sch 16134 has been researched along with 2-oxoquazepam in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (55.56) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arnold, J | 1 |
| Battista, D; Hilbert, JM | 1 |
| Kales, A | 1 |
| Kauert, G; Klausnitzer, W; Schaffler, K; Wauschkuhn, CH | 1 |
| Barnett, A; Billard, W; Chipkin, R; Crosby, G; Iorio, L | 1 |
| Biggio, G; Concas, A; Corda, MG; Crisponi, G; Giorgi, O; Nurchi, V; Ongini, E; Pintori, T; Sanna, E | 1 |
| Ellinwood, EH; Gupta, SK | 1 |
| Aubert, C; Ba, B; Bun, H; Cano, JP; Coassolo, P | 1 |
| Sieghart, W | 1 |
| Gural, RP; Hilbert, JM; Symchowicz, S; Zampaglione, N | 1 |
| Chung, M; Gural, R; Hilbert, JM; Radwanski, E; Symchowicz, S; Zampaglione, N | 1 |
| Chung, M; Gural, RP; Hilbert, JM; Radwanski, E; Symchowicz, S; Zampaglione, N | 1 |
| Chung, M; Gural, R; Hilbert, JM; Maier, G; Symchowicz, S; Zampaglione, N | 1 |
| Kaneko, S; Kondo, T; Mihara, K; Ono, S; Takahata, T; Tateishi, T; Yasui-Furukori, N | 1 |
| Aoshima, T; Fukasawa, T; Kanno, M; Kato, K; Otani, K; Suzuki, A; Yasui-Furukori, N | 1 |
| Araki, N; Cui, Y; Fujimura, A; Harada, K; Kawaguchi, A; Ohmori, M; Sugimoto, K; Tsuruoka, S | 1 |
| Hasegawa, C; Hayashida, M; Kurosaki, K; Ohno, Y; Shinozuka, T; Tanaka, E; Terada, M | 1 |
| Ohno, Y; Yamaguchi, K; Zhou, J | 1 |
3 review(s) available for sch 16134 and 2-oxoquazepam
| Article | Year |
|---|---|
Determinants of pharmacologic effects and toxicity of benzodiazepine hypnotics: role of lipophilicity and plasma elimination rates.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Blood-Brain Barrier; Half-Life; Humans; Hypnotics and Sedatives; Kinetics; Lipid Metabolism; Receptors, GABA-A; Solubility | 1991 |
Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cricetinae; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Mice; Molecular Structure; Rats; Saimiri; Sleep Initiation and Maintenance Disorders; Tissue Distribution | 1991 |
Quazepam: hypnotic efficacy and side effects.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chemical Phenomena; Chemistry; Half-Life; Humans; Hypnotics and Sedatives; Risk Factors; Sleep Initiation and Maintenance Disorders | 1990 |
3 trial(s) available for sch 16134 and 2-oxoquazepam
| Article | Year |
|---|---|
Effect of dietary fat content in meals on pharmacokinetics of quazepam.
Topics: Adult; Anti-Anxiety Agents; Area Under Curve; Benzodiazepines; Cross-Over Studies; Dietary Fats; Fasting; Food-Drug Interactions; Half-Life; Humans; Hypnotics and Sedatives; Male; Postprandial Period; Time Factors | 2002 |
Effects of itraconazole on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug.
Topics: Administration, Oral; Adult; Area Under Curve; Benzodiazepines; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Itraconazole; Male; Psychomotor Performance; Sleep | 2003 |
Interaction between grapefruit juice and hypnotic drugs: comparison of triazolam and quazepam.
Topics: Adult; Analysis of Variance; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Beverages; Chromatography, High Pressure Liquid; Citrus paradisi; Cross-Over Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Food-Drug Interactions; Half-Life; Humans; Hypnotics and Sedatives; Male; Metabolic Clearance Rate; Time Factors; Triazolam | 2006 |
12 other study(ies) available for sch 16134 and 2-oxoquazepam
| Article | Year |
|---|---|
Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Electrooculography; Flurazepam; Hemodynamics; Humans; Male; Psychomotor Performance; Reaction Time; Respiration; Substance Withdrawal Syndrome | 1989 |
Selective affinity of the benzodiazepines quazepam and 2-oxo-quazepam for BZ1 binding site and demonstration of 3H-2-oxo-quazepam as a BZ1 selective radioligand.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Flunitrazepam; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1988 |
Enhancement of gamma-aminobutyric acid binding by quazepam, a benzodiazepine derivative with preferential affinity for type I benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cell Membrane; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Liquid chromatographic assay and pharmacokinetics of quazepam and its metabolites following sublingual administration of quazepam.
Topics: Administration, Sublingual; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Flurazepam; Humans; Male | 1988 |
Plasma quantification of quazepam and its 2-oxo and N-desmethyl metabolites by capillary gas chromatography.
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chromatography, Gas; Dealkylation; Half-Life; Humans; Kinetics | 1986 |
Several new benzodiazepines selectively interact with a benzodiazepine receptor subtype.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cerebellum; Flunitrazepam; Flurazepam; Hippocampus; Membranes; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Excretion of quazepam into human breast milk.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Female; Flurazepam; Humans; Milk, Human | 1984 |
Quazepam kinetics in the elderly.
Topics: Absorption; Administration, Oral; Aged; Aging; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chromatography, Gas; Female; Flurazepam; Half-Life; Humans; Kinetics; Male | 1984 |
Multiple-dose quazepam kinetics.
Topics: Absorption; Administration, Oral; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flurazepam; Humans; Kinetics; Male | 1984 |
Effect of sleep on quazepam kinetics.
Topics: Absorption; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flurazepam; Half-Life; Humans; Kinetics; Male; Random Allocation; Sleep; Time Factors | 1984 |
Analysis of quazepam and its metabolites in human urine by gas chromatography-mass spectrometry: application to a forensic case.
Topics: Benzodiazepines; Benzodiazepinones; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Male; Solid Phase Extraction; Substance Abuse Detection; Triazolam | 2013 |
Quantitative analysis of quazepam and its metabolites in human blood, urine, and bile by liquid chromatography-tandem mass spectrometry.
Topics: Benzodiazepines; Benzodiazepinones; Bile; Chromatography, Liquid; Flurazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Male; Middle Aged; Molecular Structure; Tandem Mass Spectrometry | 2014 |