sc 58125 has been researched along with dinoprostone in 26 studies
| Studies (sc 58125) | Trials (sc 58125) | Recent Studies (post-2010) (sc 58125) | Studies (dinoprostone) | Trials (dinoprostone) | Recent Studies (post-2010) (dinoprostone) |
|---|---|---|---|---|---|
| 93 | 0 | 15 | 29,105 | 1,346 | 6,357 |
| Protein | Taxonomy | sc 58125 (IC50) | dinoprostone (IC50) |
|---|---|---|---|
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | 0.0155 | |
| Prostaglandin E2 receptor EP4 subtype | Homo sapiens (human) | 0.0031 | |
| Prostaglandin E2 receptor EP4 subtype | Rattus norvegicus (Norway rat) | 0.0021 | |
| Prostaglandin E2 receptor EP3 subtype | Homo sapiens (human) | 0.002 | |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | 0.0087 | |
| Prostacyclin receptor | Homo sapiens (human) | 0.26 | |
| Prostaglandin E2 receptor EP2 subtype | Rattus norvegicus (Norway rat) | 0.0052 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 15 (57.69) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, GD; Bremer, ME; Gregory, SA; Hauser, SD; Isakson, PC; McGarity, KL | 1 |
| Cao, HJ; Evans, CH; Frobert, Y; Rezanka, LJ; Sciaky, D; Smith, TJ; Wang, HS; Winn, VD; Young, DA | 1 |
| Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Taketani, Y; Yamamoto, K; Yamamoto, S | 1 |
| Bonazzi, A; Boraschi, D; Cassina, E; Folco, G; Habib, A; Hernandez, A; Lebret, M; Maclouf, J; Sala, A; Viganò, T | 1 |
| Beauchamp, RD; DuBois, RN; Morrow, JD; Shao, J; Sheng, H | 1 |
| Fürstenberger, G; Kopp-Schneider, A; Marks, F; Müller-Decker, K; Seibert, K | 1 |
| Erickson, BA; Kaminski, DL; Longo, WE; Mazuski, JE; Panesar, N | 1 |
| Kaminski, DL; Longo, WE; Mazuski, J; Panesar, N | 1 |
| Gilbertsen, R; Guglietta, A; Kraus, ER; Lesch, CA; Sanchez, B | 1 |
| Kaminski, D; Longo, WE; Mazuski, JE; Panesar, N | 1 |
| Grossman, EM; Kaminski, DL; Longo, WE; Mazuski, JE; Panesar, N | 1 |
| Conway, CM; Dirig, DM; Isakson, PC; Luo, ZD; Svensson, C; Yaksh, TL | 1 |
| Han, R; Smith, TJ; Tsui, S | 1 |
| Bozza, PT; Pacheco, P; Weller, PF; Yu, W | 1 |
| Bagnato, A; Di Castro, V; Natali, PG; Nicotra, MR; Rosanò, L; Spinella, F | 1 |
| Fujino, T; Fukuzawa, J; Hara, A; Hasebe, N; Hosoki, Y; Kikuchi, K; Kuriyama, S; Nakagawa, N; Narumiya, S; Takahata, O; Takayama, K; Taniguchi, T; Ushikubi, F; Yamada, T; Yuhki, K | 1 |
| Goldsby, JS; Huang, JC; Matijevic-Aleksic, N; Wu, KK; Wun, WS | 1 |
| Brunette, E; Gendron, TF; Morley, P; Tauskela, JS | 1 |
| Chen, J; Graham, SH; Hickey, RW; Kawaguchi, K; Rose, ME; Zhu, L | 1 |
| Abe, M; Ding, J; Goto, R; Hiraki, E; Hoshikawa, H; Katsukawa, M; Mori, N; Tsuboi, K; Ueda, N; Yamamoto, S | 1 |
| Bernstein, SH; Chiorazzi, N; Felgar, RE; Kaur, K; Phipps, RP; Pollock, SJ; Ryan, EP | 1 |
| Kajiyama, S; Kawamoto, M; Kurita, S; Matsunaga, A; Shiraishi, S; Yasuda, T; Yuge, O | 1 |
| Adelson, PD; Chang, YF; Davis, DS; Graham, SH; Hickey, RW; Johnnides, MJ; Rose, ME; Yu, Z | 1 |
| Bernard, MP; Phipps, RP | 1 |
| Kato, H; Kojima, F; Matsushita, M; Naraba, H; Narumiya, S; Oh-Ishi, S; Sugimoto, Y; Ueno, A; Ushikubi, F; Yuhki, K | 1 |
| Abbate, A; Al-Husseini, A; Chalfant, CE; Drake, JI; Farkas, L; Kraskauskas, D; Van Tassel, B; Voelkel, NF; Wijesinghe, DS | 1 |
26 other study(ies) available for sc 58125 and dinoprostone
| Article | Year |
|---|---|
Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Base Sequence; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; DNA Primers; Gene Expression; Gene Expression Regulation, Enzymologic; Indomethacin; Inflammation; Interleukin-6; Isoenzymes; Joints; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 1996 |
Leukoregulin induction of prostaglandin-endoperoxide H synthase-2 in human orbital fibroblasts. An in vitro model for connective tissue inflammation.
Topics: Blotting, Northern; Blotting, Western; Cyclic AMP; Cycloheximide; Dexamethasone; Dinoprostone; Electrophoresis, Gel, Two-Dimensional; Enzyme Induction; Fibroblasts; Humans; Lymphokines; Microscopy, Phase-Contrast; Mifepristone; Orbit; Prostaglandin-Endoperoxide Synthases; Pyrazoles; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1996 |
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Carrageenan; Cell Count; Cells, Cultured; Coloring Agents; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Excipients; Inflammation; Isoenzymes; Leukocytes; Male; Nitrobenzenes; Pleura; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2; Trypan Blue | 1996 |
Cyclooxygenase-2 and synthesis of PGE2 in human bronchial smooth-muscle cells.
Topics: Arachidonic Acid; Blotting, Western; Bronchi; Cells, Cultured; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Humans; Immunoblotting; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoenzymes; Membrane Proteins; Muscle, Smooth; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptors, Interleukin-1; Sialoglycoproteins | 1997 |
Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells.
Topics: Animals; Apoptosis; Clone Cells; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Humans; Immunoblotting; Isoenzymes; Membrane Proteins; Mice; Mice, Nude; Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Stem Cells; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Epidermis; Female; Immunohistochemistry; Isoenzymes; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
The effect of selective cyclooxygenase inhibitors on intestinal epithelial cell mitogenesis.
Topics: Animals; Apoptosis; Blood; Blotting, Western; Cell Division; Cell Line; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA; Epithelial Cells; Indomethacin; Intestines; Isoenzymes; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Salicylates; Tumor Cells, Cultured | 1999 |
Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents.
Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Epithelial Cells; Humans; Immunoblotting; Interleukin-1; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
Lack of beneficial effect of COX-2 inhibitors in an experimental model of colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Male; Nitrobenzenes; Peroxidase; Peroxidases; Phenols; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazoles; Trinitrobenzenesulfonic Acid | 1999 |
Synthetic pathways of gallbladder mucosal prostanoids: the role of cyclooxygenase-1 and 2.
Topics: 6-Ketoprostaglandin F1 alpha; Blotting, Western; Cholecystitis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gallbladder; Gallbladder Neoplasms; Humans; Isoenzymes; Lipopolysaccharides; Lysophosphatidylcholines; Male; Membrane Proteins; Middle Aged; Mucous Membrane; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Sulfonamides; Tumor Cells, Cultured | 1999 |
The role of cyclooxygenase enzymes in the growth of human gall bladder cancer cells.
Topics: Apoptosis; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Replication; DNA, Neoplasm; Gallbladder Neoplasms; Humans; Isoenzymes; Membrane Proteins; Mitogens; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substrate Specificity; Tumor Cells, Cultured | 2000 |
The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Ibuprofen; Injections, Intraperitoneal; Injections, Spinal; Isoenzymes; Male; Membrane Proteins; N-Methylaspartate; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2001 |
Up-regulation of prostaglandin E2 synthesis by interleukin-1beta in human orbital fibroblasts involves coordinate induction of prostaglandin-endoperoxide H synthase-2 and glutathione-dependent prostaglandin E2 synthase expression.
Topics: Blotting, Northern; Blotting, Western; CD40 Ligand; Cyclooxygenase Inhibitors; Cytoplasm; Dexamethasone; Dinoprostone; DNA, Complementary; Enzyme Inhibitors; Fibroblasts; Glucocorticoids; Glutathione; Humans; Interleukin-1; Intramolecular Oxidoreductases; Luciferases; Microsomes; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Structure, Tertiary; Pyrazoles; RNA; RNA, Messenger; Time Factors; Transfection; Up-Regulation | 2002 |
NS-398: cyclooxygenase-2 independent inhibition of leukocyte priming for lipid body formation and enhanced leukotriene generation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Leukocytes; Leukotriene B4; Leukotrienes; Lipid Metabolism; Mice; Mice, Knockout; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells.
Topics: Animals; Atrasentan; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Isoenzymes; Luciferases; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Nude; Nitrobenzenes; Ovarian Neoplasms; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrrolidines; Receptor, Endothelin A; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2004 |
Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP.
Topics: Animals; Blood Pressure; Creatinine; Crosses, Genetic; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Gene Expression Regulation; Genetic Predisposition to Disease; Hypertension, Renal; Infarction; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptors, Epoprostenol; Renal Circulation; Renin-Angiotensin System; RNA, Messenger | 2004 |
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Topics: Animals; Arachidonic Acid; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Embryo Culture Techniques; Embryo, Mammalian; Epoprostenol; Female; Iloprost; Indomethacin; Intramolecular Oxidoreductases; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins F, Synthetic; Pyrazoles | 2004 |
The dual role of prostaglandin E(2) in excitotoxicity and preconditioning-induced neuroprotection.
Topics: Animals; Brain; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Female; Fetus; Gene Expression; Glucose; Male; Neuroglia; Neurons; Pregnancy; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger | 2005 |
Cyclooxygenase-2 expression is induced in rat brain after kainate-induced seizures and promotes neuronal death in CA3 hippocampus.
Topics: Animals; Cell Death; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Hippocampus; Kainic Acid; Male; Neurons; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley | 2005 |
Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors.
Topics: Arachidonic Acid; Blotting, Western; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Humans; Multiple Myeloma; Phorbol Esters; Prostaglandin D2; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2006 |
Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells.
Topics: B-Lymphocytes; Cell Growth Processes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Enzyme Activation; Humans; Immunoglobulin Heavy Chains; Immunohistochemistry; Indomethacin; Isoxazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Nitrobenzenes; Pyrazoles; Sulfonamides; Sulfones; Thromboxane A2 | 2006 |
Intrathecally administered COX-2 but not COX-1 or COX-3 inhibitors attenuate streptozotocin-induced mechanical hyperalgesia in rats.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dinoprostone; Hyperalgesia; Injections, Spinal; Male; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Streptozocin | 2007 |
Cyclooxygenase-2 activity following traumatic brain injury in the developing rat.
Topics: Animals; Animals, Newborn; Brain Injuries; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Male; Maze Learning; Neuroprotective Agents; Pyrazoles; Rats; Rats, Sprague-Dawley | 2007 |
CpG oligodeoxynucleotides induce cyclooxygenase-2 in human B lymphocytes: implications for adjuvant activity and antibody production.
Topics: Adjuvants, Immunologic; B-Lymphocytes; Blotting, Western; Chloroquine; CpG Islands; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Induction; Flow Cytometry; Humans; Immunoglobulin G; Immunoglobulin M; Immunophenotyping; Indomethacin; Lymphocyte Activation; Oligonucleotides; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Complement C3; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Elapid Venoms; Epoprostenol; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Zymosan | 2008 |
Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arterioles; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diethylcarbamazine; Dinoprost; Dinoprostone; Humans; Hypertension, Pulmonary; Hypoxia; Inflammation; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Male; Prostaglandins F; Pulmonary Artery; Pyrazoles; Rats; Rats, Sprague-Dawley; Thromboxane B2; Ventricular Function, Right | 2015 |