sc 58125 has been researched along with dup 697 in 7 studies
| Studies (sc 58125) | Trials (sc 58125) | Recent Studies (post-2010) (sc 58125) | Studies (dup 697) | Trials (dup 697) | Recent Studies (post-2010) (dup 697) |
|---|---|---|---|---|---|
| 93 | 0 | 15 | 69 | 0 | 23 |
| Protein | Taxonomy | sc 58125 (IC50) | dup 697 (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 1.5705 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.6193 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0722 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, GD; Burton, EG; Cogburn, JN; Collins, JT; Garland, DJ; Gregory, SA; Huang, HC; Isakson, PC; Koboldt, CM; Li, JJ | 1 |
| Anderson, GD; Collins, JT; Gregory, SA; Koboldt, CM; Li, JJ; Norton, MB; Perkins, WE; Reinhard, EJ; Reitz, DB; Seibert, K | 1 |
| Baurin, N; Chavatte, P; Lesieur, D; Marot, C; Yous, S | 1 |
| Beswick, PJ; Blackaby, AP; Bountra, C; Brown, T; Browning, K; Campbell, IB; Corfield, J; Gleave, RJ; Guntrip, SB; Hall, RM; Hindley, S; Lambeth, PF; Lucas, F; Mathews, N; Naylor, A; Player, H; Price, HS; Sidebottom, PJ; Taylor, NL; Webb, G; Wiseman, J | 1 |
| Bjarnason, I; Mahmud, T; Rafi, SS; Scott, DL; Wrigglesworth, JM | 1 |
| Folco, GC | 1 |
| Chapman, K; McKnight, W; Wallace, JL | 1 |
1 review(s) available for sc 58125 and dup 697
| Article | Year |
|---|---|
New NSAIDs and gastroduodenal damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Membrane Proteins; Nitrobenzenes; Peptic Ulcer; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiophenes | 1996 |
6 other study(ies) available for sc 58125 and dup 697
| Article | Year |
|---|---|
1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Cyclopentanes; Dose-Response Relationship, Drug; Edema; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Sulfonamides; Sulfones | 1995 |
Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Cyclooxygenase Inhibitors; Cyclopentanes; Mice; Rats | 1994 |
Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis.
Topics: Benzene Derivatives; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cyclopentanes; Imidazoles; Isoenzymes; Isoxazoles; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrroles; Quantitative Structure-Activity Relationship; Spiro Compounds; Thiophenes | 2001 |
Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Topics: Biotransformation; Chemistry, Pharmaceutical; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Structure-Activity Relationship | 2009 |
Nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Flurbiprofen; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pyrazoles; Rats; Rats, Sprague-Dawley; Thiophenes | 1996 |
Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Interactions; Indomethacin; Inflammation; Isoenzymes; Leukocytes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Thiophenes | 1999 |