sc 58125 has been researched along with indomethacin in 21 studies
| Studies (sc 58125) | Trials (sc 58125) | Recent Studies (post-2010) (sc 58125) | Studies (indomethacin) | Trials (indomethacin) | Recent Studies (post-2010) (indomethacin) |
|---|---|---|---|---|---|
| 93 | 0 | 15 | 29,527 | 1,838 | 3,396 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (57.14) | 18.2507 |
| 2000's | 9 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, GD; Burton, EG; Cogburn, JN; Collins, JT; Garland, DJ; Gregory, SA; Huang, HC; Isakson, PC; Koboldt, CM; Li, JJ | 1 |
| Anderson, GD; Collins, JT; Gregory, SA; Koboldt, CM; Li, JJ; Norton, MB; Perkins, WE; Reinhard, EJ; Reitz, DB; Seibert, K | 1 |
| Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY | 1 |
| Bornemeier, DA; Chan, K; Connor, DT; Doubleday, R; Dyer, RD; Gilbertsen, RB; Guglietta, A; Roth, BD; Schrier, DJ; Sercel, AD; Song, Y; Sorenson, RJ; Unangst, PC | 1 |
| Beylin, VG; Bornemeier, DA; Chan, K; Connor, DT; Doubleday, R; Dyer, RD; Gilbertsen, RB; Guglietta, A; Roth, BD; Schrier, DJ; Sercel, AD; Song, Y; Sorenson, RJ; Unangst, PC | 1 |
| Anderson, G; Bremer, M; Gierse, J; Gregory, S; Hauser, S; Koboldt, C; Leahy, K; Masferrer, J; Seibert, K; Zhang, Y | 1 |
| Hauser, S; Isakson, P; Leahy, K; Lee, L; Masferrer, J; Perkins, W; Seibert, K; Zhang, Y | 1 |
| Anderson, GD; Bremer, ME; Gregory, SA; Hauser, SD; Isakson, PC; McGarity, KL | 1 |
| Gardiner, NJ; Giblett, S; Grubb, BD; Willingale, HL | 1 |
| Erickson, BA; Kaminski, DL; Longo, WE; Mazuski, JE; Panesar, N | 1 |
| Chapman, K; McKnight, W; Wallace, JL | 1 |
| Hu, D; Syriatowicz, JP; Tracey, DJ; Walker, JS | 1 |
| Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
| Bagnato, A; Di Castro, V; Natali, PG; Nicotra, MR; Rosanò, L; Spinella, F | 1 |
| Goldsby, JS; Huang, JC; Matijevic-Aleksic, N; Wu, KK; Wun, WS | 1 |
| Bottone, FG; Eling, TE; Ishibashi, M; Kamitani, H; Taniura, S; Watanabe, T | 1 |
| Bernstein, SH; Chiorazzi, N; Felgar, RE; Kaur, K; Phipps, RP; Pollock, SJ; Ryan, EP | 1 |
| Hu, Q; Qiu, XW; Wang, ZR; Xu, ZQ; Zhang, J | 1 |
| Bernard, MP; Phipps, RP | 1 |
| Kato, H; Kojima, F; Matsushita, M; Naraba, H; Narumiya, S; Oh-Ishi, S; Sugimoto, Y; Ueno, A; Ushikubi, F; Yuhki, K | 1 |
| Hara, A; Hirose, Y; Hoshino, T; Murashita, H; Tabuchi, K; Tobita, T; Uemaetomari, I | 1 |
21 other study(ies) available for sc 58125 and indomethacin
| Article | Year |
|---|---|
1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Cyclopentanes; Dose-Response Relationship, Drug; Edema; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Sulfonamides; Sulfones | 1995 |
Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Cyclooxygenase Inhibitors; Cyclopentanes; Mice; Rats | 1994 |
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1997 |
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Humans; Hyperalgesia; Isoenzymes; Male; Membrane Proteins; Mice; Oxazoles; Phenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Thiazoles | 1999 |
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Humans; Hyperalgesia; In Vitro Techniques; Isoenzymes; Male; Membrane Proteins; Mice; Phenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sheep; Stomach Ulcer; Structure-Activity Relationship; Thiadiazoles | 1999 |
Expression and selective inhibition of constitutive and inducible forms of cyclooxygenase.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Gene Expression; Indomethacin; Inflammation; Isoenzymes; Organ Specificity; Prostaglandin-Endoperoxide Synthases; Pyrazoles; RNA, Messenger; Rodentia | 1995 |
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.
Topics: Abscess; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Gene Expression; Indomethacin; Inflammation; Male; Organ Specificity; Pain; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Stomach Diseases | 1994 |
Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Base Sequence; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; DNA Primers; Gene Expression; Gene Expression Regulation, Enzymologic; Indomethacin; Inflammation; Interleukin-6; Isoenzymes; Joints; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 1996 |
Functional consequences of the identification and localisation of cyclooxygenase isoforms in dorsal horn of rat spinal cord.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Electric Stimulation; Immunohistochemistry; Indomethacin; Isoenzymes; Nerve Fibers; Nociceptors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Reflex; Spinal Cord | 1997 |
The effect of selective cyclooxygenase inhibitors on intestinal epithelial cell mitogenesis.
Topics: Animals; Apoptosis; Blood; Blotting, Western; Cell Division; Cell Line; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA; Epithelial Cells; Indomethacin; Intestines; Isoenzymes; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Salicylates; Tumor Cells, Cultured | 1999 |
Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Interactions; Indomethacin; Inflammation; Isoenzymes; Leukocytes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Thiophenes | 1999 |
Hyperalgesia due to nerve injury: role of prostaglandins.
Topics: Animals; Cyclooxygenase Inhibitors; Functional Laterality; Hindlimb; Hyperalgesia; Indomethacin; Male; Meloxicam; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Sciatic Nerve; Thiazines; Thiazoles; Time Factors | 1999 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells.
Topics: Animals; Atrasentan; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Isoenzymes; Luciferases; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Nude; Nitrobenzenes; Ovarian Neoplasms; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrrolidines; Receptor, Endothelin A; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2004 |
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Topics: Animals; Arachidonic Acid; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Embryo Culture Techniques; Embryo, Mammalian; Epoprostenol; Female; Iloprost; Indomethacin; Intramolecular Oxidoreductases; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins F, Synthetic; Pyrazoles | 2004 |
The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Line, Tumor; Cyclooxygenase Inhibitors; Densitometry; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Indomethacin; Kinetics; Laminin; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulindac | 2005 |
Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells.
Topics: B-Lymphocytes; Cell Growth Processes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Enzyme Activation; Humans; Immunoglobulin Heavy Chains; Immunohistochemistry; Indomethacin; Isoxazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Nitrobenzenes; Pyrazoles; Sulfonamides; Sulfones; Thromboxane A2 | 2006 |
[Effects of selective cyclooxygenase-2 inhibitor on proliferation and apoptosis of human bladder cancer cell line T24].
Topics: Apoptosis; bcl-2-Associated X Protein; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Flow Cytometry; Humans; Indomethacin; Inhibitory Concentration 50; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Urinary Bladder Neoplasms | 2007 |
CpG oligodeoxynucleotides induce cyclooxygenase-2 in human B lymphocytes: implications for adjuvant activity and antibody production.
Topics: Adjuvants, Immunologic; B-Lymphocytes; Blotting, Western; Chloroquine; CpG Islands; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Induction; Flow Cytometry; Humans; Immunoglobulin G; Immunoglobulin M; Immunophenotyping; Indomethacin; Lymphocyte Activation; Oligonucleotides; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Complement C3; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Elapid Venoms; Epoprostenol; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Zymosan | 2008 |
The non-steroidal anti-inflammatory drugs protect mouse cochlea against acoustic injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Auditory Threshold; Cochlea; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Indomethacin; Isoxazoles; Lipoxygenase Inhibitors; Masoprocol; Meloxicam; Mice; Mice, Inbred Strains; Neuroprotective Agents; Pyrazoles; Sulfones; Thiazines; Thiazoles | 2008 |