Page last updated: 2024-09-03

sc 53116 and tropisetron

sc 53116 has been researched along with tropisetron in 3 studies

Compound Research Comparison

Studies
(sc 53116)
Trials
(sc 53116)
Recent Studies (post-2010)
(sc 53116)
Studies
(tropisetron)
Trials
(tropisetron)
Recent Studies (post-2010) (tropisetron)
2003944218150

Protein Interaction Comparison

ProteinTaxonomysc 53116 (IC50)tropisetron (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.1623
Muscarinic acetylcholine receptor M2Homo sapiens (human)3.1623
Muscarinic acetylcholine receptor M5Homo sapiens (human)3.45
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)1.8
Sodium-dependent serotonin transporterHomo sapiens (human)0.488
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)1.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bockaert, J; Claeysen, S; Dumuis, A; Journot, L; Sebben, M1
Fischmeister, R; Langlois, M1
Flynn, DL; Goldstin, B; Gullikson, GW; Moormann, AE; Yang, DC1

Reviews

1 review(s) available for sc 53116 and tropisetron

ArticleYear
5-HT4 receptor ligands: applications and new prospects.
    Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3

    Topics: Animals; Benzamides; Benzimidazoles; Benzoates; Binding Sites; Cardiovascular Physiological Phenomena; Central Nervous System; Digestive System Physiological Phenomena; Humans; Indoles; Ketones; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

2 other study(ies) available for sc 53116 and tropisetron

ArticleYear
Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.
    FEBS letters, 1996, Nov-25, Volume: 398, Issue:1

    Topics: Age Factors; Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Binding Sites; Brain; Brain Chemistry; Cloning, Molecular; Inferior Colliculi; Mice; Molecular Sequence Data; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Transfection

1996
SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:3

    Topics: 4-Aminobenzoic Acid; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Esophagus; Imidazoles; In Vitro Techniques; Indoles; Male; Mucous Membrane; Muscle Contraction; Muscle, Smooth; para-Aminobenzoates; Pyrroles; Rats; Receptors, Cell Surface; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron; Tryptamines

1993