sch 28080 has been researched along with glutamic acid in 5 studies
| Studies (sch 28080) | Trials (sch 28080) | Recent Studies (post-2010) (sch 28080) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 217 | 0 | 20 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | sch 28080 (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Pont, JJ; Klaassen, CH; Swarts, HP | 1 |
| De Pont, JJ; Hermsen, HP; Koenderink, JB; Swarts, HG | 1 |
| de Pont, JJ; Hermsen, HP; Koenderink, JB; Swarts, HG; Willems, PH | 1 |
| De Pont, JJ; Hermsen, HP; Koenderink, JB; Swarts, HG; Wassink, L; Willems, PH | 1 |
| Dürr, KL; Friedrich, T; Seuffert, I | 1 |
5 other study(ies) available for sch 28080 and glutamic acid
| Article | Year |
|---|---|
Involvement of glutamic acid 820 in K+ and SCH 28080 binding to gastric H+,K(+)-ATPase.
Topics: Amino Acid Substitution; Animals; Cell Line; Cell Membrane; Enzyme Inhibitors; Gastric Mucosa; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Ouabain; Point Mutation; Potassium; Recombinant Proteins; Spodoptera; Swine; Transfection | 1997 |
The negative charge of glutamic acid-820 in the gastric H+,K+-ATPase alpha-subunit is essential for K+ activation of the enzyme activity.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Baculoviridae; Electrochemistry; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Potassium; Proton Pump Inhibitors; Recombinant Proteins; Spodoptera; Stomach; Structure-Activity Relationship | 1998 |
Conformation-dependent inhibition of gastric H+,K+-ATPase by SCH 28080 demonstrated by mutagenesis of glutamic acid 820.
Topics: Adenosine Triphosphate; Animals; Catalysis; Cells, Cultured; Enzyme Inhibitors; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Imidazoles; Mutagenesis; Phosphates; Phosphorylation; Potassium; Protein Conformation; Proton Pump Inhibitors; Rats; Recombinant Proteins; Stomach; Time Factors; Vanadates | 1999 |
Mimicking of K+ activation by double mutation of glutamate 795 and glutamate 820 of gastric H+,K+-ATPase.
Topics: Adenosine Triphosphatases; Amino Acid Substitution; Animals; Baculoviridae; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Hydroxylamine; Imidazoles; Mutagenesis, Site-Directed; Phosphorylation; Potassium; Proton Pump Inhibitors; Rats; Spodoptera; Stomach | 2001 |
Deceleration of the E1P-E2P transition and ion transport by mutation of potentially salt bridge-forming residues Lys-791 and Glu-820 in gastric H+/K+-ATPase.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Electrophysiology; Gastric Mucosa; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Imidazoles; Lysine; Molecular Sequence Data; Mutation; Oocytes; Protein Conformation; Rats; Rhodamines; Salts; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Xenopus | 2010 |