sc 58125 has been researched along with nimesulide in 5 studies
| Studies (sc 58125) | Trials (sc 58125) | Recent Studies (post-2010) (sc 58125) | Studies (nimesulide) | Trials (nimesulide) | Recent Studies (post-2010) (nimesulide) |
|---|---|---|---|---|---|
| 93 | 0 | 15 | 1,272 | 200 | 271 |
| Protein | Taxonomy | sc 58125 (IC50) | nimesulide (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 2.1 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 6.2 | |
| Procathepsin L | Homo sapiens (human) | 1.92 | |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | 0.023 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.493 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 1.8947 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Churchill, L; Coutts, SJ; Cywin, CL; David, E; Engel, W; Graham, AG; Grob, PM; Hoermann, M; Kelly, TA; Lazer, ES; McNeil, DW; Meier, H; Meng, Z; Miao, CK; Potocki, I; Snow, RJ; Sorcek, R; Trummlitz, G; Tschantz, MA; Wong, HC | 1 |
| Meanwell, NA | 1 |
| Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Taketani, Y; Yamamoto, K; Yamamoto, S | 1 |
| DuBois, RN; Zhang, Z | 1 |
| Brunette, E; Gendron, TF; Mealing, GA; Morley, P; Nguyen, A; Tauskela, JS | 1 |
5 other study(ies) available for sc 58125 and nimesulide
| Article | Year |
|---|---|
Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Meloxicam; Membrane Proteins; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thiazines; Thiazoles | 1997 |
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Carrageenan; Cell Count; Cells, Cultured; Coloring Agents; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Excipients; Inflammation; Isoenzymes; Leukocytes; Male; Nitrobenzenes; Pleura; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2; Trypan Blue | 1996 |
Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Northern; Blotting, Western; Carrier Proteins; Colonic Neoplasms; Cyclooxygenase Inhibitors; DNA Fragmentation; Gene Expression; Humans; Intestinal Mucosa; Intracellular Signaling Peptides and Proteins; Nitrobenzenes; Protein Kinase C; Pyrazoles; RNA, Messenger; Sulfonamides; Sulindac; Tumor Cells, Cultured | 2000 |
Opposing effects of cyclooxygenase-2 selective inhibitors on oxygen-glucose deprivation-induced neurotoxicity.
Topics: Animals; Calcium; Canada; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Extracellular Space; Glucose Metabolism Disorders; Glutamates; Hypoxia; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Time Factors | 2004 |