Page last updated: 2024-09-05

sch 58261 and 2-chloroadenosine

sch 58261 has been researched along with 2-chloroadenosine in 3 studies

Compound Research Comparison

Studies (sch 58261)	Trials (sch 58261)	Recent Studies (post-2010) (sch 58261)	Studies (2-chloroadenosine)	Trials (2-chloroadenosine)	Recent Studies (post-2010) (2-chloroadenosine)
46	0	14	889	13	47

Protein Interaction Comparison

Protein	Taxonomy	2-chloroadenosine (IC50)
high affinity choline transporter 1 isoform a	Homo sapiens (human)	0.5377
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.037
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	0.16
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	0.16

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U	1
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW	1
de Lera Ruiz, M; Lim, YH; Zheng, J	1

Reviews

1 review(s) available for sch 58261 and 2-chloroadenosine

Article	Year
Adenosine A2A receptor as a drug discovery target. Journal of medicinal chemistry, 2014, May-08, Volume: 57, Issue:9 Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction	2014

Other Studies

2 other study(ies) available for sch 58261 and 2-chloroadenosine

Article	Year
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium	1999
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine. Molecular pharmacology, 2000, Volume: 58, Issue:6 Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine	2000

Article

Year

Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.

Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium

1999

Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.

Molecular pharmacology, 2000, Volume: 58, Issue:6

Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine

2000