Page last updated: 2024-09-05

sch 51048 and itraconazole

sch 51048 has been researched along with itraconazole in 3 studies

Compound Research Comparison

Studies
(sch 51048)
Trials
(sch 51048)
Recent Studies (post-2010)
(sch 51048)
Studies
(itraconazole)
Trials
(itraconazole)
Recent Studies (post-2010) (itraconazole)
7002494108
7006,4406532,357

Protein Interaction Comparison

ProteinTaxonomysch 51048 (IC50)itraconazole (IC50)
Tyrosine-protein kinase FynHomo sapiens (human)3.89
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.7
ATP-dependent translocase ABCB1Homo sapiens (human)1.666
Cytochrome P450 3A4Homo sapiens (human)0.4256
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.2
C-X-C chemokine receptor type 1Homo sapiens (human)2.5676
CruzipainTrypanosoma cruzi3
Vasopressin V2 receptorHomo sapiens (human)3.476
C-C chemokine receptor type 4Homo sapiens (human)3.2689
Lanosterol 14-alpha demethylaseHomo sapiens (human)3.6
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blundell, P; Cacciapuoti, A; Girijavallabhan, VM; Guzik, H; Loebenberg, D; Lovey, RG; Parmegiani, RM; Saksena, AK1
Allendoerfer, R; Graybill, JR; Loebenberg, D; Rinaldi, MG1
Clemons, KV; Homola, ME; Stevens, DA1

Other Studies

3 other study(ies) available for sch 51048 and itraconazole

ArticleYear
Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.
    Bioorganic & medicinal chemistry letters, 2002, Jul-08, Volume: 12, Issue:13

    Topics: Antifungal Agents; Benzene; Binding Sites; Furans; In Vitro Techniques; Microbial Sensitivity Tests; Oxygen; Stereoisomerism; Structure-Activity Relationship; Triazoles

2002
Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Evaluation; Female; Itraconazole; Lung Diseases, Fungal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Survival Rate; Triazoles

1995
Activities of the triazole SCH 51048 against Coccidioides immitis in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:5

    Topics: Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Female; Fluconazole; Half-Life; Itraconazole; Mice; Microbial Sensitivity Tests; Triazoles

1995