Compounds > sch 58261
Page last updated: 2024-09-05

sch 58261 and phenylisopropyladenosine

sch 58261 has been researched along with phenylisopropyladenosine in 4 studies

Compound Research Comparison

Studies
(sch 58261)		Trials
(sch 58261)		Recent Studies (post-2010)
(sch 58261)		Studies
(phenylisopropyladenosine)		Trials
(phenylisopropyladenosine)		Recent Studies (post-2010) (phenylisopropyladenosine)
4601463010

Protein Interaction Comparison

ProteinTaxonomysch 58261 (IC50)phenylisopropyladenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)1.8613
Adenosine receptor A1Rattus norvegicus (Norway rat)0.0294
Adenosine receptor A3Rattus norvegicus (Norway rat)0.0497
Adenosine receptor A2bRattus norvegicus (Norway rat)0.2898
Adenosine receptor A1Homo sapiens (human)0.83
Adenosine receptor A2aRattus norvegicus (Norway rat)0.2898

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schofield, PR; Townsend-Nicholson, A1
Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C1
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U1
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW1

Other Studies

4 other study(ies) available for sch 58261 and phenylisopropyladenosine

ArticleYear
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Humans; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Radioligand Assay; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Theophylline; Threonine; Tritium

1994
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
    British journal of pharmacology, 1997, Volume: 121, Issue:3

    Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles

1997
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
    Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium

1999
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
    Molecular pharmacology, 2000, Volume: 58, Issue:6

    Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine

2000