Page last updated: 2024-09-03

sch 42495 and cyclic gmp

sch 42495 has been researched along with cyclic gmp in 3 studies

Compound Research Comparison

Studies (sch 42495)	Trials (sch 42495)	Recent Studies (post-2010) (sch 42495)	Studies (cyclic gmp)	Trials (cyclic gmp)	Recent Studies (post-2010) (cyclic gmp)
18	5	0	22,346	333	4,062

Protein Interaction Comparison

Protein	Taxonomy	cyclic gmp (IC50)
Phosphodiesterase	Bos taurus (cattle)	0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	2.4

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ardeleani, G; Casati, C; Monopoli, A; Morganti, A; Ongini, E; Sala, C; Zanchetti, A	1
Masuo, K; Mikami, H; Nagano, M; Ogihara, T; Rakugi, H; Yu, H	1
Espiner, EA; Lainchbury, JG; Nicholls, MG; Richards, AM; Yandle, TG	1

Trials

2 trial(s) available for sch 42495 and cyclic gmp

Article	Year
Antihypertensive effects of the neutral endopeptidase inhibitor SCH 42495 in essential hypertension. American journal of hypertension, 1994, Volume: 7, Issue:11 Topics: Aged; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Female; Heart Rate; Humans; Hypertension; Male; Methionine; Middle Aged; Neprilysin	1994
Brain natriuretic peptide and neutral endopeptidase inhibition in left ventricular impairment. The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:2 Topics: Adult; Aged; Aldosterone; Blood Pressure; Cyclic GMP; Drug Synergism; Humans; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Natriuresis; Natriuretic Peptide, Brain; Neprilysin; Protease Inhibitors; Renin; Ventricular Dysfunction, Left	1999

Article

Year

Antihypertensive effects of the neutral endopeptidase inhibitor SCH 42495 in essential hypertension.

American journal of hypertension, 1994, Volume: 7, Issue:11

Topics: Aged; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Female; Heart Rate; Humans; Hypertension; Male; Methionine; Middle Aged; Neprilysin

1994

Brain natriuretic peptide and neutral endopeptidase inhibition in left ventricular impairment.

The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:2

Topics: Adult; Aged; Aldosterone; Blood Pressure; Cyclic GMP; Drug Synergism; Humans; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Natriuresis; Natriuretic Peptide, Brain; Neprilysin; Protease Inhibitors; Renin; Ventricular Dysfunction, Left

1999

Other Studies

1 other study(ies) available for sch 42495 and cyclic gmp

Article	Year
Hemodynamic and humoral effects of chronic treatment with the neutral endopeptidase inhibitor SCH 42495 in spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5 Topics: Administration, Oral; Analysis of Variance; Animals; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; Enalapril; Hemodynamics; Hypertension; Male; Methionine; Natriuresis; Neprilysin; Rats; Rats, Inbred SHR; Renin-Angiotensin System	1994

Article

Year

Hemodynamic and humoral effects of chronic treatment with the neutral endopeptidase inhibitor SCH 42495 in spontaneously hypertensive rats.

Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5

Topics: Administration, Oral; Analysis of Variance; Animals; Atrial Natriuretic Factor; Cyclic GMP; Diuresis; Enalapril; Hemodynamics; Hypertension; Male; Methionine; Natriuresis; Neprilysin; Rats; Rats, Inbred SHR; Renin-Angiotensin System

1994