sch 34826 has been researched along with cyclic gmp in 6 studies
| Studies (sch 34826) | Trials (sch 34826) | Recent Studies (post-2010) (sch 34826) | Studies (cyclic gmp) | Trials (cyclic gmp) | Recent Studies (post-2010) (cyclic gmp) |
|---|---|---|---|---|---|
| 31 | 2 | 0 | 22,346 | 333 | 4,062 |
| Protein | Taxonomy | sch 34826 (IC50) | cyclic gmp (IC50) |
|---|---|---|---|
| Phosphodiesterase | Bos taurus (cattle) | 0.1 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | 2.4 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | 2.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crozier, IG; Espiner, EA; Frampton, C; Ikram, H; Kosoglou, T; Rallings, M; Richards, AM; Yandle, TG | 1 |
| Chen, YF; Esunge, P; Jin, H; Mathews, C; Oparil, S; Wyss, JM; Yang, R | 1 |
| Brown, A; Chiu, PJ; Griscti, K; Sybertz, EJ; Vemulapalli, S | 1 |
| Chiu, PJ; Haslanger, MF; Sybertz, EJ; Vemulapalli, S; Watkins, R | 1 |
| Helin, K | 1 |
| Arnal, F; Hill, NS; Klinger, JR; Petit, RD; Warburton, RR; Wrenn, DS | 1 |
1 trial(s) available for sch 34826 and cyclic gmp
| Article | Year |
|---|---|
Acute inhibition of endopeptidase 24.11 in essential hypertension: SCH 34826 enhances atrial natriuretic peptide and natriuresis without lowering blood pressure.
Topics: Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dipeptides; Double-Blind Method; Epinephrine; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuresis; Neprilysin; Norepinephrine; Renin-Angiotensin System | 1992 |
5 other study(ies) available for sch 34826 and cyclic gmp
| Article | Year |
|---|---|
Effects of acute and chronic blockade of neutral endopeptidase with Sch 34826 on NaCl-sensitive hypertension in spontaneously hypertensive rats.
Topics: Administration, Oral; Analgesics; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dipeptides; Hypertension; Male; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium Chloride | 1992 |
The blood pressure and renal responses to SCH 34826, a neutral metalloendopeptidase inhibitor, and C-ANF (4-23) in Doca-salt hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Desoxycorticosterone; Dioxolanes; Dipeptides; Hypertension; Kidney; Male; Neprilysin; Peptide Fragments; Rats | 1991 |
Atrial natriuretic factor-potentiating and antihypertensive activity of SCH 34826. An orally active neutral metalloendopeptidase inhibitor.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dioxoles; Dipeptides; Drug Synergism; Hemodynamics; Hypertension; Kidney; Male; Neprilysin; Rats; Rats, Inbred SHR | 1990 |
Concurrent neutral endopeptidase and ACE inhibition in experimental heart failure: renal and hormonal effects.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Chronic Disease; Cyclic GMP; Dioxolanes; Dipeptides; Drug Therapy, Combination; Heart Failure; Kidney; Male; Neprilysin; Rats; Rats, Wistar | 1993 |
Neutral endopeptidase inhibition attenuates development of hypoxic pulmonary hypertension in rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Cyclic GMP; Dioxolanes; Dipeptides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Male; Muscle, Smooth, Vascular; Myocardium; Neprilysin; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1993 |