, YQ; Hong, JY; Wang, P; Wu, JJ; Yang, L | 1 |
1 review(s) available for schizandrin a and schizandrin b
| Article | Year |
|---|---|
Discovery of traditional Chinese medicine monomers and their synthetic intermediates, analogs or derivatives for battling P-gp-mediated multi-drug resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Discovery; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional | 2018 |
59 other study(ies) available for schizandrin a and schizandrin b
| Article | Year |
|---|---|
Dibenzocyclooctadiene lignans: a class of novel inhibitors of multidrug resistance-associated protein 1.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cyclooctanes; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Lignans; Multidrug Resistance-Associated Proteins | 2007 |
Identification of key structural characteristics of Schisandra chinensis lignans involved in P-glycoprotein inhibition.
Topics: ATP Binding Cassette Transporter, Subfamily B; Cyclooctanes; Doxorubicin; G2 Phase Cell Cycle Checkpoints; Humans; Lignans; Molecular Structure; Polycyclic Compounds; Quantitative Structure-Activity Relationship; Russia; Schisandra; Seeds | 2014 |
Pharmacological actions and clinical use of fructus schizandrae.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; Drugs, Chinese Herbal; Hepatitis B; Humans; Lignans; Lipid Peroxidation; Mice; Microsomes, Liver; Polycyclic Compounds; Rats | 1989 |
Pharmacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism and mutagenicity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; In Vitro Techniques; Lignans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Microsomes, Liver; Mutagens; NADP; Oxidation-Reduction; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1982 |
Methylenedioxy group as determinant of schisandrin in enhancing hepatic mitochondrial glutathione in carbon tetrachloride-intoxicated mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Drugs, Chinese Herbal; Female; Glutathione; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Polycyclic Compounds; Structure-Activity Relationship | 1997 |
Methylenedioxy group and cyclooctadiene ring as structural determinants of schisandrin in protecting against myocardial ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Cyclooctanes; Drugs, Chinese Herbal; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Lignans; Male; Molecular Conformation; Molecular Structure; Myocardial Reperfusion Injury; Myocardium; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 1999 |
[Study on supercritical CO2 fluid extraction and separation of components from fruits of Schisandra sphenanthera].
Topics: Carbon Dioxide; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Cyclooctanes; Fruit; Lignans; Plants, Medicinal; Polycyclic Compounds; Schisandra | 2001 |
Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Glutamic Acid; Intracellular Fluid; Lignans; Neurons; Neuroprotective Agents; Neurotoxins; Peroxides; Phytotherapy; Plant Extracts; Polycyclic Compounds; Rats; Schisandra | 2004 |
Determination of specific receptor sites for platelet activating factor in bovine neutrophils.
Topics: Animals; Azepines; Base Sequence; Blotting, Western; Cattle; Cyclooctanes; Diterpenes; DNA Primers; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Ginkgolides; HL-60 Cells; Humans; Kinetics; Lactones; Lignans; Molecular Sequence Data; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polycyclic Compounds; Radioligand Assay; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Triazoles; Tritium | 2004 |
[Study on the simultaneous spectrophotometric determination of three components including deoxyschizandrin by ridge regression method].
Topics: Cyclooctanes; Lignans; Polycyclic Compounds; Regression Analysis; Spectrophotometry | 2004 |
Preparative separation and purification of deoxyschisandrin and gamma-schisandrin from Schisandra chinensis (Turcz.) Baill by high-speed counter-current chromatography.
Topics: Chromatography, High Pressure Liquid; Countercurrent Distribution; Cyclooctanes; Fruit; Lignans; Polycyclic Compounds; Schisandra; Solvents | 2005 |
Separation and determination of active components in Schisandra chinensis Baill. and its medicinal preparations by non-aqueous capillary electrophoresis.
Topics: Cyclooctanes; Drugs, Chinese Herbal; Electrophoresis, Capillary; Lignans; Polycyclic Compounds; Reproducibility of Results; Schisandra; Seeds; Temperature | 2005 |
Dibenzocyclooctadiene lingnans: a class of novel inhibitors of P-glycoprotein.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cyclooctanes; Daunorubicin; Dioxoles; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; K562 Cells; Lignans; Paclitaxel; Polycyclic Compounds; Prohibitins; Vincristine | 2006 |
Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cyclooctanes; Dioxoles; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Fruit; Genes, MDR; Humans; Lignans; Mice; Mice, Nude; Neoplasm Proteins; Phytotherapy; Plant Preparations; Polycyclic Compounds; Protein Kinase C; Schisandra; Xenograft Model Antitumor Assays | 2008 |
Optimization of extraction and purification of active fractions from Schisandra chinensis (Turcz.) and its osteoblastic proliferation stimulating activity.
Topics: Alkaline Phosphatase; Animals; Cell Line; Cell Proliferation; Chromatography, High Pressure Liquid; Cyclooctanes; Enzyme Activators; Lignans; Osteoblasts; Plant Extracts; Polycyclic Compounds; Rats; Schisandra | 2009 |
[Lignans from different processed products of Schisandra chinensis fruits].
Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drug Compounding; Drugs, Chinese Herbal; Fruit; Hot Temperature; Lignans; Plants, Medicinal; Polycyclic Compounds; Quality Control; Schisandra; Spectrometry, Mass, Electrospray Ionization | 2008 |
Non-thermal extraction of effective ingredients from Schisandra chinensis Baill and the antioxidant activity of its extract.
Topics: Antioxidants; Chemical Fractionation; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Lignans; Plant Extracts; Polycyclic Compounds; Pressure; Schisandra | 2009 |
[Research on liposoluble ingredients of Quchiling].
Topics: Allylbenzene Derivatives; Animals; Anisoles; Brain; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Female; Gas Chromatography-Mass Spectrometry; Lignans; Male; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 2010 |
[Changes of lignans' content in stems of Schisandra chinensis].
Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Plant Stems; Polycyclic Compounds; Schisandra | 2009 |
Inhibitory effects of schisandrin A and schisandrin B on CYP3A activity.
Topics: Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inhibitory Concentration 50; Lignans; Male; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Wistar; Time Factors | 2010 |
[Intestinal absorption of the effective components of Schisandra chinensis Baill by rats single-pass perfusion in situ].
Topics: Animals; Chromatography, High Pressure Liquid; Colon; Cyclooctanes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Duodenum; Fruit; Ileum; Intestinal Absorption; Jejunum; Lignans; Male; Perfusion; Permeability; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Schisandra | 2010 |
[Dual effects of extract of Schisandra chinensis Baill on rat hepatic CYP3A].
Topics: Animals; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hepatocytes; Inhibitory Concentration 50; Lignans; Male; Microsomes, Liver; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Schisandra | 2010 |
Simultaneous and rapid determination of main lignans in different parts of Schisandra sphenanthera by micellar electrokinetic capillary chromatography.
Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclooctanes; Dioxoles; Lignans; Polycyclic Compounds | 2011 |
Enrichment and purification of deoxyschizandrin and γ-schizandrin from the extract of Schisandra chinensis fruit by macroporous resins.
Topics: Adsorption; Cyclooctanes; Fruit; Lignans; Polycyclic Compounds; Resins, Synthetic; Schisandra | 2012 |
[Simultaneous quantitative analysis of four lignanoids in Schisandra chinensis by quantitative analysis of multi-components by single marker].
Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Fruit; Lignans; Plants, Medicinal; Polycyclic Compounds; Quality Control; Schisandra | 2012 |
Pharmacokinetic study of schisandrin, schisandrol B, schisantherin A, deoxyschisandrin, and schisandrin B in rat plasma after oral administration of Shengmaisan formula by UPLC-MS.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Male; Polycyclic Compounds; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization | 2013 |
Effect of acupuncture on target tissue distribution of Schisandra lignans.
Topics: Acupuncture Therapy; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Polycyclic Compounds; Rats; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tandem Mass Spectrometry; Tissue Distribution | 2013 |
Production of deoxyschizandrin and γ-schizandrin in shoot-differentiating and undifferentiating callus cultures of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine).
Topics: Cell Differentiation; Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Methanol; Plant Shoots; Polycyclic Compounds; Schisandra; Sonication | 2013 |
Chemical-pharmacokinetic-pharmacodynamic fingerprints of Schisandra chinensis alcoholic extract.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Lignans; Male; Microsomes, Liver; Plants, Medicinal; Polycyclic Compounds; Random Allocation; Rats; Rats, Sprague-Dawley; Schisandra; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2013 |
In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) on the CYP3A/P-glycoprotein-mediated absorption and metabolism of tacrolimus.
Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Drugs, Chinese Herbal; Humans; Lignans; Male; Microsomes, Liver; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Tablets; Tacrolimus | 2014 |
Comparative pharmacokinetics and tissue distribution of schisandrin, deoxyschisandrin and schisandrin B in rats after combining acupuncture and herb medicine (schisandra chinensis).
Topics: Acupuncture Therapy; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cyclooctanes; Lignans; Linear Models; Plant Extracts; Polycyclic Compounds; Rats; Schisandra; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution | 2014 |
Inhibitory effects of phytochemicals on metabolic capabilities of CYP2D6(*)1 and CYP2D6(*)10 using cell-based models in vitro.
Topics: Berberine; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coumarins; Cyclooctanes; Cyclopentanes; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Furans; Ginkgolides; Hep G2 Cells; Humans; Isoflavones; Kinetics; Lignans; Luteolin; Phytochemicals; Polycyclic Compounds | 2014 |
Schisandrin A and B affect subventricular zone neurogenesis in mouse.
Topics: Animals; Cell Proliferation; Cell Survival; Cyclooctanes; Lateral Ventricles; Lignans; Male; Mice; Neurogenesis; Neurons; Olfactory Bulb; Polycyclic Compounds | 2014 |
Molecular mechanisms of antiproliferative effects induced by Schisandra-derived dibenzocyclooctadiene lignans (+)-deoxyschisandrin and (-)-gomisin N in human tumour cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclooctanes; Fruit; Humans; Lignans; Molecular Structure; Polycyclic Compounds; Schisandra | 2014 |
Hepatoprotective effect of Schisandra chinensis (Turcz.) Baill. lignans and its formula with Rubus idaeus on chronic alcohol-induced liver injury in mice.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Lignans; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred ICR; Plant Extracts; Polycyclic Compounds; Rubus; Schisandra | 2014 |
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Cyclooctanes; Drug Resistance, Multiple, Viral; Drugs, Chinese Herbal; Fruit; HIV Reverse Transcriptase; HIV-1; Lignans; Mutation; Polycyclic Compounds; Reverse Transcriptase Inhibitors; Schisandra; Virus Replication | 2015 |
Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dioxoles; Lignans; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Polycyclic Compounds; Protective Agents; Schisandra | 2015 |
Comparative pharmacokinetics and tissue distribution profiles of lignan components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe.
Topics: Administration, Oral; Animals; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Kidney; Lignans; Liver; Liver Cirrhosis; Male; Polycyclic Compounds; Rats; Rats, Wistar; Tissue Distribution | 2015 |
[Study on chemical constituents from Schisandra chinensis stem].
Topics: Cyclooctanes; Guaiacol; Lignans; Phytochemicals; Plant Stems; Polycyclic Compounds; Schisandra; Sitosterols | 2014 |
Dibenzocyclooctadiene lignans from Schisandra spp. selectively inhibit the growth of the intracellular bacteria Chlamydia pneumoniae and Chlamydia trachomatis.
Topics: Anti-Bacterial Agents; Bacteria; Cell Line; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Cyclooctanes; Humans; Lignans; Microbial Sensitivity Tests; Polycyclic Compounds; Reactive Oxygen Species; Schisandra | 2015 |
Schisandrin A and B induce organic anion transporting polypeptide 1B1 transporter activity.
Topics: Abietanes; Cell Line, Tumor; Cyclooctanes; Estrone; Humans; Lignans; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Plants, Medicinal; Polycyclic Compounds; RNA, Messenger | 2015 |
The Protecting Effect of Deoxyschisandrin and Schisandrin B on HaCaT Cells against UVB-Induced Damage.
Topics: Antioxidants; Apoptosis; Caspases; Cell Line; Cell Survival; Cyclooctanes; Cytoprotection; DNA Damage; Humans; Keratinocytes; Lignans; Polycyclic Compounds; Reactive Oxygen Species; Schisandra; Ultraviolet Rays | 2015 |
Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Concanavalin A; Cyclooctanes; Cytokines; Edema; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Glutathione Transferase; Inflammation; Lignans; Lipopolysaccharides; Mice; Mice, Inbred ICR; Polycyclic Compounds; RAW 264.7 Cells | 2016 |
Comparative Phytochemical Analysis of Chinese and Bay Starvine (Schisandra spp.): Potential for Development as a New Dietary Supplement Ingredient.
Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dietary Supplements; Dioxoles; Fruit; Lignans; Medicine, Chinese Traditional; Phenols; Phytochemicals; Plant Extracts; Polycyclic Compounds; Schisandra; Spectroscopy, Fourier Transform Infrared; Tannins | 2017 |
Identification of active components in Yixinshu Capsule with protective effects against myocardial dysfunction on human induced pluripotent stem cell-derived cardiomyocytes by an integrative approach.
Topics: Actinin; Animals; Bosentan; Cardiotonic Agents; Cell Differentiation; Cell Line; Cyclooctanes; Drugs, Chinese Herbal; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Humans; Induced Pluripotent Stem Cells; Intestinal Mucosa; Intestines; Lignans; Male; Medicine, Chinese Traditional; Metabolic Networks and Pathways; Metabolome; Myocytes, Cardiac; Natriuretic Peptide, Brain; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Sulfonamides; Troponin T | 2017 |
Comparative Effects of Schisandrin A, B, and C on Acne-Related Inflammation.
Topics: Acne Vulgaris; Anti-Inflammatory Agents; Cyclooctanes; Humans; Inflammation; Lignans; MAP Kinase Signaling System; Polycyclic Compounds; Propionibacterium acnes; THP-1 Cells | 2017 |
Comparative effects of schisandrin A, B, and C on Propionibacterium acnes-induced, NLRP3 inflammasome activation-mediated IL-1β secretion and pyroptosis.
Topics: Cell Survival; Cyclooctanes; Humans; Interleukin-1beta; Lignans; NLR Family, Pyrin Domain-Containing 3 Protein; Polycyclic Compounds; Propionibacterium acnes; Pyroptosis; Schisandra; THP-1 Cells | 2017 |
Interaction of deoxyschizandrin and schizandrin B with liver uptake transporters OATP1B1 and OATP1B3.
Topics: Atorvastatin; Cyclooctanes; Drug Interactions; HEK293 Cells; Humans; Kinetics; Lignans; Liver; Liver-Specific Organic Anion Transporter 1; Polycyclic Compounds; Protective Agents; Rosuvastatin Calcium; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2019 |
[Rapid identification of the different constituents in Fructus Schisandrae Chinensis before and after processing by UHPLC-QTOF/MS~E combining with metabonomics].
Topics: Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Fruit; Lignans; Metabolomics; Polycyclic Compounds; Schisandra | 2016 |
[Analysis of lignans and their metabolites derived from Schisandra chinensis and vinegar Schisandra chinensis in rats’ plasma, bile, urine and faeces based on UHPLC-QTOF/MS].
Topics: Acetic Acid; Animals; Bile; Chromatography, High Pressure Liquid; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Feces; Lignans; Liver Diseases, Alcoholic; Plasma; Polycyclic Compounds; Rats; Schisandra; Urine | 2016 |
Evaluation of the inhibition of human carboxylesterases (CESs) by the active ingredients from
Topics: Carboxylesterase; Carboxylic Ester Hydrolases; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Humans; Lignans; Microsomes, Liver; Molecular Docking Simulation; Polycyclic Compounds; Schisandra | 2019 |
Shenmai-Yin decreased the clearance of nifedipine in rats: The involvement of time-dependent inhibition of nifedipine oxidation.
Topics: Animals; Cyclooctanes; Cytochrome P-450 CYP3A; Drug Interactions; Drugs, Chinese Herbal; Humans; Lignans; Male; Nifedipine; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 2019 |
An integrated strategy for ascertaining quality marker of Schisandra chinensis (Turcz.) Baill based on correlation analysis between depression-related monoaminergic metabolites and chemical components profiling.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Cyclooctanes; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lignans; Medicine, Chinese Traditional; Plants, Medicinal; Polycyclic Compounds; Quality Control; Rats; Schisandra; Tandem Mass Spectrometry | 2019 |
Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus.
Topics: Animals; Cell Proliferation; Cyclooctanes; Dentate Gyrus; Hippocampus; Lignans; Male; Mice; Neurogenesis; Neurons; Polycyclic Compounds | 2020 |
A multidimensional strategy for uncovering comprehensive quality markers of Schisandra chinensis (Turcz.) Baill based on pharmacodynamics and chemical properties.
Topics: Animals; Biomarkers; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Lignans; Polycyclic Compounds; Rats; Schisandra | 2022 |
Schisandrene, a dibenzocyclooctadiene lignan from Schisandra chinensis: structure-antioxidant activity relationships of dibenzocyclooctadiene lignans.
Topics: Antioxidants; Cyclooctanes; Korea; Lignans; Molecular Structure; Plants, Medicinal; Schisandra; Structure-Activity Relationship | 2006 |
Antiproliferative effects of dibenzocyclooctadiene lignans isolated from Schisandra chinensis in human cancer cells.
Topics: Cell Line, Tumor; Cell Proliferation; Cyclooctanes; Humans; Lignans; Molecular Structure; Schisandra | 2008 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5.
Topics: Biotransformation; Catalysis; Cell Line; Cytochrome P-450 CYP3A; Humans; Isoenzymes; Kinetics; Limit of Detection; Molecular Probes | 2017 |