Page last updated: 2024-09-02

sch 28080 and histamine

sch 28080 has been researched along with histamine in 13 studies

Compound Research Comparison

Studies
(sch 28080)
Trials
(sch 28080)
Recent Studies (post-2010)
(sch 28080)
Studies
(histamine)
Trials
(histamine)
Recent Studies (post-2010) (histamine)
21702037,7181,3723,457

Protein Interaction Comparison

ProteinTaxonomysch 28080 (IC50)histamine (IC50)
Histamine H1 receptorRattus norvegicus (Norway rat)0.1585
Histamine H1 receptorHomo sapiens (human)0.1585

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fryklund, J; Gedda, K; Sachs, G; Scott, D; Wallmark, B1
ChacĂ­n, J; Lobo, P; Subero, O1
Castrovilly, L; Scott, CK; Sundell, E1
Blissard, D; Cragoe, EJ; Muallem, S; Sachs, G1
Bristol, JA; Conn, DJ; Domalski, MS; Elliott, AJ; Guzik, H; Kaminski, JJ; Lovey, RG; Puchalski, C; Solomon, DM; Wong, SC1
Barnett, A; Casciano, C; Chiu, PJ; Long, JF; Tetzloff, G1
Chiu, PJ; Derelanko, MJ; Long, JF; Steinberg, M1
Asano, S; Morii, M; Ohshika, M; Takeguchi, N; Tomiyama, Y1
Bachmann, O; Gregor, M; Lamprecht, G; Seidler, U; Siegel, WK; Sonnentag, T; Weichert, A1
Fischer, H; Illek, B; Widdicombe, JH1
Andersson, K; Geibel, JP; Kirchhoff, P; Kosiek, O; Sidani, S; Socrates, T1
Caroppo, R; Colella, M; Curci, S; Debellis, L; Fistetto, G; Gerbino, A; Hofer, AM1
Arikawa, Y; Hirase, K; Hori, Y; Imanishi, A; Inatomi, N; Kajino, M; Matsukawa, J; Nishida, H; Tsukimi, Y1

Other Studies

13 other study(ies) available for sch 28080 and histamine

ArticleYear
Coupling of H(+)-K(+)-ATPase activity and glucose oxidation in gastric glands.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: Adenosine Triphosphatases; Aminopyrine; Ammonia; Animals; Anti-Ulcer Agents; Atropine; Bucladesine; Carbachol; Carbon Dioxide; Cimetidine; Gastric Mucosa; Glucose; Glycolysis; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; In Vitro Techniques; Kinetics; Models, Biological; Omeprazole; Oxygen Consumption; Rats

1990
Ca2+ requirement for metabolic effects of secretagogues in the amphibian gastric mucosa.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 1

    Topics: Acetates; Animals; Anti-Ulcer Agents; Bufo marinus; Butyrates; Butyric Acid; Calcimycin; Calcium; Gastric Juice; Gastric Mucosa; Glycogen; Histamine; Imidazoles; In Vitro Techniques; Kinetics; Omeprazole; Oxygen Consumption; Potassium; Theophylline

1989
Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080.
    Biochemical pharmacology, 1987, Jan-01, Volume: 36, Issue:1

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Bucladesine; Dithiothreitol; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; Mercaptoethanol; Microsomes; Omeprazole; Pyrazines; Rabbits

1987
Activation of the Na+/H+ and Cl-/HCO3- exchange by stimulation of acid secretion in the parietal cell.
    The Journal of biological chemistry, 1988, Oct-15, Volume: 263, Issue:29

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Aminacrine; Animals; Anti-Ulcer Agents; Bicarbonates; Cell Membrane; Chlorides; Cimetidine; Cytosol; Gastric Acid; Histamine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Kinetics; Parietal Cells, Gastric; Rabbits; Sodium

1988
Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Biological Assay; Chemical Phenomena; Chemistry; Dogs; Gastric Mucosa; Histamine; Imidazoles; Ligation; Male; Pyloric Antrum; Pyridines; Rats; Structure-Activity Relationship

1985
Studies on the mechanisms of the antisecretory and cytoprotective actions of SCH 28080.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Bicarbonates; Bucladesine; Dogs; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; Imidazoles; Male; Methacholine Chloride; Methacholine Compounds; Mucus; Rats; Theophylline

1983
Gastric antisecretory and cytoprotective activities of SCH 28080.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine; Imidazoles; Indomethacin; Male; Membrane Potentials; Rats; Stomach Ulcer; Stress, Physiological

1983
The apical chloride channel as part of the function of gastric H+,K(+)-ATPase.
    The Japanese journal of physiology, 1994, Volume: 44 Suppl 2

    Topics: Animals; Anti-Ulcer Agents; Chloride Channels; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; Membranes; Potassium; Proton Pumps; Stomach

1994
Different acid secretagogues activate different Na+/H+ exchanger isoforms in rabbit parietal cells.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Aminopyrine; Animals; Biological Transport; Carbachol; Cells, Cultured; Colforsin; Cytochalasin D; Gastric Acid; Guanidines; Histamine; Imidazoles; Kinetics; Omeprazole; Parietal Cells, Gastric; Rabbits; Sodium-Hydrogen Exchangers; Sulfones; Time Factors

1998
Acid secretion and proton conductance in human airway epithelium.
    American journal of physiology. Cell physiology, 2002, Volume: 282, Issue:4

    Topics: Acids; Adenosine Triphosphate; Amiloride; Biological Transport; Cells, Cultured; Chlorides; Diffusion Chambers, Culture; Diuretics; Enzyme Inhibitors; Histamine; Humans; Hydrogen-Ion Concentration; Imidazoles; Mast Cells; Membrane Potentials; Patch-Clamp Techniques; Protons; Respiratory Mucosa; Trachea; Zinc Compounds

2002
Characteristics of the K+-competitive H+,K+-ATPase inhibitor AZD0865 in isolated rat gastric glands.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 291, Issue:5

    Topics: Animals; Binding, Competitive; Diagnostic Imaging; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Omeprazole; Potassium; Proton Pump Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley

2006
Real time measurements of water flow in amphibian gastric glands: modulation via the extracellular Ca2+-sensing receptor.
    The Journal of biological chemistry, 2007, May-04, Volume: 282, Issue:18

    Topics: Amphibian Proteins; Animals; Chromans; Cyclic AMP; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; Ion Transport; Microelectrodes; Osmosis; Potassium Channel Blockers; Proton Pump Inhibitors; Rana esculenta; Receptors, Calcium-Sensing; Sulfonamides; Water

2007
1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438), a novel and potent potassium-competitive acid blocker for the treatment of acid-related diseases.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Dithiothreitol; Gastric Acid; Gastric Mucosa; Histamine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Kinetics; Lansoprazole; Ligation; Male; Potassium; Proton Pump Inhibitors; Pylorus; Pyrroles; Rats; Rats, Sprague-Dawley; Stomach; Sulfonamides; Swine

2010