sc 53116 has been researched along with cisapride in 6 studies
| Studies (sc 53116) | Trials (sc 53116) | Recent Studies (post-2010) (sc 53116) | Studies (cisapride) | Trials (cisapride) | Recent Studies (post-2010) (cisapride) |
|---|---|---|---|---|---|
| 20 | 0 | 3 | 1,554 | 390 | 110 |
| Protein | Taxonomy | sc 53116 (IC50) | cisapride (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.767 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 3.37 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.3 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0098 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 3.5923 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.07 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.1701 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.35 | |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | 2.69 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0098 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 3.37 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 2.29 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 3.3827 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.26 | |
| D | Rattus norvegicus (Norway rat) | 0.0065 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 3.6495 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0065 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 1.7 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0065 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0065 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 2.29 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.0065 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.083 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0054 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.2597 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 3.6495 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 4.47 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 4.47 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0098 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.384 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.03 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 3.37 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.03 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.144 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.9 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0407 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 2.29 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.535 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.2536 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 0.1701 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.994 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, DP; Flynn, DL; Gullikson, GW; Moummi, C; Nosal, R; Villamil, CI; Yang, DC; Zabrowski, DL | 1 |
| Bockaert, J; Claeysen, S; Dumuis, A; Journot, L; Sebben, M | 1 |
| Fischmeister, R; Langlois, M | 1 |
| Fujiwara, I; Harada, H; Hirokawa, Y; Kato, S; Suzuki, K; Yoshida, N; Yoshikawa, T | 1 |
| Becker, DP; Flynn, DL; Gullikson, GW; Loeffler, R; Moormann, AE; Moummi, C; Nosal, R; Villamil, CI; Yang, DC | 1 |
| Kamato, T; Miyata, K; Nagakura, Y; Yamano, M | 1 |
1 review(s) available for sc 53116 and cisapride
| Article | Year |
|---|---|
5-HT4 receptor ligands: applications and new prospects.
Topics: Animals; Benzamides; Benzimidazoles; Benzoates; Binding Sites; Cardiovascular Physiological Phenomena; Central Nervous System; Digestive System Physiological Phenomena; Humans; Indoles; Ketones; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
5 other study(ies) available for sc 53116 and cisapride
| Article | Year |
|---|---|
SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype.
Topics: Animals; Benzamides; Heterocyclic Compounds; Pyrroles; Rats; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship | 1992 |
Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.
Topics: Age Factors; Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Binding Sites; Brain; Brain Chemistry; Cloning, Molecular; Inferior Colliculi; Mice; Molecular Sequence Data; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Transfection | 1996 |
Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
Topics: Animals; Antiemetics; Azepines; Brain; Crystallography, X-Ray; Dogs; Dopamine Antagonists; Ferrets; In Vitro Techniques; Models, Molecular; Pyridines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship | 2003 |
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
Topics: Amides; Animals; Benzamides; Bradycardia; Brain; Dogs; Esophagus; Esters; Female; Gastric Emptying; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Pyrroles; Pyrrolizidine Alkaloids; Radioligand Assay; Rats; Rats, Wistar; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Structure-Activity Relationship | 2006 |
Effects of gastroprokinetic agents on gastroparesis in streptozotocin-induced diabetic rats.
Topics: Animals; Benzamides; Benzimidazoles; Blood Glucose; Cisapride; Diabetes Mellitus, Experimental; Gastric Emptying; Gastrointestinal Motility; Gastroparesis; Granisetron; Male; Morpholines; Ondansetron; Piperidines; Pyrroles; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Vagotomy | 1997 |