Compounds > sc 58125
Page last updated: 2024-09-03

sc 58125 and sulindac

sc 58125 has been researched along with sulindac in 3 studies

Compound Research Comparison

Studies
(sc 58125)		Trials
(sc 58125)		Recent Studies (post-2010)
(sc 58125)		Studies
(sulindac)		Trials
(sulindac)		Recent Studies (post-2010) (sulindac)
930151,462202305

Protein Interaction Comparison

ProteinTaxonomysc 58125 (IC50)sulindac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)2.69
Aldo-keto reductase family 1 member B1Homo sapiens (human)2.69
Aldo-keto reductase family 1 member B1Bos taurus (cattle)0.293
Prostaglandin G/H synthase 2Homo sapiens (human)8.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chinery, R; Coffey, RJ; Damstrup, L; Daniel, VC; Dempsey, PJ; DuBois, RN; Graves-Deal, R; Hawkey, CJ; Jetton, TL; Kirkland, SC; Morrow, JD1
DuBois, RN; Zhang, Z1
Bottone, FG; Eling, TE; Ishibashi, M; Kamitani, H; Taniura, S; Watanabe, T1

Other Studies

3 other study(ies) available for sc 58125 and sulindac

ArticleYear
Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Jan-21, Volume: 94, Issue:2

    Topics: Amphiregulin; Cell Compartmentation; Cell Nucleus; Cell Polarity; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; EGF Family of Proteins; ErbB Receptors; Glycoproteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Mitosis; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; RNA, Neoplasm; Sulfonamides; Sulindac; Transforming Growth Factor alpha; Tumor Cells, Cultured

1997
Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells.
    Gastroenterology, 2000, Volume: 118, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Northern; Blotting, Western; Carrier Proteins; Colonic Neoplasms; Cyclooxygenase Inhibitors; DNA Fragmentation; Gene Expression; Humans; Intestinal Mucosa; Intracellular Signaling Peptides and Proteins; Nitrobenzenes; Protein Kinase C; Pyrazoles; RNA, Messenger; Sulfonamides; Sulindac; Tumor Cells, Cultured

2000
The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
    Experimental cell research, 2005, Jan-15, Volume: 302, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Line, Tumor; Cyclooxygenase Inhibitors; Densitometry; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Indomethacin; Kinetics; Laminin; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulindac

2005