Page last updated: 2024-09-03

sc 58125 and dinoprost

sc 58125 has been researched along with dinoprost in 5 studies

Compound Research Comparison

Studies
(sc 58125)
Trials
(sc 58125)
Recent Studies (post-2010)
(sc 58125)
Studies
(dinoprost)
Trials
(dinoprost)
Recent Studies (post-2010) (dinoprost)
9301511,5549401,936

Protein Interaction Comparison

ProteinTaxonomysc 58125 (IC50)dinoprost (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.0025
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.0713
Prostaglandin G/H synthase 1Homo sapiens (human)0.14
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.3
Prostaglandin G/H synthase 2Homo sapiens (human)0.14
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)4.2
Prostaglandin F2-alpha receptorBos taurus (cattle)0.14
Prostaglandin F2-alpha receptorHomo sapiens (human)0.0139
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.216
Prostaglandin D2 receptorHomo sapiens (human)4.5
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.287

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaminski, DL; Longo, WE; Mazuski, J; Panesar, N1
Becker, BF; Heindl, B1
Abe, M; Ding, J; Goto, R; Hiraki, E; Hoshikawa, H; Katsukawa, M; Mori, N; Tsuboi, K; Ueda, N; Yamamoto, S1
Bernstein, SH; Chiorazzi, N; Felgar, RE; Kaur, K; Phipps, RP; Pollock, SJ; Ryan, EP1
Abbate, A; Al-Husseini, A; Chalfant, CE; Drake, JI; Farkas, L; Kraskauskas, D; Van Tassel, B; Voelkel, NF; Wijesinghe, DS1

Other Studies

5 other study(ies) available for sc 58125 and dinoprost

ArticleYear
Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents.
    Prostaglandins & other lipid mediators, 1998, Volume: 56, Issue:5-6

    Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Epithelial Cells; Humans; Immunoblotting; Interleukin-1; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate

1998
Aspirin, but not the more selective cyclooxygenase (COX)-2 inhibitors meloxicam and SC 58125, aggravates postischaemic cardiac dysfunction, independent of COX function.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:2

    Topics: Animals; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Eicosanoids; F2-Isoprostanes; Guinea Pigs; Heart; Hemodynamics; Isoenzymes; Male; Meloxicam; Myocardial Ischemia; Myocardial Reperfusion Injury; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Thiazines; Thiazoles; Thromboxane A2

2001
Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:4

    Topics: Arachidonic Acid; Blotting, Western; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Humans; Multiple Myeloma; Phorbol Esters; Prostaglandin D2; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2006
Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells.
    Clinical immunology (Orlando, Fla.), 2006, Volume: 120, Issue:1

    Topics: B-Lymphocytes; Cell Growth Processes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Enzyme Activation; Humans; Immunoglobulin Heavy Chains; Immunohistochemistry; Indomethacin; Isoxazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Nitrobenzenes; Pyrazoles; Sulfonamides; Sulfones; Thromboxane A2

2006
Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arterioles; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diethylcarbamazine; Dinoprost; Dinoprostone; Humans; Hypertension, Pulmonary; Hypoxia; Inflammation; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Male; Prostaglandins F; Pulmonary Artery; Pyrazoles; Rats; Rats, Sprague-Dawley; Thromboxane B2; Ventricular Function, Right

2015