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sch 34826 and atrial natriuretic factor

sch 34826 has been researched along with atrial natriuretic factor in 14 studies

Compound Research Comparison

Studies (sch 34826)	Trials (sch 34826)	Recent Studies (post-2010) (sch 34826)	Studies (atrial natriuretic factor)	Trials (atrial natriuretic factor)	Recent Studies (post-2010) (atrial natriuretic factor)
31	2	0	15,455	1,105	1,760

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	14 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cigola, E; Monopoli, A; Olivetti, G; Ongini, E	1
Crozier, IG; Espiner, EA; Frampton, C; Ikram, H; Kosoglou, T; Rallings, M; Richards, AM; Yandle, TG	1
Chen, YF; Esunge, P; Jin, H; Mathews, C; Oparil, S; Wyss, JM; Yang, R	1
Morice, AH; Sheedy, W; Stewart, AG; Thompson, JS	1
Brown, A; Chiu, PJ; Griscti, K; Sybertz, EJ; Vemulapalli, S	1
Brunner, HR; Burnier, M; Ganslmayer, M; Gould, A; Kosoglou, T; Nussberger, J; Perret, F; Porchet, M; Waeber, B	1
Sybertz, EJ	1
Furuhashi, N; Yajima, A	1
Chiu, PJ; Sybertz, EJ; Vemulapalli, S; Watkins, RW	2
Chiu, PJ; Haslanger, MF; Sybertz, EJ; Vemulapalli, S; Watkins, R	1
Fyhrquist, F; Helin, K; Hohenthal, U; Tikkanen, I	1
Helin, K	1
Arnal, F; Hill, NS; Klinger, JR; Petit, RD; Warburton, RR; Wrenn, DS	1

Reviews

1 review(s) available for sch 34826 and atrial natriuretic factor

Article	Year
SCH 34826: an overview of its profile as a neutral endopeptidase inhibitor and ANF potentiator. Clinical nephrology, 1991, Volume: 36, Issue:4 Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Dioxolanes; Dipeptides; Drug Synergism; Heart Failure; Humans; Hypertension; Neprilysin; Prodrugs; Rats	1991

Trials

2 trial(s) available for sch 34826 and atrial natriuretic factor

Article	Year
Acute inhibition of endopeptidase 24.11 in essential hypertension: SCH 34826 enhances atrial natriuretic peptide and natriuresis without lowering blood pressure. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5 Topics: Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dipeptides; Double-Blind Method; Epinephrine; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuresis; Neprilysin; Norepinephrine; Renin-Angiotensin System	1992
Effects of SCH 34826, an orally active inhibitor of atrial natriuretic peptide degradation, in healthy volunteers. Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:2 Topics: Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Dioxolanes; Dipeptides; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Male; Natriuresis; Reference Values; Renal Circulation; Sodium, Dietary	1991

Article

Year

Acute inhibition of endopeptidase 24.11 in essential hypertension: SCH 34826 enhances atrial natriuretic peptide and natriuresis without lowering blood pressure.

Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5

Topics: Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dipeptides; Double-Blind Method; Epinephrine; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuresis; Neprilysin; Norepinephrine; Renin-Angiotensin System

1992

Effects of SCH 34826, an orally active inhibitor of atrial natriuretic peptide degradation, in healthy volunteers.

Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:2

Topics: Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Dioxolanes; Dipeptides; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Male; Natriuresis; Reference Values; Renal Circulation; Sodium, Dietary

1991

Other Studies

11 other study(ies) available for sch 34826 and atrial natriuretic factor

Article	Year
The neutral endopeptidase inhibitor, SCH 34826, reduces left ventricular hypertrophy in spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:3 Topics: Animals; Atrial Natriuretic Factor; Cardiomegaly; Dioxolanes; Dipeptides; Hemodynamics; Hypertension; Male; Microscopy, Electron; Myocardium; Neprilysin; Rats; Rats, Inbred SHR; Ventricular Function, Left	1992
Effects of acute and chronic blockade of neutral endopeptidase with Sch 34826 on NaCl-sensitive hypertension in spontaneously hypertensive rats. American journal of hypertension, 1992, Volume: 5, Issue:4 Pt 1 Topics: Administration, Oral; Analgesics; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dipeptides; Hypertension; Male; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium Chloride	1992
Effects of SCH 34826, a neutral endopeptidase inhibitor, on hypoxic pulmonary vascular remodelling. Pulmonary pharmacology, 1992, Volume: 5, Issue:2 Topics: Analgesics; Animals; Atrial Natriuretic Factor; Dioxolanes; Dipeptides; Hypoxia; Injections, Subcutaneous; Male; Neprilysin; Pulmonary Artery; Rats; Rats, Inbred Strains	1992
The blood pressure and renal responses to SCH 34826, a neutral metalloendopeptidase inhibitor, and C-ANF (4-23) in Doca-salt hypertensive rats. Life sciences, 1991, Volume: 49, Issue:5 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Desoxycorticosterone; Dioxolanes; Dipeptides; Hypertension; Kidney; Male; Neprilysin; Peptide Fragments; Rats	1991
[Enzyme inhibitor in the treatment of preeclampsia]. Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9 Topics: Atrial Natriuretic Factor; Dioxolanes; Dipeptides; Female; Humans; Methacrylates; Pre-Eclampsia; Pregnancy; Thromboxane-A Synthase	1991
Neutral metalloendopeptidase inhibitors as ANF potentiators: sites and mechanisms of action. Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:10 Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Desoxycorticosterone; Dioxolanes; Dipeptides; Drug Synergism; Hypertension; Iodine Radioisotopes; Kinins; Male; Metalloendopeptidases; Rats; Rats, Inbred Strains; Thiorphan	1991
Neutral metalloendopeptidase inhibition: a novel means of circulatory modulation. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1990, Volume: 8, Issue:7 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Desoxycorticosterone; Dioxolanes; Dipeptides; Hypertension; Male; Methionine; Neprilysin; Rats; Rats, Inbred Strains; Sodium, Dietary	1990
Atrial natriuretic factor-potentiating and antihypertensive activity of SCH 34826. An orally active neutral metalloendopeptidase inhibitor. Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:2 Topics: Administration, Oral; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dioxolanes; Dioxoles; Dipeptides; Drug Synergism; Hemodynamics; Hypertension; Kidney; Male; Neprilysin; Rats; Rats, Inbred SHR	1990
Inhibition of either angiotensin-converting enzyme or neutral endopeptidase induces both enzymes. European journal of pharmacology, 1994, Oct-24, Volume: 264, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Captopril; Dioxolanes; Dipeptides; Disease Models, Animal; Enzyme Induction; Heart Failure; Kidney; Ligation; Lung; Male; Neprilysin; Organ Size; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Wistar; Regression Analysis; Renin	1994
Concurrent neutral endopeptidase and ACE inhibition in experimental heart failure: renal and hormonal effects. Scandinavian journal of clinical and laboratory investigation, 1993, Volume: 53, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Chronic Disease; Cyclic GMP; Dioxolanes; Dipeptides; Drug Therapy, Combination; Heart Failure; Kidney; Male; Neprilysin; Rats; Rats, Wistar	1993
Neutral endopeptidase inhibition attenuates development of hypoxic pulmonary hypertension in rats. Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:4 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Cyclic GMP; Dioxolanes; Dipeptides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Male; Muscle, Smooth, Vascular; Myocardium; Neprilysin; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger	1993