sch 42495 has been researched along with aldosterone in 2 studies
| Studies (sch 42495) | Trials (sch 42495) | Recent Studies (post-2010) (sch 42495) | Studies (aldosterone) | Trials (aldosterone) | Recent Studies (post-2010) (aldosterone) |
|---|---|---|---|---|---|
| 18 | 5 | 0 | 25,333 | 1,517 | 4,169 |
| Protein | Taxonomy | sch 42495 (IC50) | aldosterone (IC50) |
|---|---|---|---|
| Mineralocorticoid receptor | Homo sapiens (human) | 0.0048 | |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | 0.043 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Espiner, EA; Lainchbury, JG; Nicholls, MG; Richards, AM; Yandle, TG | 1 |
| Burrell, LM; Farina, NK; Johnston, CI | 1 |
1 trial(s) available for sch 42495 and aldosterone
| Article | Year |
|---|---|
Brain natriuretic peptide and neutral endopeptidase inhibition in left ventricular impairment.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Cyclic GMP; Drug Synergism; Humans; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Natriuresis; Natriuretic Peptide, Brain; Neprilysin; Protease Inhibitors; Renin; Ventricular Dysfunction, Left | 1999 |
1 other study(ies) available for sch 42495 and aldosterone
| Article | Year |
|---|---|
Reversal of cardiac hypertrophy and fibrosis by S21402, a dual inhibitor of neutral endopeptidase and angiotensin converting enzyme in SHRs.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiomegaly; Enzyme Inhibitors; Fibrosis; Hypertension; Kidney; Male; Methionine; Myocardium; Neprilysin; Organ Size; Propionates; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin; Sulfhydryl Compounds | 2000 |