sch 51048 has been researched along with itraconazole in 3 studies
| Studies (sch 51048) | Trials (sch 51048) | Recent Studies (post-2010) (sch 51048) | Studies (itraconazole) | Trials (itraconazole) | Recent Studies (post-2010) (itraconazole) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 249 | 4 | 108 |
| 7 | 0 | 0 | 6,440 | 653 | 2,357 |
| Protein | Taxonomy | sch 51048 (IC50) | itraconazole (IC50) |
|---|---|---|---|
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 3.89 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 0.7 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.666 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.4256 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 0.2 | |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | 2.5676 | |
| Cruzipain | Trypanosoma cruzi | 3 | |
| Vasopressin V2 receptor | Homo sapiens (human) | 3.476 | |
| C-C chemokine receptor type 4 | Homo sapiens (human) | 3.2689 | |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | 3.6 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blundell, P; Cacciapuoti, A; Girijavallabhan, VM; Guzik, H; Loebenberg, D; Lovey, RG; Parmegiani, RM; Saksena, AK | 1 |
| Allendoerfer, R; Graybill, JR; Loebenberg, D; Rinaldi, MG | 1 |
| Clemons, KV; Homola, ME; Stevens, DA | 1 |
3 other study(ies) available for sch 51048 and itraconazole
| Article | Year |
|---|---|
Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.
Topics: Antifungal Agents; Benzene; Binding Sites; Furans; In Vitro Techniques; Microbial Sensitivity Tests; Oxygen; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2002 |
Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Evaluation; Female; Itraconazole; Lung Diseases, Fungal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Survival Rate; Triazoles | 1995 |
Activities of the triazole SCH 51048 against Coccidioides immitis in vitro and in vivo.
Topics: Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Female; Fluconazole; Half-Life; Itraconazole; Mice; Microbial Sensitivity Tests; Triazoles | 1995 |