sc 53116 has been researched along with metoclopramide in 3 studies
| Studies (sc 53116) | Trials (sc 53116) | Recent Studies (post-2010) (sc 53116) | Studies (metoclopramide) | Trials (metoclopramide) | Recent Studies (post-2010) (metoclopramide) |
|---|---|---|---|---|---|
| 20 | 0 | 3 | 5,044 | 1,216 | 623 |
| Protein | Taxonomy | sc 53116 (IC50) | metoclopramide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 2.383 | |
| Myeloperoxidase | Homo sapiens (human) | 0.35 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.721 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.8 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.127 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 7.8 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.675 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 2.383 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 7.8 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.2 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.88 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.63 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.6237 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, DP; Flynn, DL; Gullikson, GW; Moummi, C; Nosal, R; Villamil, CI; Yang, DC; Zabrowski, DL | 1 |
| Bockaert, J; Claeysen, S; Dumuis, A; Journot, L; Sebben, M | 1 |
| Fujiwara, I; Harada, H; Hirokawa, Y; Kato, S; Suzuki, K; Yoshida, N; Yoshikawa, T | 1 |
3 other study(ies) available for sc 53116 and metoclopramide
| Article | Year |
|---|---|
SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype.
Topics: Animals; Benzamides; Heterocyclic Compounds; Pyrroles; Rats; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship | 1992 |
Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.
Topics: Age Factors; Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Binding Sites; Brain; Brain Chemistry; Cloning, Molecular; Inferior Colliculi; Mice; Molecular Sequence Data; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Transfection | 1996 |
Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
Topics: Animals; Antiemetics; Azepines; Brain; Crystallography, X-Ray; Dogs; Dopamine Antagonists; Ferrets; In Vitro Techniques; Models, Molecular; Pyridines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship | 2003 |