sch 58261 has been researched along with 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine in 6 studies
| Studies (sch 58261) | Trials (sch 58261) | Recent Studies (post-2010) (sch 58261) | Studies (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine) | Trials (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine) | Recent Studies (post-2010) (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine) |
|---|---|---|---|---|---|
| 46 | 0 | 14 | 952 | 2 | 169 |
| Protein | Taxonomy | sch 58261 (IC50) | 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine (IC50) |
|---|---|---|---|
| Adenosine receptor A2a | Homo sapiens (human) | 0.019 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C | 1 |
| Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U | 1 |
| Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW | 1 |
| Gao, ZG; Jacobson, KA | 1 |
| de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
| Gaba, S; Gupta, GD; Monga, V; Patel, R; Saini, A; Singh, G | 1 |
3 review(s) available for sch 58261 and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
| Article | Year |
|---|---|
Adenosine receptors as therapeutic targets.
Topics: Animals; Disease; Drug Therapy; Humans; Ligands; Molecular Structure; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Structure-Activity Relationship | 2006 |
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
Adenosine receptor antagonists: Recent advances and therapeutic perspective.
Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Structure-Activity Relationship | 2022 |
3 other study(ies) available for sch 58261 and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
| Article | Year |
|---|---|
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles | 1997 |
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium | 1999 |
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2000 |