Page last updated: 2024-09-05

sch 51048 and triazoles

sch 51048 has been researched along with triazoles in 7 studies

Compound Research Comparison

Studies
(sch 51048)
Trials
(sch 51048)
Recent Studies (post-2010)
(sch 51048)
Studies
(triazoles)
Trials
(triazoles)
Recent Studies (post-2010) (triazoles)
70025,8082,25213,501

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allendoerfer, R; Graybill, JR; Loebenberg, D; Rinaldi, MG1
Clemons, KV; Homola, ME; Stevens, DA1
Picard, M; Sugar, AM1
Anaissie, EJ; Dignani, MC; Karyotakis, NC1
Blundell, P; Cacciapuoti, A; Girijavallabhan, VM; Guzik, H; Loebenberg, D; Lovey, RG; Parmegiani, RM; Saksena, AK1
Bennett, F; Cacciapuoti, A; Ganguly, AK; Girijavallabhan, VM; Hare, RS; Jao, E; Liu, YT; Loebenberg, D; Lovey, RG; Menzel, F; Moss, E; Nomeir, A; Patel, NM; Pike, R; Pinto, P; Saksena, AK; Wang, H1
Bartner, P; Bennett, F; Cacciapuoti, A; Ganguly, AK; Girijavallabhan, V; Hare, R; Heimark, L; Hilbert, M; Korfmacher, W; Kumari, P; Lin, CC; Liu, YT; Loebenberg, D; Lovey, R; McNamara, P; Miller, G; Nomeir, AA; Pickett, C; Pike, R; Pramanik, BN; Saksena, A; Veals, J; Wang, H1

Other Studies

7 other study(ies) available for sch 51048 and triazoles

ArticleYear
Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Evaluation; Female; Itraconazole; Lung Diseases, Fungal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Survival Rate; Triazoles

1995
Activities of the triazole SCH 51048 against Coccidioides immitis in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:5

    Topics: Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Female; Fluconazole; Half-Life; Itraconazole; Mice; Microbial Sensitivity Tests; Triazoles

1995
Treatment of murine pulmonary blastomycosis with SCH 51048, a broad-spectrum triazole antifungal agent.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:4

    Topics: Animals; Antifungal Agents; Blastomycosis; Lung Diseases, Fungal; Male; Mice; Mice, Inbred ICR; Triazoles

1995
SCH 51048, a new antifungal triazole active against hematogenous Candida krusei infections in neutropenic mice.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:3

    Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Fluconazole; Immunosuppression Therapy; Kidney; Male; Mice; Mice, Inbred Strains; Neutropenia; Triazoles

1995
Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.
    Bioorganic & medicinal chemistry letters, 2002, Jul-08, Volume: 12, Issue:13

    Topics: Antifungal Agents; Benzene; Binding Sites; Furans; In Vitro Techniques; Microbial Sensitivity Tests; Oxygen; Stereoisomerism; Structure-Activity Relationship; Triazoles

2002
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5].
    Bioorganic & medicinal chemistry letters, 2006, Jan-01, Volume: 16, Issue:1

    Topics: Alcohols; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Haplorhini; Humans; Immunosuppressive Agents; Mice; Models, Chemical; Time Factors; Triazoles

2006
Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).
    Journal of mass spectrometry : JMS, 2008, Volume: 43, Issue:4

    Topics: Animals; Antifungal Agents; Chromatography, High Pressure Liquid; Dogs; Drug Design; Macaca fascicularis; Male; Mass Spectrometry; Mice; Mice, Inbred Strains; Rabbits; Triazoles

2008