Compounds > sch 39370
Page last updated: 2024-09-03

sch 39370 and cyclic gmp

sch 39370 has been researched along with cyclic gmp in 6 studies

Compound Research Comparison

Studies
(sch 39370)		Trials
(sch 39370)		Recent Studies (post-2010)
(sch 39370)		Studies
(cyclic gmp)		Trials
(cyclic gmp)		Recent Studies (post-2010) (cyclic gmp)
251022,3463334,062

Protein Interaction Comparison

ProteinTaxonomysch 39370 (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's5 (83.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnston, CI; Murohara, Y1
Charles, CJ; Espiner, EA; Fitzpatrick, MA; Ikram, H; Rademaker, MT; Sybertz, E; Yandle, TG1
Fyhrquist, F; Helin, K; Saijonmaa, O; Sariola, H; Sybertz, EJ; Tikkanen, I; Tikkanen, T; Vemulapalli, S1
Cameron, VA; Charles, CJ; Espiner, EA; Richards, AM; Sybertz, EJ; Yandle, TG1
Barnett, A; Chiu, PJ; Foster, CJ; Haslanger, MF; Pitts, B; Sybertz, EJ; Vemulapalli, S; Watkins, RW1
Charles, CJ; Espiner, EA; Fitzpatrick, MA; Nicholls, MG; Rademaker, MT; Richards, AM; Sybertz, E1

Other Studies

6 other study(ies) available for sch 39370 and cyclic gmp

ArticleYear
Effect of neutral endopeptidase inhibitor in rats with congestive heart failure.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:5

    Topics: Animals; Atrial Natriuretic Factor; Cardiac Output; Cyclic GMP; Dipeptides; Female; Heart Failure; Hemodynamics; Kidney; Pharmaceutical Vehicles; Protease Inhibitors; Rats; Rats, Inbred Strains; Vascular Resistance; Ventricular Function, Left

1992
Acute hemodynamic, hormonal, and renal effects of neutral endopeptidase inhibition in ovine heart failure.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:4

    Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Blood Pressure; Cattle; Cyclic GMP; Dipeptides; Diuresis; Female; Furosemide; Heart Failure; Hemodynamics; Injections, Intravenous; Natriuresis; Neprilysin

1992
Prolonged neutral endopeptidase inhibition in heart failure.
    European journal of pharmacology, 1991, May-30, Volume: 198, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Chromatography, High Pressure Liquid; Cyclic GMP; Dipeptides; Endopeptidases; Heart Failure; Hemodynamics; Kidney; Kidney Function Tests; Male; Metalloendopeptidases; Protease Inhibitors; Pulse; Rats; Rats, Inbred Strains; Renin; Water-Electrolyte Balance

1991
Hemodynamic and hormonal effects of neutral endopeptidase inhibitor SCH 39370 in sheep.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:5

    Topics: Aldosterone; Analysis of Variance; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dipeptides; Female; Hemodynamics; Hormones; Hydrocortisone; Neprilysin; Polygeline; Sheep

1991
SCH 39370, a neutral metalloendopeptidase inhibitor, potentiates biological responses to atrial natriuretic factor and lowers blood pressure in desoxycorticosterone acetate-sodium hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Desoxycorticosterone; Dipeptides; Drug Synergism; Hypertension; Kidney; Male; Metalloendopeptidases; Rats; Rats, Inbred SHR; Sodium

1989
Comparison of chronic neutral endopeptidase inhibition and furosemide in an ovine model of heart failure.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Captopril; Cyclic GMP; Dipeptides; Diuretics; Dose-Response Relationship, Drug; Female; Furosemide; Heart Failure; Hemodynamics; Neprilysin; Sheep

1996