sch 58261 has been researched along with adenosine-5'-(n-ethylcarboxamide) in 8 studies
| Studies (sch 58261) | Trials (sch 58261) | Recent Studies (post-2010) (sch 58261) | Studies (adenosine-5'-(n-ethylcarboxamide)) | Trials (adenosine-5'-(n-ethylcarboxamide)) | Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide)) |
|---|---|---|---|---|---|
| 46 | 0 | 14 | 1,333 | 4 | 133 |
| Protein | Taxonomy | sch 58261 (IC50) | adenosine-5'-(n-ethylcarboxamide) (IC50) |
|---|---|---|---|
| Adenosine receptor A3 | Homo sapiens (human) | 0.0097 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.4498 | |
| Adenosine receptor A2a | Homo sapiens (human) | 0.0336 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 0.0175 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0007 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0513 | |
| Adenosine receptor A1 | Gallus gallus (chicken) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schofield, PR; Townsend-Nicholson, A | 1 |
| Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C | 1 |
| Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U | 1 |
| Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW | 1 |
| Beukers, MW; Brussee, J; de Graaf, O; de Vries, H; Göblyös, A; Ijzerman, AP; Link, R; Mantri, M; Mulder-Krieger, T; van Veldhoven, J; von Frijtag Drabbe Künzel, JK | 1 |
| Barodia, SK; Luthra, PM; Mishra, CB; Prakash, A; Senthil Kumar, JB | 1 |
| Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L | 1 |
| de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
2 review(s) available for sch 58261 and adenosine-5'-(n-ethylcarboxamide)
| Article | Year |
|---|---|
Fluorescent ligands for adenosine receptors.
Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 2013 |
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
6 other study(ies) available for sch 58261 and adenosine-5'-(n-ethylcarboxamide)
| Article | Year |
|---|---|
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Humans; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Radioligand Assay; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Theophylline; Threonine; Tritium | 1994 |
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles | 1997 |
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium | 1999 |
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2000 |
2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.
Topics: Adenosine A2 Receptor Antagonists; Amines; Animals; Cell Line; Cricetinae; Cyclic AMP; Furans; Humans; Models, Molecular; Molecular Structure; Nicotinic Acids; Nitriles; Receptor, Adenosine A2A; Structure-Activity Relationship | 2008 |
Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Catalepsy; Cell Line; Cell Membrane; Chromatography, Thin Layer; Computer Simulation; Crystallography, X-Ray; Cyclic AMP; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Haloperidol; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Motor Activity; Protein Binding; Pyrimidines; Radioligand Assay; Structure-Activity Relationship; Thiones | 2010 |