Page last updated: 2024-08-16

sch 16134 and flurazepam

sch 16134 has been researched along with flurazepam in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199019 (73.08)18.7374
1990's4 (15.38)18.2507
2000's1 (3.85)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mahowald, MW; Walsh, JK1
Battista, D; Hilbert, JM1
Dement, WC1
Roehrs, TA; Roth, T1
Kauert, G; Klausnitzer, W; Schaffler, K; Wauschkuhn, CH1
Bixler, EO; Jacoby, JA; Kales, A; Kales, JD; Soldatos, CR1
Gevins, AS; Ragsdale, SD; Stone, RK1
Barnett, A; Ongini, E1
Ellinwood, EH; Gupta, SK1
Kawasaki, H; Nuki, C; Ohno, H; Takasaki, K; Urabe, M; Yamamoto, R1
Barnett, A; Hilbert, JM; Iorio, L; Moritzen, V; Symchowicz, S; Zampaglione, N1
Kales, A; Kales, JD; Soldatos, CR1
Bixler, EO; Kales, A; Soldatos, CR; Vela-Bueno, A1
Fumagalli, R; Iuliano, E; Ongini, E; Racagni, G1
Carskadon, M; Dement, W; Seidel, W1
Bixler, EO; Kales, A; Kales, JD; Soldatos, CR1
Sieghart, W1
Mariotti, M; Ongini, E1
Gural, RP; Hilbert, JM; Symchowicz, S; Zampaglione, N1
Chung, M; Gural, R; Hilbert, JM; Radwanski, E; Symchowicz, S; Zampaglione, N1
Chung, M; Gural, RP; Hilbert, JM; Radwanski, E; Symchowicz, S; Zampaglione, N1
Chung, M; Gural, R; Hilbert, JM; Maier, G; Symchowicz, S; Zampaglione, N1
Bixler, EO; Jacoby, J; Kales, A; Kales, JD; Soldatos, CR; Vela-Bueno, A1
Aoshima, T; Fukasawa, T; Kanno, M; Kato, K; Otani, K; Suzuki, A; Yasui-Furukori, N1
Ohno, Y; Yamaguchi, K; Zhou, J1

Reviews

5 review(s) available for sch 16134 and flurazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics.
    The Journal of clinical psychiatry, 1991, Volume: 52 Suppl

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cricetinae; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Mice; Molecular Structure; Rats; Saimiri; Sleep Initiation and Maintenance Disorders; Tissue Distribution

1991
A review of the safety profiles of benzodiazepine hypnotics.
    The Journal of clinical psychiatry, 1991, Volume: 52 Suppl

    Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Central Nervous System; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Middle Aged; Psychomotor Performance; Sleep; Sleep Initiation and Maintenance Disorders; Temazepam; Triazolam

1991
Rebound insomnia and elimination half-life: assessment of individual subject response.
    Journal of clinical pharmacology, 1985, Volume: 25, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Half-Life; Humans; Lorazepam; Midazolam; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors; Triazolam

1985
Behavioral side effects of benzodiazepine hypnotics.
    Clinical neuropharmacology, 1985, Volume: 8 Suppl 1

    Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; Psychomotor Disorders; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Substance-Related Disorders; Triazolam

1985

Trials

3 trial(s) available for sch 16134 and flurazepam

ArticleYear
Objective measurements of daytime sleepiness and performance comparing quazepam with flurazepam in two adult populations using the Multiple Sleep Latency Test.
    The Journal of clinical psychiatry, 1991, Volume: 52 Suppl

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Anxiety Agents; Benzodiazepines; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Male; Middle Aged; Placebos; Psychomotor Performance; Sleep; Sleep Initiation and Maintenance Disorders

1991
Rebound insomnia and elimination half-life: assessment of individual subject response.
    Journal of clinical pharmacology, 1985, Volume: 25, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Half-Life; Humans; Lorazepam; Midazolam; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors; Triazolam

1985
Effects of itraconazole on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Benzodiazepines; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Itraconazole; Male; Psychomotor Performance; Sleep

2003

Other Studies

19 other study(ies) available for sch 16134 and flurazepam

ArticleYear
Avoiding the blanket approach to insomnia. Targeted therapy for specific causes.
    Postgraduate medicine, 1991, Volume: 90, Issue:1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Diagnosis, Differential; Estazolam; Flurazepam; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Temazepam; Triazolam

1991
Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Electrooculography; Flurazepam; Hemodynamics; Humans; Male; Psychomotor Performance; Reaction Time; Respiration; Substance Withdrawal Syndrome

1989
Differentiating the effects of three benzodiazepines on non-REM sleep EEG spectra. A neural-network pattern classification analysis.
    Neuropsychobiology, 1988, Volume: 19, Issue:2

    Topics: Adult; Algorithms; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Electroencephalography; Evoked Potentials; Flurazepam; Humans; Male; Nerve Net; Nervous System; Signal Processing, Computer-Assisted; Sleep Stages; Triazolam

1988
Hypnotic specificity of benzodiazepines.
    Clinical neuropharmacology, 1985, Volume: 8 Suppl 1

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Cats; Diazepam; Electroencephalography; Flurazepam; Hypnotics and Sedatives; Receptors, GABA-A; Sleep

1985
Liquid chromatographic assay and pharmacokinetics of quazepam and its metabolites following sublingual administration of quazepam.
    Pharmaceutical research, 1988, Volume: 5, Issue:6

    Topics: Administration, Sublingual; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Flurazepam; Humans; Male

1988
[Electroencephalographic study of Sch 161 (quazepam), a new benzodiazepine hypnotic, in rats and rabbits].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1987, Volume: 90, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Flurazepam; Hypnotics and Sedatives; Photic Stimulation; Rabbits; Rats; Reticular Formation; Sound

1987
Relationships of brain and plasma levels of quazepam, flurazepam, and their metabolites with pharmacological activity in mice.
    Life sciences, 1986, Jul-14, Volume: 39, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Dose-Response Relationship, Drug; Electroshock; Flurazepam; Male; Metabolic Clearance Rate; Mice; Seizures

1986
Quazepam: sleep laboratory studies of effectiveness and withdrawal.
    Clinical neuropharmacology, 1985, Volume: 8 Suppl 1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome

1985
Effects of quazepam and flurazepam on GABA-ergic transmission in mouse cerebellum: relationship between biochemical and behavioral activity.
    Pharmacological research communications, 1981, Volume: 13, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Flurazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Cell Surface; Receptors, GABA-A

1981
Daytime alertness, insomnia, and benzodiazepines.
    Sleep, 1982, Volume: 5 Suppl 1

    Topics: Adult; Anti-Anxiety Agents; Arousal; Benzodiazepines; Double-Blind Method; Flurazepam; Humans; Lorazepam; Male; Oxazepam; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazolam; Wakefulness

1982
Early morning insomnia with rapidly eliminated benzodiazepines.
    Science (New York, N.Y.), 1983, Apr-01, Volume: 220, Issue:4592

    Topics: Anti-Anxiety Agents; Benzodiazepines; Flurazepam; Half-Life; Humans; Midazolam; Sleep; Sleep Initiation and Maintenance Disorders; Triazolam

1983
Several new benzodiazepines selectively interact with a benzodiazepine receptor subtype.
    Neuroscience letters, 1983, Jul-15, Volume: 38, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cerebellum; Flunitrazepam; Flurazepam; Hippocampus; Membranes; Rats; Receptors, Cell Surface; Receptors, GABA-A

1983
Differential effects of benzodiazepines on EEG activity and hypnogenic mechanisms of the brain stem in cats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 264, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Stem; Cats; Decerebrate State; Diazepam; Electroencephalography; Flurazepam; Pentobarbital; Sleep

1983
Excretion of quazepam into human breast milk.
    Journal of clinical pharmacology, 1984, Volume: 24, Issue:10

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Female; Flurazepam; Humans; Milk, Human

1984
Quazepam kinetics in the elderly.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:4

    Topics: Absorption; Administration, Oral; Aged; Aging; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chromatography, Gas; Female; Flurazepam; Half-Life; Humans; Kinetics; Male

1984
Multiple-dose quazepam kinetics.
    Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:4

    Topics: Absorption; Administration, Oral; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flurazepam; Humans; Kinetics; Male

1984
Effect of sleep on quazepam kinetics.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1

    Topics: Absorption; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flurazepam; Half-Life; Humans; Kinetics; Male; Random Allocation; Sleep; Time Factors

1984
Quazepam and flurazepam: long-term use and extended withdrawal.
    Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Drug Evaluation; Flurazepam; Half-Life; Humans; Middle Aged; Sleep; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors

1982
Quantitative analysis of quazepam and its metabolites in human blood, urine, and bile by liquid chromatography-tandem mass spectrometry.
    Forensic science international, 2014, Volume: 241

    Topics: Benzodiazepines; Benzodiazepinones; Bile; Chromatography, Liquid; Flurazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Male; Middle Aged; Molecular Structure; Tandem Mass Spectrometry

2014