schizandrer a has been researched along with tacrolimus in 2 studies
| Studies (schizandrer a) | Trials (schizandrer a) | Recent Studies (post-2010) (schizandrer a) | Studies (tacrolimus) | Trials (tacrolimus) | Recent Studies (post-2010) (tacrolimus) |
|---|---|---|---|---|---|
| 65 | 0 | 52 | 17,757 | 2,319 | 6,661 |
| Protein | Taxonomy | schizandrer a (IC50) | tacrolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 7.18 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.58 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.385 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0021 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.2547 | |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | 0.0148 | |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | 0.0123 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bi, HC; Chen, X; Huang, M; Li, JL; Qin, XL; Wang, CX; Wang, XD; Wang, Y; Xue, XP; Yang, H; Zhong, GP | 1 |
| Bu, F; Cai, W; Jiao, Z; Li, L; Lin, HS; Ma, G; Shin, JG; Xiang, X; Zhang, H; Zhuang, X | 1 |
2 other study(ies) available for schizandrer a and tacrolimus
| Article | Year |
|---|---|
In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) on the CYP3A/P-glycoprotein-mediated absorption and metabolism of tacrolimus.
Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Drugs, Chinese Herbal; Humans; Lignans; Male; Microsomes, Liver; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Tablets; Tacrolimus | 2014 |
Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling.
Topics: Area Under Curve; Biotransformation; China; Computational Biology; Computer Simulation; Cyclooctanes; Cytochrome P-450 CYP3A Inhibitors; Dioxoles; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Expert Systems; Female; Humans; Immunosuppressive Agents; Lignans; Male; Models, Biological; Polycyclic Compounds; Protective Agents; Software; Tacrolimus | 2018 |