Page last updated: 2024-09-03

sc 58125 and flurbiprofen

sc 58125 has been researched along with flurbiprofen in 3 studies

Compound Research Comparison

Studies
(sc 58125)
Trials
(sc 58125)
Recent Studies (post-2010)
(sc 58125)
Studies
(flurbiprofen)
Trials
(flurbiprofen)
Recent Studies (post-2010) (flurbiprofen)
930152,072466575

Protein Interaction Comparison

ProteinTaxonomysc 58125 (IC50)flurbiprofen (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)0.1683
Prostaglandin G/H synthase 1Homo sapiens (human)0.6754
Prostaglandin G/H synthase 2Homo sapiens (human)0.574
Aldo-keto reductase family 1 member C3Homo sapiens (human)1.56
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.5
Solute carrier family 22 member 6Homo sapiens (human)1.5
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.17

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bjarnason, I; Mahmud, T; Rafi, SS; Scott, DL; Wrigglesworth, JM1
Llorens, O; Mauleon, D; Palomer, A; Perez, JJ1
Lozano, JJ; Pouplana, R; Ruiz, J1

Other Studies

3 other study(ies) available for sc 58125 and flurbiprofen

ArticleYear
Nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation.
    Arthritis and rheumatism, 1996, Volume: 39, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Flurbiprofen; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pyrazoles; Rats; Rats, Sprague-Dawley; Thiophenes

1996
Structural basis of the dynamic mechanism of ligand binding to cyclooxygenase.
    Bioorganic & medicinal chemistry letters, 1999, Oct-04, Volume: 9, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flurbiprofen; Hydrogen Bonding; Isoenzymes; Ligands; Models, Molecular; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrazoles; Sheep

1999
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
    Journal of molecular graphics & modelling, 2002, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides

2002